Lab | Description | Staff | Location | Research Areas |
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Dr. Adams comes from a rich background including industry, government, academic, and nonprofit settings. Throughout, he has focused on applying leading edge genomic and bioinformatic approaches to a variety of research problems in biology. |
Farmington, CT | ||
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Investigates how RNA splicing contributes to breast and ovarian cancer progression, metastasis and drug-resistance. |
Farmington, CT | Genetics and Genomics|Cancer | |
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Functional genomics and epigenetic modification |
Bar Harbor, ME | ||
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Enabling the development of novel therapies for serious illnesses. |
Farmington, CT | Computational Biology|Genetics and Genomics|Bioinformatics|Aging|Immune Disorders|Cancer|Infectious Disease Research | |
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The Beck lab uses genomics, bioinformatics and molecular biological techniques to investigate the ways in which repetitive DNA elements, such as transposons, affect human genomes. |
Farmington, CT | ||
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Researches genome informatics with a focus on gene ontology. |
Bar Harbor, ME | Genetics and Genomics|Computational Biology|Bioinformatics|Resource Development and Dissemination|Diabetes and Obesity|Cancer|Developmental Disorders|Infectious Disease Research|Neurodegenerative and Neuromuscular Diseases | |
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Bar Harbor, ME | ||
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Researching meiosis, the mechanisms of DNA damage detection and repair during normal development of gametes, and implications for fertility of cancer patients after radiation and chemotherapy. |
Bar Harbor, ME | Cancer|Genetics and Genomics|Reproductive Disorders | |
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Investigating gamete development with a focus on spermatogenesis. |
Bar Harbor, ME | Developmental Disorders|Reproductive Disorders | |
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Bridging the digital biology divide, integrating computation with biomedical research. |
Bar Harbor, ME | Computational Biology|Genetics and Genomics|Resource Development and Dissemination|Cancer|Developmental Disorders | |
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Studies synapse development and function relevant to human neuromuscular disorders. |
Bar Harbor, ME | Genetics and Genomics|Neurodegenerative and Neuromuscular Diseases|Developmental Disorders | |
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Developing new computational strategies to understand complex genetic systems. |
Bar Harbor, ME | Genetics and Genomics|Computational Biology|Bioinformatics|Diabetes and Obesity|Immune Disorders|Cancer|Reproductive Disorders|Complex Traits | |
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The Cheng lab develops technologies based on artificial DNA and RNA binding proteins and applies them to sense or induce sequence or epigenetic changes at target genomic loci or target transcripts. |
Farmington, CT | Aging|Bioinformatics|Genetics and Genomics|Computational Biology|Cancer | |
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Researches the genetics underlying behavior and identifies relationships among behavioral traits. |
Bar Harbor, ME | Aging|Behavioral Disorders|Bioinformatics|Complex Traits|Computational Biology|Genetics and Genomics|Resource Development and Dissemination | |
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Analyzing sequence and assay data to better understand genome function. |
Farmington, CT | Genetics and Genomics|Bioinformatics|Computational Biology|Cancer|Complex Traits|Developmental Disorders|Neurodegenerative and Neuromuscular Diseases|Diabetes and Obesity | |
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Investigating the genetics of health and disease with a systems approach. |
Bar Harbor, ME | Computational Biology|Complex Traits|Genetics and Genomics|Bioinformatics|Aging|Diabetes and Obesity | |
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Researches the molecular pathways of human degenerative muscle diseases. |
Bar Harbor, ME | Genetics and Genomics|Complex Traits|Neurodegenerative and Neuromuscular Diseases|Aging | |
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Researching the mechanisms that generate genetic diversity through the lens of evolution |
Bar Harbor, ME | Complex Traits|Computational Biology|Genetics and Genomics|Reproductive Disorders | |
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Investigates the genetic regulation of meiosis and the mechanisms of male fertility to understand how errors in meiosis can lead to developmental abnormalities. |
Bar Harbor, ME | Reproductive Disorders|Developmental Disorders|Genetics and Genomics | |
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Researches the genetics of aging and lifespan, seeking to understand the basic mechanisms of aging, and adult stem cells, with the goal of delaying normal aging processes. |
Bar Harbor, ME | ||
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Utilizing genomic approaches to interrogate mechanisms of inherited cardiovascular disorders. |
