The Pera Lab
Our laboratory has two main areas of research. We use human pluripotent stem cells to study extrinsic factors that regulate self-renewal, pluripotency and lineage specification during early human development. We also carry out functional genomic analyses in human and mouse pluripotent stem cells to identify genetic factors that influence regeneration and repair in the central nervous system. We are very pleased to be collaborating with the Nishina laboratory on a study of the genetics of macular degeneration, a common cause of blindness in the aging population.
The International Society for Stem Cell Research (ISSCR) is looking to fill a contract position for an Editorial Assistant for Stem Cell Reports, the official journal of the ISSCR. This position will provide administrative assistance to the Editor in Chief Professor Martin Pera and work closely with the Managing Editor.
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Research HighlightOctober 20, 2020From one cell to trillions: Exploring early development
JAX researchers are probing the mysteries of pluripotent stem cells; the earliest stages of life. -
Search MagazineJune 09, 2020Stroke researcher Cortes-Perez earns JAX Scholar Award
Dan Cortes-Perez, Ph.D., a postdoctoral associate studying neurological disorders at The Jackson Laboratory, has been awarded a JAX Scholar Award. -
Blog PostApril 21, 2020CD34+ Hematopoietic Stem Cell Humanized Mice: The Basics
Humanized mouse models serve as an innovative and cost-effective platform to simulate trials, evaluate multiple drugs alone or in combination, and produce predictive data. But, there are a number of questions that frequently arise with this model. Here are some of the more frequent questions and answers to using CD34+ hematopoietic stem cell humanized mice. -
Search MagazineAugust 09, 2019Unlocking the power of stem cells
Professor Martin Pera, Ph.D. combines his extraordinary expertise in human stem cell biology with powerful JAX resources in order to bring about breakthroughs in reproductive therapies and regenerative medicine.
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Search MagazineSeptember 07, 2020Mighty Mice stay mighty in space
In a paper published in the Proceedings of the National Academy of Sciences, researchers show that JAX Mighty Mice stayed relatively mighty during their time in microgravity, while the normal control mice lost considerable muscle mass and bone density. -
Research HighlightMay 15, 2020Improving stem cell cultures with ESR
Human pluripotent stem cells have enormous potential as research tools and as a platform for creating new therapies for intractable medical conditions. -
Search MagazineOctober 11, 2019Sherlock Holmes of the inner ear
JAX scientist Vidhya Munnamalai investigates the complex puzzle of cochlear development in an effort to cure hearing loss. -
Research HighlightJanuary 04, 2018
The state of the science in culturing totipotent stem cells
A review in the journal Cell Stem Cells by two JAX scientists reports on the latest efforts to isolate and culture the elusive populations of stem cells that most closely resemble very early (two-cell stage) totipotent cells.