Alzheimer’s disease (AD) is a major cause of dementia, disability and death in the elderly. Despite recent advances in our understanding of basic biological mechanisms...
NOD-scid IL2rgnull (NSG) and NOD-Rag1null IL2rgnull (NRG) mice support heightened levels of engraftment with human cells and tissues. These engrafted mice allow research on...
The Center for Systems Neurogenetics of Addiction (CSNA) aims to identify the biological relationships between the stages and patterns of cocaine addiction and behaviors that...
Resource lists and describes mouse models for ocular research at JAX.
Genetic Resource Science initiates and develops resource-generating research. Our team: identifies and implements innovative technologies for genetic research; makes and...
Integrating multi-track Hi-C data for genome-scale reconstruction of 3D chromatin structure
ATAC-seq is a new protocol to capture open chromatin sites by performing adaptor ligation and fragmentation of open chromatin regions. Due to its efficiency in requirement of...
To understand disease mechanisms and ultimately develop effective therapies for AD, it is essential we apply state-of-the-art approaches to generate...
The Jackson Laboratory Cancer Center (JAXCC) is a National Cancer Institute-designated Cancer Center complemented by institutional education, resource and service initiatives...
The JAX Cre Repository's aim is to provide the scientific community with a centralized, comprehensive set of well-characterized Cre-driver lines and related information...
In this project we will create mice carrying the human pathogenic mutations identified by our collaborators. The mutations will be introduced onto both a standard, stable...
Scientists around the world are working to generate a targeted knockout mutation for every gene in the mouse genome through the Knockout Mouse...
MAV-seq (Management, Analysis, Visualization of Sequence data) is an interactive, user friendly, cross platform, secure, encrypted, automated, customized, centralized,...
International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.
Mice harboring spontaneous mutations have long been a major source for animal models of human genetic disorders, particularly mendelian diseases. The Mouse Mutant Resource...
This resource provides mouse models for facial, dental, eye, ear and skull development research, as well as mouse models of human craniofacial...
Our goal is to focus our diverse expertise in biology and genomics on the problems and disorders associated with aging.
The Parkinson’s Disease Mouse Model Resource characterizes and distributes new mouse models of Parkinsonism and Parkinson’s disease.
The center enables scientists to harness the full power of genomic technologies and computational strategies and use them to analyze the human genome to discover new and...
The SMSR maintains mice that are important tools for genetic analysis of complex diseases, including consomic strains.
