Researching the mechanisms that generate genetic diversity through the lens of evolution
The broad objective of my research program is to understand the causes and consequences of variation in the cellular mechanisms that govern DNA inheritance: genetic recombination, chromosome segregation, and de novo mutation. To date, my work has combined wet-bench and computational approaches in multiple mammalian model systems to investigate variation in two recombination mechanisms, crossing-over and gene conversion. Over the next several years, my research group will work at the leading edge of genomics, evolutionary genetics, and cytogenetics to advance our understanding of recombination rate variation from diverse biological perspectives.
Researching the mechanisms that generate genetic diversity through the lens of evolution
This two-day course will help emerging scientists equip themselves with the professional, interpersonal and communication skills that...
A stable iPSC line, KOLF2.1J, has been established to act as a high-quality baseline platform for modeling human disease.
JAX is playing a major role to bridge experimental mouse and human data and reveal the biology of senescent cells.
Cellular senescence in the developing human placenta; discovery and validation of novel placental biomarkers to characterize placental cell...
Professor Nadia Rosenthal is the inaugural chairholder of the The Maxine Groffsky Endowed Chair, made possible through a...
Learn about how cancer is formed in this Minute to Understanding video from The Jackson Laboratory.
Learn about DNA changes in this Minute to Understanding from The Jackson Laboratory.
Discover how PDX mouse models are changing the field of personalized medicine.
A group led Ryan Tewhey and Kousuke Mouri developed a method to detect silencer activity at a genome-wide scale to address the imbalance...
To study the evolution of genes related to fertility and sexual reproduction, and to use this information to understand infertility in...