Cancer

Our Research Focus

C.C. Little established The Jackson Laboratory in 1929 to prove cancer is genetic, not infectious. He was right, of course, but little did he know that “genetic” only scratches the surface of cancer’s complexities. Recent research has revealed a dizzying number of changes to single genes, multiple genes, entire gene networks, genomic structures, genome repair and stability, etc., can contribute to malignant transformation, cancer maintenance, resistance to therapeutics, and cancer recurrence and spread.

The Jackson Laboratory has had a National Cancer Institute-designated cancer center since 1983, and our cancer research efforts are diverse and powerful. Our research program, “Genetic models for precision cancer medicine,” leverages our long-held expertise in model organism development and use, as well as our growing and technologically pioneering human cancer-genomics focus. We are driving research toward identifying precise clinical interventions to prevent cancers from progressing.

Faculty & Staff

Blaze Albert Lab Staff

Blaze Albert

Elaheh Alizadeh, Ph.D. Computational Scientist

Elaheh Alizadeh, Ph.D.

Olga Anczuków-Camarda, Ph.D. Associate Professor

Olga Anczuków-Camarda, Ph.D.

Kevin J. Anderson, Ph.D.

Kevin J. Anderson, Ph.D.

Peter Audano, III, Ph.D. Lab Staff

Peter Audano, III, Ph.D.

Cristina Baquero Mayo, Ph.D. Postdoctoral Associate

Cristina Baquero Mayo, Ph.D.

Abate Bashaw, Ph.D. Postdoctoral Associate

Abate Bashaw, Ph.D.

Christine Beck, Ph.D. Assistant Professor

Christine Beck, Ph.D.

David E. Bergstrom, Ph.D. Research Scientist

David E. Bergstrom, Ph.D.

Carol Bult, Ph.D. Professor

Carol Bult, Ph.D.

Xiurong Cai Postdoctoral Associate

Xiurong Cai

Alexander Calderon, Ph.D. Postdoctoral Associate

Alexander Calderon, Ph.D.

Vincent Caputo, Clinical Genomic Technologist Lab Staff

Vincent Caputo, Clinical Genomic Technologist

Gregory Carter, Ph.D. Professor

Gregory Carter, Ph.D.

Francisco Castellanos, M.S. Software Engineer

Francisco Castellanos, M.S.

Harshpreet Chandok, M.S. Bioinformatics/Data Analyst

Harshpreet Chandok, M.S.

Chih-Hao "Lucas" Chang, Ph.D. Assistant Professor

Chih-Hao "Lucas" Chang, Ph.D.

Chaojia Chen Postdoctoral Associate

Chaojia Chen

Jeffrey Chuang, Ph.D. Professor

Jeffrey Chuang, Ph.D.

Patricia Clow, Ph.D. Lab Staff

Patricia Clow, Ph.D.

Elise Courtois, Ph.D. Director, Research Scientist

Elise Courtois, Ph.D.

Maeva Devoucoux, Ph.D. Postdoctoral Associate

Maeva Devoucoux, Ph.D.

Ashok Dhinakaran Postdoctoral Associate

Ashok Dhinakaran

Sergii Domanskyi, Ph.D.

Sergii Domanskyi, Ph.D.

Alissa Dzis, MHI Lab Staff

Alissa Dzis, MHI

Ryan Englander Predoc

Ryan Englander

Bill Flynn, Ph.D. Lab Staff

Bill Flynn, Ph.D.

Ali Forougi Pour, Ph.D.

Ali Forougi Pour, Ph.D.

Zachary Frohock Bioinformatics/Data Analyst

Zachary Frohock

Mayuko Furuta, Ph.D. Associate Research Scientist

Mayuko Furuta, Ph.D.

Dolores Garcia-Arocena, Ph.D. Blogger

Dolores Garcia-Arocena, Ph.D.

Michael Gargano, B.S. Software Engineer

Michael Gargano, B.S.

Eva Gega, M.S. Lab Staff

Eva Gega, M.S.

Joanna Gell, M.D. Research Scientist

Joanna Gell, M.D.

Joshy George, Ph.D.

Joshy George, Ph.D.

Matthew Gerring, MEng Lab Staff, Software Engineer

Matthew Gerring, MEng

Ryan Gorham Lab Staff

Ryan Gorham

John P. Graham, Ph.D. Associate Research Scientist

John P. Graham, Ph.D.

Amit Gujar, Ph.D. Alumni

Amit Gujar, Ph.D.

Cuijuan Han, Ph.D. Postdoctoral Associate

Cuijuan Han, Ph.D.

Muneer Hasham, Ph.D. Research Scientist

Muneer Hasham, Ph.D.

Leslie Haynes Lab Staff

Leslie Haynes

Hao He, Ph.D.

Hao He, Ph.D.

Vishnu Hosur, Ph.D. Research Scientist

Vishnu Hosur, Ph.D.

