The Rosenthal Lab
Global leader in the use of targeted mutagenesis in mice to investigate muscle development, disease and repair.
Principal Investigator
Topics
Rosenthal’s research uses mammalian genetics to explore the embryonic development of heart and skeletal muscle and the regeneration of adult tissues. She focuses on muscle and cardiac developmental genetics and the role of growth factors, stem cells and the immune system in tissue regeneration.
She is a global leader in the use of targeted mutagenesis in mice to investigate muscle development, disease and repair, and is a participant in EUCOMM, the European Conditional Mouse Mutagenesis Program, where she coordinates the selection and production of new Cre driver strains for the international mouse genetics community.
Featured Coverage
- Long-COVID and Diversity - Springer Nature has published an article regarding finding ways to study long-COVID, the challenging diversity of symptoms that people experience after recovering from COVID-19, featuring Rosenthal.
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Research HighlightMay 09, 2023Variability in the earliest stages of development
The processes enabling pluripotency at the very beginning of life are more different between mouse strains than you might expect. -
Research HighlightApril 27, 2023Uncovering the genetic secrets behind human uniqueness
Ryan Tewhey is part of a research group that identified and characterized more than 10,000 human-specific Conserved Deletions (hCONDELs) enriched for brain functions. The findings will be important for further investigation of the evolutionary mechanisms that produce the traits that distinguish humans from other species. -
Research HighlightApril 11, 2023Churchill Lab performs multi-omics study on protein phosphorylation regulators
The Churchill lab performed an integrative multi-omics analysis of 58 genetically diverse Collaborative Cross strains to identify regulators of protein phosphorylation. -
Featured ArticleApril 05, 2023Advancing genetics education in Memphis
Teaching the Genome Generation has expanded to the Memphis Shelby County School District, offering high school teachers and students enhanced genetics and genomics education.
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Blog PostMay 04, 2023JAX Genomic Education leads DNA Day 2023 celebrations
JAX Genomic Education joined the global celebration of all things genetics across JAX campuses, online, and in our communities. -
Research HighlightApril 25, 2023Unraveling exercise's impact on brain health
Erik Bloss has received a $3.9M R01 to study neurological changes in response to exercise and the role specific neurons in the brain. -
Research HighlightApril 05, 2023Exploring genetic diversity in mouse strains
Christine Beck led a team that explored mouse genome, and revealed details across 20 diverse inbred strains that will be critical for informing mouse-based genetics and genomics research moving forward. -
Press ReleaseApril 04, 2023Mitchell Kennedy to lead JMCRS
Mitchell (Mitch) Kennedy joins JAX as executive vice president, JAX and president, JAX® Mice, Clinical and Research Services (JMCRS).