Farmington, CT | Genetics and Genomics | |
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Investigates the early stages of age-related neurodegenerative diseases. |
Bar Harbor, ME | Genetics and Genomics|Neurodegenerative and Neuromuscular Diseases|Bioinformatics|Aging | |
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I lead a collaborative and interinstitutional research program that uses a multidisciplinary approach to identify early causative events underlying ‘normal’ nonpathological age-related memory decline and Alzheimer’s dementia. |
Bar Harbor, ME | ||
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Ke Lab studies RNA from birth to death during organism neurological development, and its malfunctions in diseases for effective therapies in clinics. |
Bar Harbor, ME | Bioinformatics|Computational Biology|Behavioral Disorders|Complex Traits|Developmental Disorders|Neurodegenerative and Neuromuscular Diseases | |
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Studies the genetics of kidney function and disease, particularly in the context of aging. |
Bar Harbor, ME | Complex Traits|Genetics and Genomics|Aging|Diabetes and Obesity | |
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Studies neural circuits in the brain and associated behavioral abnormalities. |
Bar Harbor, ME | Genetics and Genomics|Neurodegenerative and Neuromuscular Diseases|Behavioral Disorders | |
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Using genomic technologies and mouse modeling including patient-derived xenografts (PDX) and genetically engineered mouse models (GEMM), we are discovering and validating novel biomarkers and therapeutic targets of pediatric cancers |
Farmington, CT | ||
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The Lee Lab's study of structural genomic variation in human biology, evolution and disease |
Farmington, CT | Computational Biology|Genetics and Genomics|Bioinformatics|Behavioral Disorders|Aging|Cancer|Neurodegenerative and Neuromuscular Diseases|Reproductive Disorders|Developmental Disorders | |
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Assessing the performance of next-generation sequencing techniques in accurate genome/epigenome/transcriptome profiling and understanding the clinical and functional role of epigenome heterogeneity in the cancer evolution. |
Open PositionsThe Li Lab has the current open positions. |
Farmington, CT | Computational Biology|Bioinformatics |
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Researching the fundamental genomics of breast cancer. |
Farmington, CT | Genetics and Genomics|Cancer | |
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Steven Munger, Ph.D., uses a systems genetics approach and advanced computational methods to study development and complex disease in advanced mouse populations. |
Bar Harbor, ME | Bioinformatics|Genetics and Genomics | |
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We investigate how signaling programs instruct in vivo stem cells of the cochlea to differentiate into a highly specialized, organized sensory epithelium. |
Bar Harbor, ME | ||
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Investigating the genetic mechanisms of craniofacial development and developing new genetic tools and resources for the scientific community. |
Bar Harbor, ME | Genetics and Genomics|Resource Development and Dissemination | |
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Investigates the genetics of metabolic syndrome and ciliopathies. |
Bar Harbor, ME | Computational Biology|Complex Traits|Bioinformatics|Diabetes and Obesity|Developmental Disorders|Genetics and Genomics|Neurodegenerative and Neuromuscular Diseases | |
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Employs mouse models of human eye disease to study gene function and mechanisms underlying disease pathology. |
Open Positions |
Bar Harbor, ME | Genetics and Genomics|Resource Development and Dissemination|Complex Traits|Behavioral Disorders|Aging|Diabetes and Obesity|Developmental Disorders|Neurodegenerative and Neuromuscular Diseases |
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Bar Harbor, ME | Diabetes and Obesity|Behavioral Disorders | |
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The Oh Lab studies the human microbiome for its potential to deliver treatments for infectious and other diseases. (Image by Alex Valm, NHGRI) |
Farmington, CT | Genetics and Genomics|Infectious Disease Research|Bioinformatics | |
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Studying the mechanisms of human immunity and developing cancer immunotherapies. |
Farmington, CT | Computational Biology|Genetics and Genomics|Complex Traits|Bioinformatics|Aging|Diabetes and Obesity|Immune Disorders|Infectious Disease Research|Cancer | |
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Human pluripotent stem cells and the human embryo: Human pluripotent stem cells (hPSC) have opened up a previously inaccessible phase of the human life cycle to experimental study. |
Open Positions |
Bar Harbor, ME | |
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Researches blood formation with a focus on red blood cells and the genetics underlying defects leading to anemias. |
Bar Harbor, ME | Genetics and Genomics|Complex Traits|Aging | |
