Search Labs
Assessing the performance of next-generation sequencing techniques in accurate genome/epigenome/transcriptome profiling and understanding the clinical and functional role of epigenome…
Read MoreIntegrates genomic and molecular pathology approaches to investigate how the tumor microenvironment drives development and treatment resistance in brain tumors
Read MoreWe investigate how signaling programs instruct in vivo stem cells of the cochlea to differentiate into a highly specialized, organized sensory epithelium.
Read MoreSteven Munger, Ph.D., uses a systems genetics approach and advanced computational methods to study development and complex disease in advanced mouse populations.
Read MoreStudies the genetics of kidney function and disease, particularly in the context of aging.
Read MoreI lead a collaborative and interinstitutional research program that uses a multidisciplinary approach to identify early causative events underlying ‘normal’ nonpathological…
Read MoreWe are a group of geneticists, neuroscientists, and computer scientists who are passionate about discoveries of novel targets and models for mental illness through innovation at the…
Read MoreOur lab is focused on identifying and understanding the precise genetic mechanisms influencing human complex traits and risk to disease. To accomplish this our work spans several…
Read MoreResearches regulation of stem cells in the blood in normal development, aging and leukemia transformation.
Read MoreThe Beck lab uses genomics, bioinformatics and molecular biological techniques to investigate the ways in which repetitive DNA elements, such as transposons, affect human genomes.
Read MoreDevelops computational methods to study the epigenetic regulation of gene expression and its implications in important human conditions including aging and common diseases.
Read MoreInvestigates human immunological diseases and malignancy through the development and leveraging of novel humanized mouse models
Read MoreWe develop and apply innovative genome technologies to understand chromatin structure and genome function pertinent to lineage specification and disease process.
Read MoreThe application of high-resolution mass spectrometry now enables the measurement in human samples the metabolome, lipidome and small molecules of dietary, microbial and environmental…
Read MoreInvestigates the molecular mechanisms shaping hair cell architecture in the inner ear
Read MoreResearches human pancreatic islet cells and the genetic and environmental bases of type 2 diabetes.
Read MoreInvestigating the genetic mechanisms of craniofacial development and developing new genetic tools and resources for the scientific community.
Read MoreThe Adams lab develops new approaches for human and mouse microbiome analysis, seeks to understand the evolution of antibiotic resistance in Gram-negative pathogens, and contributes …
Read MoreTo study tumor microenvironment and tumor immunology in cancer therapeutic resistance and metastatic relapse
Read MoreThe overall focus of my research program has been to understand the molecular and cellular mechanisms underlying tissue growth and tissue regeneration with the long-term goal of…
Read MoreThe Oh Lab studies the human microbiome for its potential to deliver treatments for infectious and other diseases. (Image by Alex Valm, NHGRI)
Read MoreStudying the mechanisms of human immunity and developing cancer immunotherapies.
Read MoreCaptures gene expression data and disseminates it to the research community.
Read MoreDevelops algorithms and software for the analysis of exome and genome sequences.
Read MoreThe Robson lab utilizes advanced molecular, cellular, and stem cell biology approaches to study evolution, development, and disease relevant to the human condition.
Read MoreInvestigating the mechanisms of autoimmune disease to devise therapeutic approaches.
Read MoreGlobal leader in the use of targeted mutagenesis in mice to investigate muscle development, disease and repair.
Read MoreInvestigates how alternative RNA splicing contributes to cancer with the goal of identifying novel clinical biomarkers and targets for precision medicine.
Read MoreStudies synapse development and function relevant to human neuromuscular disorders.
Read MoreDeveloping new computational strategies to understand complex genetic systems.
Read MoreResearches the genetics underlying behavior and identifies relationships among behavioral traits.
Read MoreInvestigating the genetics of health and disease with a systems approach.
Read MoreResearching the mechanisms that generate genetic diversity through the lens of evolution
Read MoreInvestigates the genetic regulation of meiosis and the mechanisms of male fertility to understand how errors in meiosis can lead to developmental abnormalities.
Read MoreResearching meiosis, the mechanisms of DNA damage detection and repair during normal development of gametes, and implications for fertility of cancer patients after radiation …
Read MoreBridging the digital biology divide, integrating computation with biomedical research.
Read MoreEmploys mouse models of human eye disease to study gene function and mechanisms underlying disease pathology.
Read MoreThe overarching goal of my NIH-funded research program is to understand the neural control of appetite and how diet and body weight affect the excitability of the neurons in key …
Read MoreHuman pluripotent stem cells and the human embryo: Human pluripotent stem cells (hPSC) have opened up a previously inaccessible phase of the human life cycle to experimental study.
Read MoreResearches blood formation with a focus on red blood cells and the genetics underlying defects leading to anemias.
Read MoreDr. Reinholdt’s research focuses on comparative and functional mammalian genomics, reproductive development and stem cell biology.
Read MoreThe Bloss Lab leverages high resolution imaging, observation and manipulation of in vivo neural activity, and genetic perturbations in specific neurons to define how neural circuits…
Read MoreResearches the genetics of aging and lifespan, seeking to understand the basic mechanisms of aging, and adult stem cells, with the goal of delaying normal aging processes.
Read MoreThe Lee Lab studies structural genomic variation in human biology, evolution and disease.
Read MoreUsing genomic technologies and mouse modeling including patient-derived xenografts (PDX) and genetically engineered mouse models (GEMM), we are discovering and validating novel…
Read MoreUtilizing genomic approaches to interrogate mechanisms of inherited cardiovascular disorders.
Read MoreThe Wang Laboratory at The Jackson Laboratory for Genomic Medicine is interested in understanding gene regulatory mechanisms that regulate leukemia survival, differentiation and…
Read MoreLeadership
Ph.D., FMedSci, FAAHMS
Scientific Director and Professor, The Jackson Laboratory for Mammalian Genetics, the Maxine Groffsky Endowed Chair
Meet NadiaPh.D., FACMG
Scientific Director and Professor, The Jackson laboratory for Genomic Medicine, Robert Alvine Family Endowed Chair
Meet CharlesPh.D.
Interim Vice President of Research, Professor and Director of Protein Sciences
Meet AndyVoices of JAX
“I was attracted by how diverse the research programs are at JAX, beyond just cancer. I think it’s great to benefit from researchers with diverse expertise and backgrounds.”
– Assistant Professor Eric Wang, Ph.D., leukemia researcher
Latest News
The Jackson Laboratory is working on multiple efforts related to endometriosis, including research to discovery causes and therapy targets, to increase…
Read MorePaul Flicek, D.Sc., joins JAX as its inaugural chief data science officer to build a global data science initiative.
Read MoreDerya Unutmaz and Julia Oh are helping to remove the obstacles for diagnosing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).
Read More