Research Labs

Lab	Description	Location	Research Areas
The Tarchini Lab Principal Investigator Basile Tarchini, Ph.D. Bar Harbor, ME	Investigates the molecular mechanisms shaping hair cell architecture in the inner ear Genetics and Genomics Developmental Disorders	Bar Harbor, ME	Genetics and Genomics\|Developmental Disorders
The Adams Lab Principal Investigator Mark Adams, Ph.D. Farmington, CT	The Adams lab develops new approaches for human and mouse microbiome analysis, seeks to understand the evolution of antibiotic resistance in Gram-negative pathogens, and contributes to clinical assay development for the JAX CLIA Laboratory. Infectious Disease Research Genetics and Genomics	Farmington, CT	Infectious Disease Research\|Genetics and Genomics
The Agoro Lab Principal Investigator Rafiou Agoro, Ph.D. Bar Harbor, ME	The Agoro lab uses systems biology approaches to determine how iron-driven kidney oxidative stress influences FGF23-mediated phosphate excretion in aging, chronic kidney disease and sickle cell anemia. Aging Bioinformatics Complex Traits Computational Biology Genetics and Genomics Immune Disorders	Bar Harbor, ME	Aging\|Bioinformatics\|Complex Traits\|Computational Biology\|Genetics and Genomics\|Immune Disorders
The Anczukow Lab Principal Investigator Olga Anczuków-Camarda, Ph.D. Farmington, CT	Investigates how alternative RNA splicing contributes to cancer with the goal of identifying novel clinical biomarkers and targets for precision medicine. Genetics and Genomics Cancer	Farmington, CT	Genetics and Genomics\|Cancer
The Baker Lab Principal Investigator Christopher L. Baker, Ph.D. Bar Harbor, ME	Functional genomics and epigenetic modification	Bar Harbor, ME
The Beck Lab Principal Investigator Christine Beck, Ph.D. Farmington, CT	The Beck lab uses genomics, bioinformatics and molecular biological techniques to investigate the ways in which repetitive DNA elements, such as transposons, affect human genomes. Cancer Genetics and Genomics	Farmington, CT	Cancer\|Genetics and Genomics
The Blake Lab	Researches genome informatics with a focus on gene ontology. Genetics and Genomics Computational Biology Bioinformatics Resource Development and Dissemination Diabetes and Obesity Cancer Developmental Disorders Infectious Disease Research Neurodegenerative and Neuromuscular Diseases		Genetics and Genomics\|Computational Biology\|Bioinformatics\|Resource Development and Dissemination\|Diabetes and Obesity\|Cancer\|Developmental Disorders\|Infectious Disease Research\|Neurodegenerative and Neuromuscular Diseases
The Bloss Lab Principal Investigator Erik Bloss, Ph.D. Bar Harbor, ME	The Bloss Lab leverages high resolution imaging, observation and manipulation of in vivo neural activity, and genetic perturbations in specific neurons to define how neural circuits supports goal-directed behavior. Neurodegenerative and Neuromuscular Diseases Genetics and Genomics	Bar Harbor, ME	Neurodegenerative and Neuromuscular Diseases\|Genetics and Genomics
The Bolcun-Filas Lab Principal Investigator Ewelina Bolcun-Filas, Ph.D. Bar Harbor, ME	Researching meiosis, the mechanisms of DNA damage detection and repair during normal development of gametes, and implications for fertility of cancer patients after radiation and chemotherapy. Cancer Genetics and Genomics Reproductive Disorders	Bar Harbor, ME	Cancer\|Genetics and Genomics\|Reproductive Disorders
The Braun Lab Principal Investigator Robert E. Braun, Ph.D. Bar Harbor, ME	Investigating gamete development with a focus on spermatogenesis. Developmental Disorders Reproductive Disorders	Bar Harbor, ME	Developmental Disorders\|Reproductive Disorders
