To study tumor microenvironment and tumor immunology in cancer therapeutic resistance and metastatic relapse
The Ren group mainly focuses on elucidating how mesenchymal lineage cells (mesenchymal stem cells and fibroblasts) and immune-regulatory myeloid cells (neutrophils and macrophages) modulate the adaptive immune responses in cancer treatment resistance and metastatic relapse. These studies will fully take advantage of the unique research platform--patient-derived xenograft (PDX) tumors in humanized mouse models at The Jackson Laboratory, with the research goal to develop novel strategies targeting tumor microenvironment to improve the efficacies of conventional cancer therapies and new therapeutics such as immunotherapy.
To study tumor microenvironment and tumor immunology in cancer therapeutic resistance and metastatic relapse
Researches regulation of stem cells in the blood in normal development, aging and leukemia transformation.
Studying the mechanisms of human immunity and developing cancer immunotherapies.
Currently researching the microenvironment of breast cancer, in order to develop new strategies of immunotherapy.
JDRF has announced the launch of the JDRF Center of Excellence in New England. The new center is comprised of a team of...
Researches regulation of stem cells in the blood in normal development, aging and leukemia transformation.
Enabling the development of novel therapies for serious illnesses.
New JAX research shows that inhibiting neutrophil lipid accumulation could provide a valuable anti-metastatic therapy target for cancer...
The National Cancer Institute has awarded Jackson Laboratory cancer researcher Gary Ren a five-year grant totaling...
Dual roles of neutrophils in metastatic colonization are governed by the host NK cell status
The interaction of SARS-CoV-2, the novel coronavirus causing the global COVID-19 pandemic, and the human immune system has been the focus...
Uses genomic tools to characterize human immunity in both healthy and disease states.
The JAX Scholar award offers exceptional early-career scientists the opportunity to develop their independent research program at The...
Conducts research to understand how vaccines work and to define precisely the immune mechanisms that underlie vaccination, with a focus on...
We use cookies to personalize our website and to analyze web traffic to improve the user experience. You may decline these cookies although certain areas of the site may not function without them. Please refer to our privacy policy for more information.
Allow essential cookies
Required for basic site operations.
Allow analytics cookies
Used to analyze web traffic to improve the user experience.
Allow marketing cookies
Used to deliver personalized information and tailor communications.