Farmington, CT
Areas of expertise include single cell transcriptomics, primate/human early embryonic development, maternal-fetal medicine, fetal programming, pluripotent cell biology, regulatory networks, tumor heterogeneity, circulating tumor cells.
Press Release
March 20, 2017
Single-cell signatures of colorectal tumors can provide more targeted diagnosis and treatment
Research Highlight
June 30, 2016
Circulating tumor cells in the blood of cancer patients have attracted intense scrutiny because of the potential they offer as easily accessible biomarkers and indicators of therapeutic response.
The Search Magazine Article
December 16, 2015
Recent advances in the techniques for isolating single cells, together with methods for amplifying their genetic material, now make it possible to explore the genomes of single cells.
Conventional thinking has been that Down syndrome phenotypes are caused by over-expression of trisomy chr 21 genes. However, gene under-expression is also partly to blame.
Research Highlight
August 22, 2016
Researchers describe an automated, high-throughput platform that allows simultaneous investigation of genotype, gene expression and DNA methylation at multiple locations in the genomes of single cells.
Muscle stem cells grown on an artificial scaffold in an optimized medium demonstrate preserved quiescence in vitro and enhanced proliferation and differentiation potency in vivo.
The Search Magazine Article
November 12, 2015
Biomedical science is capitalizing on various advances in tools and technology to explore and manipulate genomes. Three in particular are transforming medicine.
The Jackson Laboratory for Genomic Medicine and the University of Connecticut have signed an agreement to launch a joint Single Cell Genomics Center.