The Bult Lab Principal Investigator Carol Bult, Ph.D. Bar Harbor, ME	Bridging the digital biology divide, integrating computation with biomedical research. Computational Biology Genetics and Genomics Resource Development and Dissemination Cancer Developmental Disorders	Bar Harbor, ME	Computational Biology\|Genetics and Genomics\|Resource Development and Dissemination\|Cancer\|Developmental Disorders
The Burgess Lab Principal Investigator Robert Burgess, Ph.D. Bar Harbor, ME	Studies synapse development and function relevant to human neuromuscular disorders. Genetics and Genomics Neurodegenerative and Neuromuscular Diseases Developmental Disorders	Bar Harbor, ME	Genetics and Genomics\|Neurodegenerative and Neuromuscular Diseases\|Developmental Disorders
The Carter Lab Principal Investigator Gregory Carter, Ph.D. Bar Harbor, ME	Developing new computational strategies to understand complex genetic systems. Genetics and Genomics Computational Biology Bioinformatics Diabetes and Obesity Immune Disorders Cancer Reproductive Disorders Complex Traits	Bar Harbor, ME	Genetics and Genomics\|Computational Biology\|Bioinformatics\|Diabetes and Obesity\|Immune Disorders\|Cancer\|Reproductive Disorders\|Complex Traits
The Chang Lab Principal Investigator Chih-Hao "Lucas" Chang, Ph.D. Bar Harbor, ME	The Chang Lab delves into the intricate realm of immune cell metabolism and its profound impact on diseases like cancer and lupus, forging effective treatments through in-depth molecular understanding. Cancer Immune Disorders Infectious Disease Research Genetics and Genomics	Bar Harbor, ME	Cancer\|Immune Disorders\|Infectious Disease Research\|Genetics and Genomics
The Chesler Lab Principal Investigator Elissa J. Chesler, Ph.D. Bar Harbor, ME	Researches the genetics underlying behavior and identifies relationships among behavioral traits. Aging Behavioral Disorders Bioinformatics Complex Traits Computational Biology Genetics and Genomics Resource Development and Dissemination	Bar Harbor, ME	Aging\|Behavioral Disorders\|Bioinformatics\|Complex Traits\|Computational Biology\|Genetics and Genomics\|Resource Development and Dissemination
The Chuang Lab Principal Investigator Jeffrey Chuang, Ph.D. Farmington, CT	Analyzing sequence and assay data to better understand genome function. Genetics and Genomics Bioinformatics Computational Biology Cancer	Farmington, CT	Genetics and Genomics\|Bioinformatics\|Computational Biology\|Cancer
The Churchill Lab Principal Investigator Gary Churchill, Ph.D. Bar Harbor, ME	Investigating the genetics of health and disease with a systems approach. Computational Biology Complex Traits Genetics and Genomics Bioinformatics Aging Diabetes and Obesity	Bar Harbor, ME	Computational Biology\|Complex Traits\|Genetics and Genomics\|Bioinformatics\|Aging\|Diabetes and Obesity
The Cox Lab Principal Investigator Greg Cox, Ph.D. Bar Harbor, ME	Researches the molecular pathways of human degenerative muscle diseases. Genetics and Genomics Complex Traits Neurodegenerative and Neuromuscular Diseases Aging	Bar Harbor, ME	Genetics and Genomics\|Complex Traits\|Neurodegenerative and Neuromuscular Diseases\|Aging
The Dumont Lab Principal Investigator Beth Dumont, Ph.D. Bar Harbor, ME	Researching the mechanisms that generate genetic diversity through the lens of evolution. Complex Traits Computational Biology Genetics and Genomics Reproductive Disorders	Bar Harbor, ME	Complex Traits\|Computational Biology\|Genetics and Genomics\|Reproductive Disorders
The Handel Lab	Investigates the genetic regulation of meiosis and the mechanisms of male fertility to understand how errors in meiosis can lead to developmental abnormalities. Reproductive Disorders Developmental Disorders Genetics and Genomics		Reproductive Disorders\|Developmental Disorders\|Genetics and Genomics
