The Dumont Lab
Researching the mechanisms that generate genetic diversity through the lens of evolution
Principal Investigator
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Our Research Focus
The broad objective of my research program is to understand the causes and consequences of variation in the cellular mechanisms that govern DNA inheritance: genetic recombination, chromosome segregation, and de novo mutation. To date, my work has combined wet-bench and computational approaches in multiple mammalian model systems to investigate variation in two recombination mechanisms, crossing-over and gene conversion. Over the next several years, my research group will work at the leading edge of genomics, evolutionary genetics, and cytogenetics to advance our understanding of recombination rate variation from diverse biological perspectives.
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Press ReleaseMay 11, 2021Heligenics, JAX collaborating on ERBB2 breast cancer gene
Includes licensing of custom Heligenics Gene Mutation/Function ERBB2 library for the JAX Clinical Knowledgebase. -
Blog PostApril 26, 2021Using the power of sequencing on our smallest organisms
The microbiome plays a vital role in our health and wellbeing. Now researchers are using sequencing technology to better understand it. -
Press ReleaseApril 13, 2021Shriners Hospitals for Children and JAX announce research affiliation
A new research affiliation agreement between Shriners Hospitals for Children (SHC) and JAX will endeavor to gain a greater understanding of the genetic factors involved in cerebral palsy. -
Research HighlightApril 12, 2021New research asks how bone marrow affects us as we age
New research done by JAX scientists investigates how bone marrow affects our health as we age.
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Featured ArticleMay 06, 2021Microscopic powerhouses: what are organoids?
One of the most significant scientific advances of the last ten years, organoids have revolutionized research across several fields, and continue to grow more advanced and helpful year over year. So, what are these microscopic powerhouses, exactly? -
Research HighlightApril 15, 2021New insights into ecDNA function advances cancer research
JAX researchers report in Cancer Cell further insight into yet another way extrachromosomal, circular DNA (ecDNA) may promote cancer. -
Search MagazineApril 13, 2021
Cancer dangers hidden in plain sight
In the hunt for genetic cancer risk factors, researchers painstakingly analyze huge amounts of genome sequence data. -
Research HighlightApril 05, 2021Using machine learning to analyze mouse behavior
JAX researcher Dr. Vivek Kumar trains computers (using machine learning) to analyze specific mouse behaviors.