Rare Diseases

Rare and orphan diseases affect fewer than 200,000 individuals in the United States, and nearly 700,000 rare diseases have been described to date. The Jackson Laboratory offers the world's largest collection of spontaneous, targeted, and transgenic mutant mouse strains, hundreds of which model rare diseases. 

Rare and Orphan Disease Mouse Models

Search for mouse models by human disease term.

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Research Tools and Online Resources

Discover helpful tools for advancing your rare and orphan disease research.

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Rare and Orphan Disease Center

The Rare and Orphan Disease Center brings together global mouse resources and the expertise of scientists at the Jackson Laboratory for a start-to-finish approach to model development.

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