The Harrison Lab Principal Investigator David E. Harrison, Ph.D. Bar Harbor, ME	Researches the genetics of aging and lifespan, seeking to understand the basic mechanisms of aging, and adult stem cells, with the goal of delaying normal aging processes.	Bar Harbor, ME
The Hinson Lab Principal Investigator J. Travis Hinson, M.D. Farmington, CT	Utilizing genomic approaches to interrogate mechanisms of inherited cardiovascular disorders. Genetics and Genomics	Farmington, CT	Genetics and Genomics
The Howell Lab Principal Investigator Gareth Howell, Ph.D. Bar Harbor, ME	Investigates the early stages of age-related neurodegenerative diseases. Genetics and Genomics Neurodegenerative and Neuromuscular Diseases Bioinformatics Aging	Bar Harbor, ME	Genetics and Genomics\|Neurodegenerative and Neuromuscular Diseases\|Bioinformatics\|Aging
The Jalili Lab Principal Investigator Sasan Jalili, Ph.D. Farmington, CT	The Jalili Research Group at The Jackson Laboratory (JAX) is focused on interrogating the host immunity, microbiome and their interface using different engineering tools in the context of infectious diseases, autoimmunity and cancer. Bioengineering Cancer Immune Disorders Infectious Disease Research	Farmington, CT	Bioengineering\|Cancer\|Immune Disorders\|Infectious Disease Research
The Joy Lab Principal Investigator Mary Teena Joy, Ph.D. Bar Harbor, ME	The Joy Lab is interested in understanding how circuits in the brain rewire after a stroke and other CNS injuries, with the goal of identifying molecular and circuit principles for recovery. Neurodegenerative and Neuromuscular Diseases	Bar Harbor, ME	Neurodegenerative and Neuromuscular Diseases
The Kaczorowski Lab	I lead a collaborative and interinstitutional research program that uses a multidisciplinary approach to identify early causative events underlying ‘normal’ nonpathological age-related memory decline and Alzheimer’s dementia.
The Korstanje Lab Principal Investigator Ron Korstanje, Ph.D. Bar Harbor, ME	Studies the genetics of kidney function and disease, particularly in the context of aging. Complex Traits Genetics and Genomics Aging Diabetes and Obesity	Bar Harbor, ME	Complex Traits\|Genetics and Genomics\|Aging\|Diabetes and Obesity
The Kumar Lab Principal Investigator Vivek Kumar, Ph.D. Bar Harbor, ME	We are a group of geneticists, neuroscientists, and computer scientists who are passionate about discoveries of novel targets and models for mental illness through innovation at the confluence of computational, genetic, and genomic methods. Genetics and Genomics Neurodegenerative and Neuromuscular Diseases Behavioral Disorders	Bar Harbor, ME	Genetics and Genomics\|Neurodegenerative and Neuromuscular Diseases\|Behavioral Disorders
The Lau Lab Principal Investigator Ching Lau, M.D., Ph.D. Farmington, CT	Using genomic technologies and mouse modeling including patient-derived xenografts (PDX) and genetically engineered mouse models (GEMM), we are discovering and validating novel biomarkers and therapeutic targets of pediatric cancers	Farmington, CT
The Lee Lab Principal Investigator Charles Lee, Ph.D., FACMG Farmington, CT	The Lee Lab studies structural genomic variation in human biology, evolution and disease. Bioinformatics Cancer Developmental Disorders Genetics and Genomics	Farmington, CT	Bioinformatics\|Cancer\|Developmental Disorders\|Genetics and Genomics
The Li Lab Principal Investigator Sheng Li, Ph.D. Farmington, CT	Assessing the performance of next-generation sequencing techniques in accurate genome/epigenome/transcriptome profiling and understanding the clinical and functional role of epigenome heterogeneity in the cancer evolution. Computational Biology Bioinformatics Aging Genetics and Genomics Cancer	Farmington, CT	Computational Biology\|Bioinformatics\|Aging\|Genetics and Genomics\|Cancer
