The Dumont Lab
Researching the mechanisms that generate genetic diversity through the lens of evolution
Principal Investigator
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Our Research Focus
The broad objective of my research program is to understand the causes and consequences of variation in the cellular mechanisms that govern DNA inheritance: genetic recombination, chromosome segregation, and de novo mutation. To date, my work has combined wet-bench and computational approaches in multiple mammalian model systems to investigate variation in two recombination mechanisms, crossing-over and gene conversion. Over the next several years, my research group will work at the leading edge of genomics, evolutionary genetics, and cytogenetics to advance our understanding of recombination rate variation from diverse biological perspectives.
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Research HighlightMay 05, 2022Investigating the non-coding genome
Ryan Tewhey, Ph.D., is leading efforts to apply high-throughput analyses to understand both how non-coding genome regulation works and its many roles in disease. -
Press ReleaseMay 05, 2022JAX and the Roux Institute are building a biotech workforce
The Jackson Laboratory’s Bar Harbor campus was home base for the Roux Institute at Northeastern University’s Biotechnology Applied Lab course. Trainees in attendance are Master of Science in Biotechnology students at the Roux Institute. -
Press ReleaseMay 03, 2022JAX announces 2022 recipients of the JAX Scholar awards
The Jackson Laboratory is proud to announce the 2022 recipients of the JAX Postdoctoral Scholar award. Eric Bogenschutz, Jayna Mistry, and Kwondo Kim represent forward-thinking research, proven leadership, and engagement with the scientific community. -
Search MagazineApril 26, 2022Using machine learning to keep an eye on healthy function and disease
JAX scientist Vivek Kumar, Ph.D., is using machine learning to automate and improve analysis of mouse behavior and movement. The new methods have already yielded important biological insights, and they may have even more profound implications for research into human diseases such as ALS, Alzheimer’s disease, and even cancer.
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Featured ArticleMay 05, 2022Ryan Tewhey: Genome explorer
JAX's Ryan Tewhey brings open-minded inquiry to the search for genetic mechanisms involved in complex traits and disease mechanisms. -
Featured ArticleMay 04, 2022Putting machine learning to work for cancer patients
A research team at JAX is boosting the speed and accuracy of tumor sample image analysis, for multiple cancer types, offering the potential for more targeted treatment direction without additional testing. -
Profile StoryApril 27, 2022Data analyst visualizes life inside cells
A spotlight profile of Martine Seignon, a research data analyst specializing in data visualization in the Single Cell Biology Laboratory based at The Jackson Laboratory for Genomic Medicine in Farmington, Conn. -
Research HighlightApril 20, 2022Fibroblasts may hold the keys to regeneration
New research from JAX indicates that fibroblasts may hold the ability to jump start human tissue repair and regeneration capabilities.