To study tumor microenvironment and tumor immunology in cancer therapeutic resistance and metastatic relapse
The Ren group mainly focuses on elucidating how mesenchymal lineage cells (mesenchymal stem cells and fibroblasts) and immune-regulatory myeloid cells (neutrophils and macrophages) modulate the adaptive immune responses in cancer treatment resistance and metastatic relapse. These studies will fully take advantage of the unique research platform--patient-derived xenograft (PDX) tumors in humanized mouse models at The Jackson Laboratory, with the research goal to develop novel strategies targeting tumor microenvironment to improve the efficacies of conventional cancer therapies and new therapeutics such as immunotherapy.
Recipients of the 2022 Brooks Scholar Award represent a new generation of scientists whose research bridges the fields of...
This three-day intensive hands-on workshop is for those wishing to obtain practical training in vascular catheterization in the laboratory...
A stable iPSC line, KOLF2.1J, has been established to act as a high-quality baseline platform for modeling human disease.
JAX is playing a major role to bridge experimental mouse and human data and reveal the biology of senescent cells.
Trowbridge has been recognized as an outstanding early-career scientist and will receive a $750,000 award.
In this episode, we will discuss the importance of studying rare diseases and the critical preclinical steps leading to diagnosis and...
Learn about how cancer is formed in this Minute to Understanding video from The Jackson Laboratory.
To study tumor microenvironment and tumor immunology in cancer therapeutic resistance and metastatic relapse
This two-day course will help emerging scientists equip themselves with the professional, interpersonal and communication skills that...
Humans have about 20,000 genes (give or take), far fewer genes than many so-called “primitive” animals, like Daphina pulex, a.k.a. the...
Cellular senescence in the developing human placenta; discovery and validation of novel placental biomarkers to characterize placental cell...