The Liu Lab Principal Investigator Edison T. Liu, M.D. Farmington, CT	Researching the fundamental genomics of breast cancer. Genetics and Genomics Cancer	Farmington, CT	Genetics and Genomics\|Cancer
The Munger Lab Principal Investigator Steven Munger, Ph.D. Bar Harbor, ME	Steven Munger, Ph.D., uses a systems genetics approach and advanced computational methods to study development and complex disease in advanced mouse populations. Bioinformatics Genetics and Genomics	Bar Harbor, ME	Bioinformatics\|Genetics and Genomics
The Munnamalai Lab Principal Investigator Vidhya Munnamalai, Ph.D. Bar Harbor, ME	We investigate how signaling programs instruct in vivo stem cells of the cochlea to differentiate into a highly specialized, organized sensory epithelium.	Bar Harbor, ME
The Murray Lab Principal Investigator Steve Murray, Ph.D. Bar Harbor, ME	Investigating the genetic mechanisms of craniofacial development and developing new genetic tools and resources for the scientific community. Genetics and Genomics Resource Development and Dissemination	Bar Harbor, ME	Genetics and Genomics\|Resource Development and Dissemination
The Naggert Lab Principal Investigator Jürgen Naggert, Ph.D. Bar Harbor, ME	Investigates the genetics of metabolic syndrome and ciliopathies. Computational Biology Complex Traits Bioinformatics Diabetes and Obesity Developmental Disorders Genetics and Genomics Neurodegenerative and Neuromuscular Diseases	Bar Harbor, ME	Computational Biology\|Complex Traits\|Bioinformatics\|Diabetes and Obesity\|Developmental Disorders\|Genetics and Genomics\|Neurodegenerative and Neuromuscular Diseases
The Nishina Lab Principal Investigator Patsy Nishina, Ph.D. Bar Harbor, ME	Employs mouse models of human eye disease to study gene function and mechanisms underlying disease pathology. Genetics and Genomics Resource Development and Dissemination Complex Traits Behavioral Disorders Aging Diabetes and Obesity Developmental Disorders Neurodegenerative and Neuromuscular Diseases	Bar Harbor, ME	Genetics and Genomics\|Resource Development and Dissemination\|Complex Traits\|Behavioral Disorders\|Aging\|Diabetes and Obesity\|Developmental Disorders\|Neurodegenerative and Neuromuscular Diseases
The O'Connell Lab Principal Investigator Kristen M.S. O'Connell, Ph.D. Bar Harbor, ME	The overarching goal of my NIH-funded research program is to understand the neural control of appetite and how diet and body weight affect the excitability of the neurons in key CNS circuits responsible for food intake. Diabetes and Obesity Behavioral Disorders	Bar Harbor, ME	Diabetes and Obesity\|Behavioral Disorders
The Oh Lab Principal Investigator Julia Oh, Ph.D. Farmington, CT	The Oh Lab studies the human microbiome for its potential to deliver treatments for infectious and other diseases. (Image by Alex Valm, NHGRI) Genetics and Genomics Infectious Disease Research Bioinformatics	Farmington, CT	Genetics and Genomics\|Infectious Disease Research\|Bioinformatics
The Palucka Lab Principal Investigator Karolina Palucka, M.D., Ph.D. Farmington, CT	Studying the mechanisms of human immunity and developing cancer immunotherapies. Aging Immune Disorders Infectious Disease Research Cancer	Farmington, CT	Aging\|Immune Disorders\|Infectious Disease Research\|Cancer
The Paust Lab Principal Investigator Silke Paust, Ph.D. Farmington, CT	Members of the Paust laboratory are interested in the development and testing of novel immunotherapies that elicit clinically relevant Natural Killer cell-mediated anti-pathogen or anti-tumor immunity. Cancer Genetics and Genomics Immune Disorders Infectious Disease Research	Farmington, CT	Cancer\|Genetics and Genomics\|Immune Disorders\|Infectious Disease Research
