Key NASH Models
Comparison of the most popular and emerging models for non-alcoholic steatohepatitis (NASH) models
Leverage the world's largest collection of diabetes and obesity mouse models and more than 80 years of research expertise by using one of our metabolic disease strains for your investigations.
Comparison of the most popular and emerging models for non-alcoholic steatohepatitis (NASH) models
Detailed phenotypes for the most popular and newly emerging models of human type 2 diabetes & obesity.
Factors to consider when choosing diabetes and obesity mouse models
Comparison of the major type 2 diabetes and obesity phenotypes among humans and 7 widely used mouse models.
Metabolic phenotypes can vary among different strains. Comparisons are available to help you select the best model
Discover the Mouse Phenome Database and other online resources for type 2 diabetes and obesity research.
The streptozotocin (STZ) model of diabetes is available for C57BL/6J, NOD scid and NSG™ males. Protocols can be modified for other strains and sexes.
The National Center for Research Resources (NCRR) at NIH has funded a Type 1 Diabetes Resource at The Jackson Laboratory.
Models that may be used as tools in diabetes & obesity research.
This poster compares the benefits and considerations for the top 10 metabolic disease mouse models from JAX.
Genetic alterations predispose mice to develop human-like diabetes phenotypes. However, overlooking the environmental factors that influence those phenotypes can confound research results.
In this series, we compare and contrast the top mouse models for metabolic diseases as well as discuss how these models recapitulate...
In this series, we compare and contrast the top mouse models for metabolic diseases as well as discuss how these models recapitulate...
This poster compares the benefits and considerations for the top 10 metabolic disease mouse models from JAX.
Learn about the potential impact of the NntC57BL/6J mutation on studies related to diabetes and metabolism.
A 2015 report demonstrates that sildenafil (Viagra®) treatment significantly alleviates diabetic peripheral neuropathy and neurovascular...
Retired JAX Laboratory scientist Douglas Coleman, Ph.D., who elegantly addressed complex biological problems, died at his...
Utilizing the most translationally-relevant in vivo model is crucial to generating meaningful data and getting a potential therapeutic...
Three Connecticut research institutions are partnering with a prestigious counterpart in Israel to fill a research void that exists in the...
The most direct method to test whether a specific genomic variant affects disease pathology is to introduce a corresponding mutation in the...
International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.
Crown Bioscience selects JAX to distribute MS-NASH, a model that more closely mirrors human disease development.
I use quantitative approaches to unravel the genetic factors that underlie complex disease susceptibility. I develop and apply...
At the institution that first established the genetic and hormonal basis for obesity, JAX researchers probe for ways to prevent diabetes...
Metabolic phenotypes can vary among different strains. Comparisons are available to help you select the best model.
JAX® In Vivo Services examined the ability of the reference compound, rosiglitazone, to lower blood glucose and improve glucose tolerance....