The Robinson Lab
Develops algorithms and software for the analysis of exome and genome sequences.
Principal Investigator
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The Robinson Lab is primarily located at The Jackson Laboratory. Together with the Phenomics Team, our group develops the Human Phenotype Ontology and applications of this ontology to differential diagnostics and genomics analyses.
We develop algorithms for exome and genome sequencing, ChIP-seq, immunogenomics, and other genomics applications, Gene Ontology analysis, computational phenotype analysis, as well as various algorithms from the fields of Machine Learning and modeling of biological networks with the tools of linear algebra and graph theory. We also collaborate on the computational analysis of wetlab biological data, especially in the fields of human hereditary disease and the molecular basis of bone development and fracture healing.
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Press ReleaseJune 08, 2023Historic endometriosis bill approved by Connecticut legislature
The first-of-its-kind program supports endometriosis patients. -
Research HighlightMay 31, 2023Variation in Diversity Outbred mice epigenetics
New research finds that the epigenetic landscape is highly variable between the strains of Diversity Outbred mice and is associated with variation in gene expression. -
Blog PostMay 04, 2023JAX Genomic Education leads DNA Day 2023 celebrations
JAX Genomic Education joined the global celebration of all things genetics across JAX campuses, online, and in our communities. -
Research HighlightApril 11, 2023Churchill Lab performs multi-omics study on protein phosphorylation regulators
The Churchill lab performed an integrative multi-omics analysis of 58 genetically diverse Collaborative Cross strains to identify regulators of protein phosphorylation.
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Research HighlightJune 01, 2023New phenopacket-tools released to simplify construction of phenopackets
Peter Robinson and colleagues have developed phenopacket-tools, which simplify construction of phenopackets by providing programmatic shortcuts and predefined building blocks. -
Research HighlightMay 09, 2023Variability in the earliest stages of development
The processes enabling pluripotency at the very beginning of life are more different between mouse strains than you might expect. -
Research HighlightApril 27, 2023Uncovering the genetic secrets behind human uniqueness
Ryan Tewhey is part of a research group that identified and characterized more than 10,000 human-specific Conserved Deletions (hCONDELs) enriched for brain functions. The findings will be important for further investigation of the evolutionary mechanisms that produce the traits that distinguish humans from other species. -
Research HighlightApril 05, 2023Exploring genetic diversity in mouse strains
Christine Beck led a team that explored mouse genome, and revealed details across 20 diverse inbred strains that will be critical for informing mouse-based genetics and genomics research moving forward.