The Pera Lab Principal Investigator Martin Pera, Ph.D. Bar Harbor, ME	Human pluripotent stem cells and the human embryo: Human pluripotent stem cells (hPSC) have opened up a previously inaccessible phase of the human life cycle to experimental study.	Bar Harbor, ME
The Peters Lab	Researches blood formation with a focus on red blood cells and the genetics underlying defects leading to anemias. Genetics and Genomics Complex Traits Aging		Genetics and Genomics\|Complex Traits\|Aging
The Reinholdt Lab Principal Investigator Laura Reinholdt, Ph.D. Bar Harbor, ME	Dr. Reinholdt’s research focuses on comparative and functional mammalian genomics, reproductive development and stem cell biology. Genetics and Genomics Complex Traits Resource Development and Dissemination Bioinformatics Reproductive Disorders Developmental Disorders	Bar Harbor, ME	Genetics and Genomics\|Complex Traits\|Resource Development and Dissemination\|Bioinformatics\|Reproductive Disorders\|Developmental Disorders
The Ren Lab Principal Investigator Guangwen "Gary" Ren, Ph.D. Bar Harbor, ME	To study tumor microenvironment and tumor immunology in cancer therapeutic resistance and metastatic relapse Cancer Aging Immune Disorders	Bar Harbor, ME	Cancer\|Aging\|Immune Disorders
The Ringwald Lab Principal Investigator Martin Ringwald, Ph.D. Bar Harbor, ME	Captures gene expression data and disseminates it to the research community. Bioinformatics Developmental Disorders Genetics and Genomics Resource Development and Dissemination	Bar Harbor, ME	Bioinformatics\|Developmental Disorders\|Genetics and Genomics\|Resource Development and Dissemination
The Robinson Lab Principal Investigator Peter Robinson, M.D., MSc. Farmington, CT	Develops algorithms and software for the analysis of exome and genome sequences. Skin Disease Computational Biology Genetics and Genomics	Farmington, CT	Skin Disease\|Computational Biology\|Genetics and Genomics
The Robson Lab Principal Investigator Paul Robson, Ph.D. Farmington, CT	The Robson lab utilizes advanced molecular, cellular, and stem cell biology approaches to study evolution, development, and disease relevant to the human condition.	Farmington, CT
The Roopenian Lab	Investigating the mechanisms of autoimmune disease to devise therapeutic approaches. Computational Biology Complex Traits Resource Development and Dissemination Immune Disorders Cancer Infectious Disease Research		Computational Biology\|Complex Traits\|Resource Development and Dissemination\|Immune Disorders\|Cancer\|Infectious Disease Research
The Rosenthal Lab Principal Investigator Nadia Rosenthal, Ph.D., FMedSci, FAAHMS Bar Harbor, ME	Investigating muscle development and its potential to regenerate after disease. Developmental Disorders Genetics and Genomics Aging Neurodegenerative and Neuromuscular Diseases	Bar Harbor, ME	Developmental Disorders\|Genetics and Genomics\|Aging\|Neurodegenerative and Neuromuscular Diseases
The Lee Lab Principal Investigator Se-Jin Lee, M.D., Ph.D. Farmington, CT	The overall focus of my research program has been to understand the molecular and cellular mechanisms underlying tissue growth and tissue regeneration with the long-term goal of developing new strategies for treating human diseases.	Farmington, CT
The Serreze Lab Principal Investigator David Serreze, Ph.D. Bar Harbor, ME	Investigating the genetic basis of autoimmunity and type 1 diabetes. Genetics and Genomics Immune Disorders Complex Traits Diabetes and Obesity	Bar Harbor, ME	Genetics and Genomics\|Immune Disorders\|Complex Traits\|Diabetes and Obesity
