To find out more about the complexities of inheritance, JAX spoke with author and New York Times columnist Carl Zimmer, who frequently writes about genetics and evolution. His new book, She Has Her Mother’s Laugh, tackles the vast concept of heredity – everything that living organisms pass on to future generations, and the means by which they do so.
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Inheriting a specific genetic variant, APOEε4, is linked with 15-20 percent rise in risk of developing Alzheimer’s, with at least 20 other genes implicated. JAX researchers are studying how APOEε4 risk depends on other genes, in mice with a wide variety of genetic backgrounds.
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Basile Tarchini, Ph.D., is working to understand the basic mechanisms underlying hair cell development, with the goal of restoring hearing following injury.
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New 3D bioprinting technique creates a platform for precision immunotherapy study.
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Associate Professor Greg Carter and his team are working at the intersection between patient and mouse research to develop accurate disease models of Alzheimer's disease and develop effective therapies.
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