Lab equipment and reagents described in these protocols will be provided by JAX to teachers who are currently teaching in a New England state and who have participated in our Teaching the Genome Generation (TtGG) professional development program. Learn more here.
Students practice accurately micropipetting volumes of colored water to make a six-color rainbow from only three primary colors.
DNA Extraction begins the genotyping experiment.
PCR allows for the amplification of specific DNA sequences from a very small starting amount of DNA.
Restriction enzymes cut DNA at specific sequences, which can aid in genotyping samples.
Gel electrophoresis is the process by which fragments of DNA in a sample are separated by size.
Sequence analysis on DNA can identify single nucleotide polymorphisms.
Step-by-step guide for detecting variants from DNA sequence files
This gene sheet provides details about the ACE gene and the variants examined in the TtGG laboratory protocols.
This gene sheet provides details about the ACTN gene and the variants examined in the TtGG laboratory protocols.
This gene sheet provides details about the CYP gene and the variants examined in the TtGG laboratory protocols.
This gene sheet provides details about the OXTR gene and the variants examined in the TtGG laboratory protocols.
This gene sheet provides details about the TASR gene and the variants examined in the TtGG laboratory protocols.
Our Bioinformatics lessons serve to illustrate how integral computational analyses are to the field of genomics. Bioinformatic tools help scientists understand these big data sets and drive important discoveries.
Students will "jump into bioinformatics" by exploring two databases in search of specific genetic information.
Students assess the validity of a new Alzheimer's Disease therapeutic based on a mouse model.
This case study guides students through publicly available bioinformatics databases to solve a medical mystery.
Teachers can use this guide to learn about the series of three lessons created for high school students.
Students are introduced to the Mice in Space project research goals and predict the outcomes of experiments.
Students graph real data from Mice in Space experiments and interpret the results.
A research poster template that serves as an accompaniment to Lesson 3.
Students embark on their own research project to investigate a human bone or muscle disorder.
Mighty Mice researchers published the first results from their experiments in the Proceedings of the National Academy of Sciences journal.
Students practice accurately micropipetting volumes of colored water to make a six-color rainbow from only three primary colors.
DNA Extraction begins the genotyping experiment.
PCR allows for the amplification of specific DNA sequences from a very small starting amount of DNA.
Restriction enzymes cut DNA at specific sequences, which can aid in genotyping samples.
Gel electrophoresis is the process by which fragments of DNA in a sample are separated by size.
Sequence analysis on DNA can identify single nucleotide polymorphisms.
Step-by-step guide for detecting variants from DNA sequence files
Full teacher guide with lesson descriptions, implementation strategies, NGSS alignments, and supporting materials.
Introduction to the module theme of newborn sequencing and cancer genetics.
Student activity to sort real patient data on the cBioPortal and to learn about hereditary cancer.
Student activity to uncover hereditary cancer using BLAST to perform DNA sequence comparisons.
Student activity with graphical analyses to demonstrate how environmental factors contribute to cancer risk.
Student inquiry project using cBioPortal to find and analyze data while testing a hypothesis that specific gene variants are associated with hereditary cancer.
Discussion prompts focused on the ethics of genetic testing in cancer and consent.
Students join three different research teams to learn about cancer genetics and identify treatments for melanoma.