Duygu Ucar, Ph.D.
Associate Professor
Develops computational models using genome datasets to study gene regulation and identify hypotheses for genomic medicine.
Next-generation sequencing technologies have revolutionized biological research and provided unique opportunities to study broad and novel questions about the regulation of gene expression. With these technologies, there has been an exponential increase in the types and amount of high-throughput datasets pertaining to the dynamics of gene expression. These data include gene expression data and genome-wide maps of nucleosome occupancy and open chromatin, epigenetic marks and transcription factor binding sites in cells and organisms under various experimental conditions. In my lab, we develop computational models to take advantage of genomics datasets to study the dynamics and mechanisms of transcriptional gene regulation and identify testable hypotheses for genomic medicine.
Visit the Ucar Personal Lab Site
Grants, honors and accomplishments
2009 - NSF Computing Innovation Postdoctoral Fellowship
2009 - Travel Award to attend International Society for Computational Biology conference ISMB
2009 - Travel Award to attend SIAM Data Mining Conference SDM
2007 - Best Applications Paper, ACM Knowledge Discovery and Data mining conference(Sig-KDD’2007)
2007 - Travel Award to attend Institute for Pure and Applied Mathematics (IPAM) workshop, UCLA
1998 - 2003 - Dean’s Honors, Bilkent University, Turkey,
1998 - 2003 - Full scholarship, Bilkent University, Turkey
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Research HighlightJanuary 05, 2024Investigating vaccine responses in older adults
Researchers at JAX and UConn Health are rigorously investigating why vaccines don’t work as well in some older adults. -
Research HighlightAugust 18, 2023Explaining long COVID and symptoms of prolonged inflammation
A new study by Weill Cornell Medicine and JAX could help explain symptoms of prolonged inflammation and long COVID in people who have had the disease. -
Research HighlightDecember 20, 2022Revealing the biology of senescent cells
JAX is playing a major role to bridge experimental mouse and human data and reveal the biology of senescent cells. -
Featured ArticleDecember 01, 2022Brooks Scholar Award propels cancer and aging research
Recipients of the 2022 Brooks Scholar Award represent a new generation of scientists whose research bridges the fields of cancer and aging.
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Press ReleaseDecember 19, 2023JAX's 2023 achievements
JAX is celebrating important research breakthroughs, new faculty and leadership appointments, and crucial advancements in legislation. -
Research HighlightMarch 14, 2023How does inflammation and aging tie to the AP-1 Complex?
JAX researchers reveal proteins from two families are consistently activated and likely play a role in promoting chronic inflammation with age. -
Press ReleaseDecember 19, 2022An outstanding year of growth at The Jackson Laboratory
2022 has been a notable year for The Jackson Laboratory, with great achievements and many reasons to celebrate continued momentum for JAX’s mission. -
Research HighlightFebruary 09, 2022Teaming up to predict influenza vaccine responses
Duygu Ucar of JAX is teaming up with infectious disease and aging experts to lead a study to understand influenza vaccine responsiveness in older adults.