To assess how microbial species are derived and their importance, a team led by JAX Assistant Professor Julia Oh took a hard look at the dynamics of strain diversity for a specific bacterium in human skin, Staphylococcus (S.) epidermidis.
Maintaining experimental mouse colonies is a lot like juggling. There are a lot of balls that you have to keep in the air all the time. You need to evaluate the breeding performance, adjust the colony size to match required production, genotype the mice, and then plan and execute your experiments. It is easy to have concerns about genetic drift far down on your list of priorities. However, for mutant or transgenic mouse strains on inbred backgrounds dealing with potential genetic drift needs to be a priority.