Neurons are the specialized cells in our nervous system that generate and transmit information. Our thoughts and actions depend on proper neuron function, from within our brains to the junctions that control muscle contraction. Disorders that cause neuron degeneration, dysfunction and death can be devastating, and for many—Alzheimer’s disease, Parkinson’s disease, ALS, muscular dystrophy—there is no cure.
We research neuronal development and function, and the mechanisms of degeneration and disease. Understanding the inner workings of our most complex and vital system is essential to finding what goes wrong in disease. And it will help provide the insight necessary to develop early detection screens and effective disease interventions.