Researches regulation of stem cells in the blood in normal development, aging and leukemia transformation.
The Trowbridge laboratory studies cell fate regulation within the hematopoietic system. Our current focus is on the epigenetic regulation of hematopoietic stem cell (HSC) and progenitor cell lineage commitment in three contexts: (1) normal blood development and maintenance, (2) alterations that occur during the process of aging, and (3) alterations that occur during the process of transformation giving rise to leukemia. Our ultimate goal is to reveal epigenetic patterns and processes that are uniquely deregulated during aging and/or transformation, which can be used to identify novel biomarkers of disease and targets for development of therapeutics.
Dana-Farber Cancer Institute
Postdoctoral fellow, hematology
2012
University of Western Ontario
Ph.D., microbiology & immunology
2006
University of Western Ontario
B.S., genetics
2002
Tufts University
Adjunct Faculty
2012-present
The Jackson Laboratory
Assistant Professor
2012-present
University of Maine
Adjunct Faculty at the Graduate School of Biomedical Sciences
2012-present
Harvard Medical School
Instructor in Pediatrics
2011-2012
Harvard Medical School
Research Fellow in Pediatrics
2006-2011
Ellison Medical Foundation New Scholar Award in Aging
2013-present
American Society of Hematology (ASH) Scholar Award
2011-2013
Leukemia & Lymphoma Society Career Development Program Fellowship
2007-2010
Poland Award for Top Graduating Ph.D. Student
2006-2007
National Cancer Institute of Canada (NCIC) Research Studentship
2005-2007
Ontario Graduate Society (OGS) Studentship
2002-2003