Sasan Jalili, Ph.D. Assistant Professor, Lab Staff

Sasan Jalili, Ph.D.

Kevin C. Johnson, Ph.D. Research Scientist

Kevin C. Johnson, Ph.D.

Haebeen Jung, DVM, MS Lab Staff

Haebeen Jung, DVM, MS

Beena Kadakkuzha, Ph.D.

Beena Kadakkuzha, Ph.D.

Hyeongu Kang, Ph.D. Postdoctoral Associate

Hyeongu Kang, Ph.D.

Soo-Yeon Kang Lab Staff

Soo-Yeon Kang

Shilpita Karmakar, Ph.D.

Shilpita Karmakar, Ph.D.

Taushif Khan, Ph.D. Computational Scientist

Taushif Khan, Ph.D.

Teha Kim, Ph.D. Lab Staff

Teha Kim, Ph.D.

Orsolya Kiraly, Ph.D. Lab Staff

Orsolya Kiraly, Ph.D.

Debbie Krupke Scientific Curator

Debbie Krupke

Ching Lau, M.D., Ph.D. Professor

Ching Lau, M.D., Ph.D.

Raman Akinyanju Lawal, Ph.D.

Raman Akinyanju Lawal, Ph.D.

Donghyung Lee, Ph.D. Alumni

Donghyung Lee, Ph.D.

Charles Lee, Ph.D., FACMG Leadership, Professor

Charles Lee, Ph.D., FACMG

Sheng Li, Ph.D. Associate Professor

Sheng Li, Ph.D.

Edison T. Liu, M.D. Professor

Edison T. Liu, M.D.

Yang Liu, Ph.D. Associate Research Scientist

Yang Liu, Ph.D.

Hannah Megathlin Lab Staff

Hannah Megathlin

Efthymios Motakis, Ph.D.

Efthymios Motakis, Ph.D.

Lamis Naddaf, Ph.D. Postdoctoral Associate

Lamis Naddaf, Ph.D.

Steven Neuhauser Lab Staff, Software Engineer

Steven Neuhauser

Patrick Ng, Ph.D. Research Scientist

Patrick Ng, Ph.D.

Nooshin Nourbakhsh, Ph.D. Postdoctoral Associate

Nooshin Nourbakhsh, Ph.D.

Francis O'Neill, M.D., M.A. Postdoctoral Associate

Francis O'Neill, M.D., M.A.

Nélio Oliveira

Nélio Oliveira

Carolyn Paisie, Ph.D. Bioinformatics/Data Analyst

Carolyn Paisie, Ph.D.

Karolina Palucka, M.D., Ph.D. Professor

Karolina Palucka, M.D., Ph.D.

Ziwei Pan Predoc

Ziwei Pan

Blaine Pattavina, M.S. Lab Staff

Blaine Pattavina, M.S.

Silke Paust, Ph.D. Professor

Silke Paust, Ph.D.

Madison Pechulis

Madison Pechulis

Daniel Alfonso Peñarete, Ph.D. Postdoctoral Associate

Daniel Alfonso Peñarete, Ph.D.

Avijit Podder, Ph.D. Lab Staff

Avijit Podder, Ph.D.

Laura Reinholdt, Ph.D. Associate Professor

Laura Reinholdt, Ph.D.

Guangwen "Gary" Ren, Ph.D. Associate Professor

Guangwen "Gary" Ren, Ph.D.

Paul Robson, Ph.D. Professor

Paul Robson, Ph.D.

Nadia Rosenthal, Ph.D., FMedSci, FAAHMS Leadership, Professor

Nadia Rosenthal, Ph.D., FMedSci, FAAHMS

Wojciech Rosikiewicz, Ph.D. Alumni

Wojciech Rosikiewicz, Ph.D.

Jill Rubinstein, MD, Ph.D. Research Scientist

Jill Rubinstein, MD, Ph.D.

Jens Rueter, M.D. Director, Lab Staff

Jens Rueter, M.D.

Jennifer SanMiguel, Ph.D.

Jennifer SanMiguel, Ph.D.

Alan M. Sawyer, M.B.A. Director

Alan M. Sawyer, M.B.A.

Nick Sebasco, MS Software Engineer

Nick Sebasco, MS

Arunachalam Sekar, Ph.D. Postdoctoral Associate

Arunachalam Sekar, Ph.D.

Sayyed Hamed Shahoei, Ph.D. Lab Staff

Sayyed Hamed Shahoei, Ph.D.

Jiayuan Shi Lab Staff

Jiayuan Shi

Lenny Shultz, Ph.D. Professor

Lenny Shultz, Ph.D.

Santhosh Sivajothi, Ph.D. Research Scientist

Santhosh Sivajothi, Ph.D.

Daniel Skelly, Ph.D. Research Scientist

Daniel Skelly, Ph.D.

