Jackson Laboratory

The Rosenthal Lab

Principal Investigator: Nadia Rosenthal, Ph.D., F.Med.Sci

The Jackson Laboratory
Bar Harbor, ME

Global leader in the use of targeted mutagenesis in mice to investigate muscle development, disease and repair.

Rosenthal’s research uses mammalian genetics to explore the embryonic development of heart and skeletal muscle and the regeneration of adult tissues. She focuses on muscle and cardiac developmental genetics and the role of growth factors, stem cells and the immune system in tissue regeneration.

She is a global leader in the use of targeted mutagenesis in mice to investigate muscle development, disease and repair, and is a participant in EUCOMM, the European Conditional Mouse Mutagenesis Program, where she coordinates the selection and production of new Cre driver strains for the international mouse genetics community.

Lab Staff

Zachery Beal

Research Assistant I

Regenerative Research
Jane Branca

Biomedical Technologist III
Mauro Costa, Ph.D.

Research Scientist

Studies congenital heart disease and the complex interplay between genetic predisposition and cardiac stress mediated by obesity, high blood pressure and myocardial infarction.
Elvira Forte, Ph.D.

Research Assistant IV

Employs mouse genetic models to study the role of stromal cells in cardiac development and in scar formation in response to ischemic injury.
Milena B. Furtado, M.Sc., Ph.D.

Associate Research Scientist

Broad research interests include the study of organ fibrosis, and more specifically, heart fibrosis, using mouse genetic models.
John P. Graham, Ph.D.

Associate Research Scientist

I am interested in the intersection of tissue regeneration, cancer, and the mammalian immune system.
Muneer Hasham, Ph.D.

Research Scientist

Wide array of research interests includes infectious diseases, immune disorders and cancer pathogenesis. He also has an interest in developing and streamlining biological protocols and processes.
Mike McLellan

Ph.D. Student

Studies cell type diversity in the heart and its role in repair after injury.
Raghav Pandey, Ph.D.

Postdoctoral Associate

Cardiovascular research focused on metabolic changes that can be altered to prevent disease onset.
Nadia Rosenthal, Ph.D., F.Med.Sci

Scientific Director and Professor, The Jackson Laboratory for Mammalian Genetics

Global leader in the use of targeted mutagenesis in mice to investigate muscle development, disease and repair.

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Open Positions

Job	Job Title	Location	Description

Selected Publications

View full list of publications

Research HighlightSeptember 11, 2018
Exploring zinc finger proteins
The National Institute of General Medical Sciences has awarded Petko Petkov a four-year grant totaling $1,385,337 to exploit the new methods he has developed to profile and investigate zinc finger proteins and their binding sites.
Press ReleaseSeptember 05, 2018
A better combination therapy for leukemias
A new approach to treating some leukemias could deliver a one-two punch to the cancer cells without harming normal tissue.
Search MagazineAugust 08, 2018
Patient by patient: Finding cures for rare diseases
Four years ago as part of The Burgess Lab at The Jackson Laboratory, Kathy Morelli and a large team of collaborators took on the challenge of creating a cure for Caroline, a young girl who was battling an incurable disease called Charcot-Marie-Tooth.
Press ReleaseJuly 26, 2018
Alzheimer’s disease: The diet-gene connection
New $3.8M National Institute on Aging grant will fund JAX studies of hypothalamic dysfunction in Alzheimer’s.
- Alzheimer's Disease
- Neurodegenerative and Neuromuscular Diseases

Search MagazineSeptember 11, 2018
Non-coding DNA is not junk DNA
Assistant Professor Christine Beck, Ph.D., is uncovering how recurring sequences in our genomes might shed light on genome stability, as well as diseases like cancer.
Search MagazineAugust 14, 2018
Understanding our inheritance
To find out more about the complexities of inheritance, JAX spoke with author and New York Times columnist Carl Zimmer, who frequently writes about genetics and evolution.
Press ReleaseAugust 01, 2018
$2M NIH Grant to Study Genetic Mechanisms of Inherited Heart Muscle Disorders
Travis Hinson, M.D., has received more than $2 million from the National Institutes of Health National Heart, Lung, and Blood Institute to study the mechanisms responsible for a serious and often fatal heart condition.
- Cardiovascular
- Genetics and Genomics
Research HighlightJuly 23, 2018
$2.4 million grant to JAX for strategies to extend healthy function of blood and immune systems during aging
The five-year grant enables studies exploring ways to boost the hematopoietic system for better regenerative capacity, immune cell function during aging.
- Aging
- Aging