Jennifer Trowbridge, Ph.D.
Associate Professor, The Dattels Family Chair
Researches regulation of stem cells in the blood in normal development, aging and leukemia transformation.
The Trowbridge laboratory studies cell fate regulation within the hematopoietic system. Our current focus is on the epigenetic regulation of hematopoietic stem cell (HSC) and progenitor cell lineage commitment in three contexts: (1) normal blood development and maintenance, (2) alterations that occur during the process of aging, and (3) alterations that occur during the process of transformation giving rise to leukemia. Our ultimate goal is to reveal epigenetic patterns and processes that are uniquely deregulated during aging and/or transformation, which can be used to identify novel biomarkers of disease and targets for development of therapeutics.
Education and experience
Education
Dana-Farber Cancer Institute
Postdoctoral fellow, hematology
2012
University of Western Ontario
Ph.D., microbiology & immunology
2006
University of Western Ontario
B.S., genetics
2002
Experience
Tufts University
Adjunct Faculty
2012-present
The Jackson Laboratory
Assistant Professor
2012-present
University of Maine
Adjunct Faculty at the Graduate School of Biomedical Sciences
2012-present
Harvard Medical School
Instructor in Pediatrics
2011-2012
Harvard Medical School
Research Fellow in Pediatrics
2006-2011
Grants, Honors, and Accomplishments
Ellison Medical Foundation New Scholar Award in Aging
2013-present
American Society of Hematology (ASH) Scholar Award
2011-2013
Leukemia & Lymphoma Society Career Development Program Fellowship
2007-2010
Poland Award for Top Graduating Ph.D. Student
2006-2007
National Cancer Institute of Canada (NCIC) Research Studentship
2005-2007
Ontario Graduate Society (OGS) Studentship
2002-2003
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Research HighlightSeptember 28, 2022Tipping the scale toward favorable outcomes in cancer and beyond
Jennifer Trowbridge and her team reveal the molecular signaling pathway most associated with clonal hematopoiesis and how blocking a specific cell-surface receptor in the pathway can tip the balance toward positive health outcomes. -
Press ReleaseMay 03, 2022JAX announces 2022 recipients of the JAX Scholar awards
The Jackson Laboratory is proud to announce the 2022 recipients of the JAX Postdoctoral Scholar award. Eric Bogenschutz, Jayna Mistry, and Kwondo Kim represent forward-thinking research, proven leadership, and engagement with the scientific community. -
Search MagazineOctober 06, 2021A lifelong friendship inspires support for JAX blood cancer research
A lifelong friendship inspires support for JAX blood cancer research. -
Search MagazineSeptember 08, 2021Researching why and how we age
The Nathan Shock Centers of Excellence is empowering innovative approaches to aging research.
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Featured ArticleSeptember 13, 2022The Dattels Family Chair - Powering Leukemia Research at JAX
Associate professor Jennifer Trowbridge, Ph.D., whose laboratory at JAX’s Bar Harbor campus focuses on the study of cellular changes that can lead to leukemia, has been appointed as the inaugural Dattels Family Chair. -
Research HighlightDecember 13, 2021Examining the immune response to cancer on a genetic level
The V Foundation for Cancer Research has awarded a grant to JAX's Lucas Chang for genetic studies of the immune response to cancer. -
Research HighlightOctober 05, 2021Discovering how to prevent aging and cancer in the blood cell system
Jennifer Trowbridge of JAX seeks to thwart the mutations and inflammation that accumulate in aging bone marrow to maintain production of healthy blood cells and reduce blood cancer risk. -
Research HighlightApril 12, 2021New research asks how bone marrow affects us as we age
New research done by JAX scientists investigates how bone marrow affects our health as we age.