Antonios Somarakis Computational Scientist

Antonios Somarakis

Grace Stafford, Ph.D. Bioinformatics/Data Analyst

Grace Stafford, Ph.D.

Robert Straub, BS Lab Staff

Robert Straub, BS

Aaron Taylor, Ph.D. Postdoctoral Associate

Aaron Taylor, Ph.D.

Abdulfatai Tijjani, DVM, Ph.D. Postdoctoral Associate

Abdulfatai Tijjani, DVM, Ph.D.

Mohammed Toufiq

Mohammed Toufiq

Jarek Trapszo

Jarek Trapszo

Jennifer Trowbridge, Ph.D. Professor

Jennifer Trowbridge, Ph.D.

Frederick Varn, Ph.D. Assistant Professor

Frederick Varn, Ph.D.

Anita Voigt, Ph.D. Postdoctoral Associate

Anita Voigt, Ph.D.

Eric Wang, Ph.D. Assistant Professor

Eric Wang, Ph.D.

Etsuko Watanabe, Ph.D. Lab Staff

Etsuko Watanabe, Ph.D.

Julie Wells, Ph.D. Research Scientist

Julie Wells, Ph.D.

A. Phillip West, Ph.D. Associate Professor, Lab Staff

A. Phillip West, Ph.D.

Brian White, Ph.D.

Brian White, Ph.D.

John Wilson Lab Staff

John Wilson

Charlie Wray, Ph.D. Leadership

Charlie Wray, Ph.D.

Tina Wu, Ph.D. Associate Research Scientist

Tina Wu, Ph.D.

Kira Young, Ph.D. Associate Research Scientist

Kira Young, Ph.D.

Marina Yurieva, Ph.D. Lab Staff

Marina Yurieva, Ph.D.

Shanrong Zhang, Ph.D. Lab Staff

Shanrong Zhang, Ph.D.

Zi-Ming Zhao, Ph.D. Alumni

Zi-Ming Zhao, Ph.D.

Yue Zhao Computational Scientist

Yue Zhao

Upcoming Education

Upcoming Education
May 13 - 16
Workshop

Long-Read Sequencing Workshop

Precision medicine, Genetics and Genomics, Bioinformatics, Computational Biology
May 17 - 23
Workshop

Workshop on Techniques in Modeling Human Cancer in Mice

Endocrinology, Genetic Tools, Rare Diseases, Neurodegenerative Disease, Cancer/Tumors, Genetics and Genomics, Cancer
May 29 - 30
Short Course

The Whole Scientist Regional Short Course

Aging, Behavioral Disorders, Bioinformatics, Cancer, Computational Biology, Complex Traits, Developmental Disorders, Diabetes and Obesity, Eye Research, Genetics and Genomics, Immune Disorders, Skin Disease, Infectious Disease Research, Neurodegenerative and Neuromuscular Diseases, Reproductive Disorders, Resource Development and Dissemination
Jun10
Hybrid Event

Genome Technology Forum

Jul Aug 22 - 02
Short Course

Human and Mammalian Genetics and Genomics: The 65th McKusick Short Course

Precision medicine, Ethics, Stem cells, Microbiome, Infectious Disease, Immunology, Model Development, Rare Diseases, Aging, Cardiovascular, Cancer/Tumors, Developmental Biology, Diabetes, Genetic Tools, Optogenetics and Pharmacogenetics, Autoimmunity, Inflammation, Lupus, Addiction, Dermatology, Autoimmune Diseases Information, Metabolic Diseases, Neurodegenerative Disease, Reproductive Biology, Down Syndrome, Fragile X, Rett Syndrome, Neurodevelopmental Defects, Metabolic Defects, Cystic Fibrosis, Genetics and Genomics, Reproductive Disorders, Complex Traits, Developmental Disorders, Diabetes and Obesity, Neurodegenerative and Neuromuscular Diseases, Immune Disorders, Bioinformatics, Computational Biology, Cancer
Aug 04 - 12
Short Course

33rd Annual Short Course on Experimental Models of Human Cancer

Online Courses and On-Demand Webinars

Online Courses

Identifying Red Flags and Patterns That Increase Risk

Cancer/Tumors, Precision medicine, Cancer
Online Courses

Pre-test Decisions and Counseling

Cancer/Tumors, Precision medicine, Cancer, Genetics and Genomics
Online Courses

Using Family History to Inform Management

Cancer/Tumors, Colon and Rectal Cancer, Endometrial Cancer, Precision medicine, Cancer
Online Courses

Categorizing Cancer Risk

Cancer/Tumors, Precision medicine, Cancer, Genetics and Genomics
Online Courses

Interpreting Genetic Test Results

Cancer/Tumors, Precision medicine, Cancer, Genetics and Genomics
Online Courses

Genetic Testing for Colorectal Cancer Risk

Cancer/Tumors, Colon and Rectal Cancer, Precision medicine