The Adams Lab
The Adams lab develops new approaches for human and mouse microbiome analysis, seeks to understand the evolution of antibiotic resistance in Gram-negative pathogens, and contributes to clinical assay development for the JAX CLIA Laboratory.
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Genomic surveillance for SARS-CoV-2 variant
The CLIA R&D Team is supporting the genomic sequencing of SARS-CoV-2-positive cases to aid in understanding the changing distribution of viral lineages in Connecticut.
Microbial community profiling using high-plex targeted genomic assays
We have adapted a single-primer extension assay named “MA-GenTA” to quantitative profiling of bacteria in the mouse gut microbiome. Using this assay, we can determine the relative abundance of hundreds of microbial species at once. The assay is straightforward, cost-effective, and reproducible. Future work is directed at other applications of this method for characterizing the accessory genome variation and distribution of selected species.
Insertion sequence elements in Acinetobacter baumannii.
Insertion sequence (IS) elements have been major drivers of the spread of antibiotic resistance genes in A. baumannii and other bacteria. We are exploring the diversity of these elements and their contribution to genome evolution in this important nosocomial pathogen.
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Press ReleaseJune 21, 2021JAX center helps develop new genomic technology
JAX and principal investigator Mark Adams were chosen by the National Human Genome Research Institute to form the Technology Development Coordinating Center. The center will help accelerate genomics research through focused coordination and outreach programs. -
Press ReleaseJanuary 26, 2021Continued public testing urged during vaccine rollout
While Connecticut's vaccine rollout is progressing successfully, with the state ranking fifth nationally for the highest percent of the population vaccinated, continued public testing and caution are still more important than ever.
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Featured ArticleJune 16, 2021Is the Microbiome the Key to Your Health
Experts in the microbiome research field gathered during a recent JAXtaposition event hosted by The Jackson Laboratory to discuss the trillions of microorganisms including bacteria, viruses, and fungi that live within us, and how they contribute to health and disease.