Jackson Laboratory

The Dumont Lab

Principal Investigator: Beth Dumont, Ph.D.

The Jackson Laboratory
Bar Harbor, ME

Contact me at: 207-288-6647

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Researching the mechanisms that generate genetic diversity through the lens of evolution

Our Research Focus

The broad objective of my research program is to understand the causes and consequences of variation in the cellular mechanisms that govern DNA inheritance: genetic recombination, chromosome segregation, and de novo mutation. To date, my work has combined wet-bench and computational approaches in multiple mammalian model systems to investigate variation in two recombination mechanisms, crossing-over and gene conversion. Over the next several years, my research group will work at the leading edge of genomics, evolutionary genetics, and cytogenetics to advance our understanding of recombination rate variation from diverse biological perspectives.

Full Scientific Report

Research HighlightSeptember 11, 2018
Exploring zinc finger proteins
The National Institute of General Medical Sciences has awarded Petko Petkov a four-year grant totaling $1,385,337 to exploit the new methods he has developed to profile and investigate zinc finger proteins and their binding sites.
Search MagazineAugust 14, 2018
Understanding our inheritance
To find out more about the complexities of inheritance, JAX spoke with author and New York Times columnist Carl Zimmer, who frequently writes about genetics and evolution.
Press ReleaseAugust 01, 2018
$2M NIH Grant to Study Genetic Mechanisms of Inherited Heart Muscle Disorders
Travis Hinson, M.D., has received more than $2 million from the National Institutes of Health National Heart, Lung, and Blood Institute to study the mechanisms responsible for a serious and often fatal heart condition.
- Cardiovascular
- Genetics and Genomics
Minute to UnderstandingJune 28, 2018
What is epigenetics?
Learn how epigenetic changes can affect an individual without physically changing their DNA sequence.
- Aging
- Genetics and Genomics

Search MagazineSeptember 11, 2018
Non-coding DNA is not junk after all
Assistant Professor Christine Beck, Ph.D., is uncovering how recurring sequences in our genomes might shed light on genome stability, as well as diseases like cancer.
Press ReleaseAugust 01, 2018
A RACIPE for success
New five-year, $2.2M outstanding investigator grant to Mingyang Lu will support systems biology algorithm approach.
Research HighlightJuly 12, 2018
The distinct forms of an important genomic disruption
A new paper further explains the genomic disruption known as the tandem duplicator phenotype (TDP), a common attribute in some of the most deadly cancers of women.
Research HighlightJune 21, 2018
Finding the genes controlling ovarian reserve could hold key to better female fertility care
Jackson Laboratory Assistant Professor Ewelina Bolcun-Filas, Ph.D., is looking at how multiple genetic factors regulating oocyte development determine the differences in each woman’s ovarian reserve.

Lab Staff

Uma Arora

PhD Student

Investigating the composition and diversity of centromeric sequence amongst Mus musculus subspecies and autosomes vs sex chromosomes to understand their significance in evolution.
Beth Dumont, Ph.D.

Assistant Professor
Brett Haines, B.S.

Research Assistant

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Open Positions

Job	Job Title	Location	Description

Selected Publications

View full list of publications