The Rosenthal Lab
Global leader in the use of targeted mutagenesis in mice to investigate muscle development, disease and repair.
Principal Investigator
Topics
Rosenthal’s research uses mammalian genetics to explore the embryonic development of heart and skeletal muscle and the regeneration of adult tissues. She focuses on muscle and cardiac developmental genetics and the role of growth factors, stem cells and the immune system in tissue regeneration.
She is a global leader in the use of targeted mutagenesis in mice to investigate muscle development, disease and repair, and is a participant in EUCOMM, the European Conditional Mouse Mutagenesis Program, where she coordinates the selection and production of new Cre driver strains for the international mouse genetics community.
Featured Coverage
- Long-COVID and Diversity - Springer Nature has published an article regarding finding ways to study long-COVID, the challenging diversity of symptoms that people experience after recovering from COVID-19, featuring Rosenthal.
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Research HighlightSeptember 28, 2022Tipping the scale toward favorable outcomes in cancer and beyond
Jennifer Trowbridge and her team reveal the molecular signaling pathway most associated with clonal hematopoiesis and how blocking a specific cell-surface receptor in the pathway can tip the balance toward positive health outcomes. -
Research HighlightSeptember 08, 2022Measuring frailty in mice to examine aging
Vivek Kumar is using machine learning and computational science to examine frailty in mice to study the biology of aging. -
Featured ArticleSeptember 06, 2022Connecting life-long dietary restrictions and loss of cognitive function
Andrew Ouellette is helping to discover new connections between life-long dietary restriction and the loss of cognitive function. -
Research HighlightJuly 21, 2022Investigating endometriosis, cell by cell
Many women worldwide are affected by endometriosis, though there has been relatively little research into causes or possible therapies. Elise Courtois, associate director of the Single Cell Biology group at The Jackson Laboratory, is a leading proponent for increasing awareness of and funding for endometriosis.
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Featured ArticleSeptember 15, 2022JAX undertakes nationwide study to evaluate impact of genomic tumor boards on cancer care
The Jackson Laboratory announced today that it will take its cornerstone genomic tumor board program to oncologists across the nation as part of a SWOG Cancer Research Network study, in collaboration with Columbia University. -
Featured ArticleSeptember 06, 2022Developing machine learning and deep learning at JAX
Matthew Gerring is applying the machine learning and deep learning revolution at JAX. -
Press ReleaseAugust 31, 2022Peter Robinson to serve on NHGRI Advisory Council
Peter Robinson of the Jackson Laboratory was sworn in to the National Human Genome Research Institute’s (NHGRI) Advisory Council on Aug 19, 2022. -
Featured ArticleJuly 06, 2022Donors contribute more than $7.6M to vision research at JAX
JAX has recently received more than $7.6 million in philanthropic investment to support vision research.