Rare and Orphan Disease Mouse Models
Search for mouse models by human disease term.
Rare and orphan diseases affect fewer than 200,000 individuals in the United States, and nearly 700,000 rare diseases have been described to date. The Jackson Laboratory offers the world's largest collection of spontaneous, targeted, and transgenic mutant mouse strains, hundreds of which model rare diseases.
JAX has teamed with Lovelace Biomedical, Exemplar Genetics, Iontox and the University of Pennsylvania to win a new $17M contract with the...
Two new mouse models created to study neurological developments in Snyder-Robinson Syndrome to advance global understanding of this rare...
Rare and Orphan Disease Research Tools and Online Resources
Did you know that almost all of us have the sort of genetic mutations that cause rare genetic diseases?
Families have banded together from across the globe to make awareness and research for SMARD a reality.
Efficacy studies are performed by JAX on mouse models for these diseases: C57BL10.mdx and D2.mdx for DMD, DyW for CMD1A, and A/J for...
A team from The Jackson Laboratory attended a Rare Disease Day 2016 event in Maine to help educate state legislators and staff about the...
Genetic diversity should be accounted for in pre-clinical tests, and researchers need to select the right model system to mimic human...
JAX distributes well-characterized, preclinical mouse models to accelerate drug discovery for rare and orphan diseases.
We engineer new models and enhance existing models through genetic standardization and characterization to ensure reproducibility of data...
We partner with foundations, pharmaceutical and biotech companies, and other scientists to research treatments for uncommon...
This new video from The Cox Lab video offers an inside look at the research goals of Amy Hicks, a postdoctoral associate who is studying...
JAX Professor Robert Burgess and collaborators are developing personalized gene therapy for a Texas child suffering from a neuromuscular...
New research provides an intriguing therapy target for some forms of Charcot-Marie-Tooth disease type 2.
Cortney Lavorgna is a college student who is exploring the neuromuscular disease she lives with in a JAX research...
Over 30,000 peer-reviewed publications cite use of JAX® Mice strains. Hundreds of new papers referencing JAX® Mice strains are published...