The Shultz Lab Principal Investigator Lenny Shultz, Ph.D. Bar Harbor, ME	Investigates human immunological diseases and malignancy through the development and leveraging of novel humanized mouse models Genetics and Genomics Resource Development and Dissemination Diabetes and Obesity Cancer Immune Disorders Infectious Disease Research	Bar Harbor, ME	Genetics and Genomics\|Resource Development and Dissemination\|Diabetes and Obesity\|Cancer\|Immune Disorders\|Infectious Disease Research
The Li Lab Principal Investigator Shuzhao Li, Ph.D. Farmington, CT	The application of high-resolution mass spectrometry now enables the measurement in human samples the metabolome, lipidome and small molecules of dietary, microbial and environmental origins. Bioinformatics Computational Biology Immune Disorders Resource Development and Dissemination	Farmington, CT	Bioinformatics\|Computational Biology\|Immune Disorders\|Resource Development and Dissemination
The Stitzel Lab Principal Investigator Michael Stitzel, Ph.D. Farmington, CT	Researches human pancreatic islet cells and the genetic and environmental bases of type 2 diabetes. Genetics and Genomics Bioinformatics Diabetes and Obesity Complex Traits Computational Biology	Farmington, CT	Genetics and Genomics\|Bioinformatics\|Diabetes and Obesity\|Complex Traits\|Computational Biology
The Tewhey Lab Principal Investigator Ryan Tewhey, Ph.D. Bar Harbor, ME	Our lab is focused on identifying and understanding the precise genetic mechanisms influencing human complex traits and risk to disease. To accomplish this our work spans several areas of interest. Bioinformatics Complex Traits Computational Biology Genetics and Genomics Immune Disorders	Bar Harbor, ME	Bioinformatics\|Complex Traits\|Computational Biology\|Genetics and Genomics\|Immune Disorders
The Trowbridge Lab Principal Investigator Jennifer Trowbridge, Ph.D. Bar Harbor, ME	Researches regulation of stem cells in the blood in normal development, aging and leukemia transformation. Genetics and Genomics Immune Disorders Cancer Aging	Bar Harbor, ME	Genetics and Genomics\|Immune Disorders\|Cancer\|Aging
The Ucar Lab Principal Investigator Duygu Ucar, Ph.D. Farmington, CT	Develops computational methods to study the epigenetic regulation of gene expression and its implications in important human conditions including aging and common diseases. Genetics and Genomics Computational Biology Bioinformatics Aging Immune Disorders	Farmington, CT	Genetics and Genomics\|Computational Biology\|Bioinformatics\|Aging\|Immune Disorders
The Unutmaz Lab Principal Investigator Derya Unutmaz, M.D. Farmington, CT	The Unutmaz Lab investigates the biology of the human immune system.	Farmington, CT
The Varn Lab Principal Investigator Frederick Varn, Ph.D. Farmington, CT	Integrates genomic and molecular pathology approaches to investigate how the tumor microenvironment drives development and treatment resistance in brain tumors Bioinformatics Computational Biology Cancer Genetics and Genomics	Farmington, CT	Bioinformatics\|Computational Biology\|Cancer\|Genetics and Genomics
The Wang Lab Principal Investigator Eric Wang, Ph.D. Farmington, CT	The Wang Laboratory at The Jackson Laboratory for Genomic Medicine is interested in understanding gene regulatory mechanisms that regulate leukemia survival, differentiation and therapy response. Cancer Genetics and Genomics	Farmington, CT	Cancer\|Genetics and Genomics
The West Lab Principal Investigator A. Phillip West, Ph.D. Bar Harbor, ME	The West Lab investigates how mitochondria shape immune and inflammatory responses in genetic disorders and aging-related diseases. Aging Cancer Immune Disorders Infectious Disease Research	Bar Harbor, ME	Aging\|Cancer\|Immune Disorders\|Infectious Disease Research