Key NASH Models
Comparison of the most popular and emerging models for non-alcoholic steatohepatitis (NASH) models
Leverage the world's largest collection of diabetes and obesity mouse models and more than 80 years of research expertise by using one of our metabolic disease strains for your investigations.
This poster compares the benefits and considerations for the top 10 metabolic disease mouse models from JAX.
Genetic alterations predispose mice to develop human-like diabetes phenotypes. However, overlooking the environmental factors that influence those phenotypes can confound research results.
In this series, we compare and contrast the top mouse models for metabolic diseases as well as discuss how these models recapitulate...
In this series, we compare and contrast the top mouse models for metabolic diseases as well as discuss how these models recapitulate...
A 2015 report demonstrates that sildenafil (Viagra®) treatment significantly alleviates diabetic peripheral neuropathy and neurovascular...
This poster compares the benefits and considerations for the top 10 metabolic disease mouse models from JAX.
Learn about the potential impact of the NntC57BL/6J mutation on studies related to diabetes and metabolism.
Retired JAX Laboratory scientist Douglas Coleman, Ph.D., who elegantly addressed complex biological problems, died at his...
Utilizing the most translationally-relevant in vivo model is crucial to generating meaningful data and getting a potential therapeutic...
Crown Bioscience selects JAX to distribute MS-NASH, a model that more closely mirrors human disease development.
The most direct method to test whether a specific genomic variant affects disease pathology is to introduce a corresponding mutation in the...
Three Connecticut research institutions are partnering with a prestigious counterpart in Israel to fill a research void that exists in the...
International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.
At the institution that first established the genetic and hormonal basis for obesity, JAX researchers probe for ways to prevent diabetes...
Metabolic phenotypes can vary among different strains. Comparisons are available to help you select the best model.
JAX® In Vivo Services examined the ability of the reference compound, rosiglitazone, to lower blood glucose and improve glucose tolerance....
NONcNZO10/LtJ (also known as RCS-10) males develop maturity-onset diabetes without the extreme weight gain characteristic of...