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Dr. Reinholdt’s research focuses on comparative and functional mammalian genomics, reproductive development and stem cell biology. |
Bar Harbor, ME | Genetics and Genomics|Complex Traits|Resource Development and Dissemination|Bioinformatics|Reproductive Disorders|Developmental Disorders | |
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To study tumor microenvironment and tumor immunology in cancer therapeutic resistance and metastatic relapse |
Bar Harbor, ME | Cancer|Aging|Immune Disorders | |
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Captures gene expression data and disseminates it to the research community. |
Bar Harbor, ME | Bioinformatics|Developmental Disorders|Genetics and Genomics|Resource Development and Dissemination | |
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Develops algorithms and software for the analysis of exome and genome sequences. |
Farmington, CT | Skin Disease|Computational Biology|Genetics and Genomics | |
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Investigating the mechanisms of autoimmune disease to devise therapeutic approaches. |
Bar Harbor, ME | Computational Biology|Complex Traits|Resource Development and Dissemination|Immune Disorders|Cancer|Infectious Disease Research | |
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Global leader in the use of targeted mutagenesis in mice to investigate muscle development, disease and repair. |
Bar Harbor, ME | Developmental Disorders|Genetics and Genomics|Aging|Neurodegenerative and Neuromuscular Diseases | |
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Elucidating the structures and dynamics of complex genomes. |
Farmington, CT | Genetics and Genomics | |
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The overall focus of my research program has been to understand the molecular and cellular mechanisms underlying tissue growth and tissue regeneration with the long-term goal of developing new strategies for treating human diseases. |
Farmington, CT | ||
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Investigating the genetic basis of autoimmunity and type 1 diabetes. |
Bar Harbor, ME | Genetics and Genomics|Immune Disorders|Complex Traits|Diabetes and Obesity | |
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Investigates human immunological diseases and malignancy through the development and leveraging of novel humanized mouse models |
Bar Harbor, ME | Genetics and Genomics|Resource Development and Dissemination|Diabetes and Obesity|Cancer|Immune Disorders|Infectious Disease Research | |
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The application of high-resolution mass spectrometry now enables the measurement in human samples the metabolome, lipidome and small molecules of dietary, microbial and environmental origins |
Farmington, CT | Bioinformatics|Computational Biology|Immune Disorders | |
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Researches human pancreatic islet cells and the genetic and environmental bases of type 2 diabetes. |
Farmington, CT | Genetics and Genomics|Bioinformatics|Diabetes and Obesity|Developmental Disorders|Aging | |
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Pathology is the mother of medicine. |
Bar Harbor, ME | Genetics and Genomics|Aging | |
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Investigates the molecular mechanisms shaping hair cell architecture in the inner ear |
Bar Harbor, ME | Genetics and Genomics|Developmental Disorders | |
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Our lab is focused on identifying and understanding the precise genetic mechanisms influencing human complex traits and risk to disease. To accomplish this our work spans several areas of interest. |
Bar Harbor, ME | Bioinformatics|Complex Traits|Computational Biology|Genetics and Genomics|Immune Disorders | |
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Researches regulation of stem cells in the blood in normal development, aging and leukemia transformation. |
Bar Harbor, ME | Genetics and Genomics|Immune Disorders|Cancer|Aging | |
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Develops computational methods to study the epigenetic regulation of gene expression and its implications in important human conditions including aging and common diseases. |
Farmington, CT | Genetics and Genomics|Computational Biology|Bioinformatics|Aging|Immune Disorders | |
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The Unutmaz Lab investigates the biology of the human immune system. |
Farmington, CT | ||
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Brain tumors, sequencing, computational biology. |
Farmington, CT | Bioinformatics|Cancer | |
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Leverages advanced technologies to investigate infectious diseases, human and other mammalian microbiomes, and their clinical impact. |
Farmington, CT | Computational Biology|Complex Traits|Genetics and Genomics|Bioinformatics | |
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Bridges immunology, genomics research and bioinformatics to develop a deeper understanding of asthma pathogenesis. |
Farmington, CT | Genetics and Genomics|Immune Disorders |
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