Find genotyping protocols for your JAX® Mice strain.
NSG™ mice are a proven host for engraftment of human tumors or establishment of human immunity following hematopoietic stem cell transplantation. This guide explains why the interactions between human immune cells and tumors are paramount when devising treatment strategies that prevent tumor evasion of immune cells and improve cytotoxic responses.
This guide summarizes the guidelines for preclinical testing and colony management of ALS mice discusses considerations for preclinical studies using SOD1 mice, colony management, QPCR protocol for determining copy number, and more.
The definitive resource for anyone working with laboratory mice, this is the 6th edition of The Jackson Laboratory Handbook on Genetically Standardized Mice.
Humanized NSG™ mice are used by researchers and drug discovery scientists as powerful tools to study hematopoiesis, inflammatory disease and viral host-pathogen interactions. These mouse models are accelerating the development of novel therapies in HIV infection and oncology. This guide describes the development of humanized mice and how to select the appropriate model for your research