Jackson Laboratory

Computational Biology

Our Research Focus

When we think of biology research, we usually think of traditional “wet” labs where experiments are performed and data are generated. But much of our research these days is computational, done in what are known as “dry” labs. Today’s data sets are of such magnitude and complexity that advanced computational methods are essential for data analysis, management and dissemination.

Our computational biology work investigates the precise makeup of both mouse and human genomes and the similarities (and important differences) important for translating preclinical research to clinical benefit. We are also analyzing whole-genome structure, identifying gene networks and understanding gene expression and its regulation, constructing computational models from genomic data so that function and dysfunction can be predicted based on established patterns, and more.

Faculty & Staff

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Postdoctoral Associate

Tamar Abel, Ph.D.

Assistant Professor, Lab Staff, Principal Investigator

Rafiou Agoro, Ph.D.

Joseph Albert, B.S.

Computational Scientist

Elaheh Alizadeh, Ph.D.

Kevin J. Anderson, Ph.D.

Bri Angello, B.S.

Alumni

Sam Ardery

Lab Staff

Peter Audano, III, Ph.D.

Lab Staff

Selcan Aydin, Ph.D.

Lab Staff

Parithi Balachandran, MS

Assistant Professor

Christine Beck, Ph.D.

Lab Staff

Isaac Bell

Lab Staff

Daniel Berenzy

Software Engineer

Alexander Berger, B.S.

Lab Staff

Redwan M Bhuiyan, BA

Lab Staff

Laura Blanco-Berdugo, MS

John Bluis, M.S.,B.S.

Research Scientist

Molly Bogue, Ph.D.

Lab Staff

Samantha Bossé

Professor

Carol Bult, Ph.D.

Professor

Gregory Carter, Ph.D.

Software Engineer

Francisco Castellanos, M.S.

Bioinformatics/Data Analyst

Harshpreet Chandok, M.S.

Computational Scientist

Damien Chaussabel, Ph.D.

Alumni

Yang Chen, Ph.D.

Professor

Elissa J. Chesler, Ph.D.

Lab Staff

Jaycee Choi

Lab Staff

Anshul Choudhary, Ph.D.

Professor

Jeffrey Chuang, Ph.D.

Professor

Gary Churchill, Ph.D.

Lab Staff

Ben Coleman

Computational Scientist

Daniel Danis, Ph.D.

Postdoctoral Associate

Georgia Doing, Ph.D.

Sergii Domanskyi, Ph.D.

Associate Professor

Beth Dumont, Ph.D.

Alumni, Software Engineer

Matthew Dunn, B.S.

Baha El Kassaby, MSc

Computational Scientist, Software Engineer

Jake Emerson, M.S.

Lab Staff, Predoc

Ardian Ferraj, Ph.D.

Computational Scientist

Peter Fields, Ph.D.

Alumni

Alexander Fine

Lab Staff

Bill Flynn, Ph.D.

Ali Forougi Pour, Ph.D.

Bioinformatics/Data Analyst

Zachary Frohock

Associate Research Scientist

Mayuko Furuta, Ph.D.

Software Engineer

Michael Gargano, B.S.

Predoc

Alexis Garretson, MS

Daniel Gatti, Ph.D.

Lab Staff

Eva Gega, M.S.

Joshy George, Ph.D.

Lab Staff

Orianna Goldberg

Postdoctoral Associate

Minghao Gong, Ph.D.

Lab Staff

Titas Grabauskas

Lab Staff

Annat Haber, Ph.D.

Associate Research Scientist

Pille Hallast, Ph.D.

Computational Scientist

Jeffrey Harder, Ph.D.

Hao He, Ph.D.

Alumni

Leinani Hession

Research Scientist, Scientific Curator

David Hill, Ph.D.

Research Scientist

Kevin C. Johnson, Ph.D.

Beena Kadakkuzha, Ph.D.

Lab Staff

Stephen Keegan

Computational Scientist

Taushif Khan, Ph.D.

Postdoctoral Associate

Kwondo Kim, Ph.D.

Alumni

Ji Hun Kim, Ph.D.

Neil Kindlon, M.S.

Computational Scientist

Mitch Kostich

Associate Professor

Vivek Kumar, Ph.D.

Predoc

Sonal Kumar

Predoc

Peter Larson, BS

Raman Akinyanju Lawal, Ph.D.

Alumni

Donghyung Lee, Ph.D.

Lab Staff

Sai Lek

Associate Professor

Shuzhao Li, Ph.D.

Associate Professor

Sheng Li, Ph.D.

Yi Li, Ph.D.

Computational Scientist

Hongping Liang, Ph.D.

Associate Research Scientist

Yang Liu, Ph.D.

Computational Scientist

Michael Lloyd, Ph.D.

Matt Mahoney, Ph.D.

Associate Research Scientist

Radu Marches, Ph.D.

Alumni

Eladio Marquez, Ph.D.

Seamus Mawe, B.A.

Dave Mellert, Ph.D.`

Postdoctoral Associate

Adrian Melo Carrillo, Ph.D.

Associate Research Scientist

Francesca Menghi, Ph.D.

Lab Staff

Nicholas Moskwa, Ph.D.

Efthymios Motakis, Ph.D.

Associate Professor

Steven Munger, Ph.D.

Postdoctoral Associate

Lamis Naddaf, Ph.D.

Professor

Jürgen Naggert, Ph.D.

Associate Research Scientist

Djamel Nehar-Belaid, Ph.D.

Postdoctoral Associate

Francis O'Neill, M.D., M.A.

Predoc

Hilda Opoku Frempong

Bioinformatics/Data Analyst

Carolyn Paisie, Ph.D.

Predoc

Ziwei Pan

Lab Staff

Ravi Pandey, Ph.D.

Software Engineer

Jim Peterson, M.S.

Director

Vivek Philip, Ph.D.

Lab Staff

Avijit Podder, Ph.D.

Olivier Bertrand Poirion, Ph.D.

Alumni

Narayanan Raghupathy, Ph. D.

Postdoctoral Associate

Sathyabaarathi Ravichandran, Ph.D.

Gabriel E. Rech, Ph.D.

Lab Staff, Senior Research Scientist

Joel Richardson, Ph.D.

Professor

Peter Robinson, M.D., MSc.

Alumni

Wojciech Rosikiewicz, Ph.D.

Research Scientist

Jill Rubinstein, MD, Ph.D.

Shane Sanders, Ph.D.

Computational Scientist

Michael Saul, Ph.D.

Software Engineer

Nick Sebasco, MS

Research Scientist

Martine Seignon

Lab Staff

Susan Sheehan, BA, MS

Research Scientist

Santhosh Sivajothi, Ph.D.

Research Scientist

Daniel Skelly, Ph.D.

Research Scientist

Cynthia Smith, Ph.D.

Lab Staff

Catrina Spruce, MS, BS

Bioinformatics/Data Analyst

Grace Stafford, Ph.D.

Biostatistician

Timothy M. Stearns, B.S., M.S.

Associate Professor

Michael Stitzel, Ph.D.

Software Engineer

Beth Sundberg, M.S.

Postdoctoral Associate

Aaron Taylor, Ph.D.

Associate Professor

Ryan Tewhey, Ph.D.

Postdoctoral Associate

Abdulfatai Tijjani, DVM, Ph.D.

Lab Staff

Harianto Tjong, Ph.D.

Mohammed Toufiq

Jarek Trapszo

Computational Scientist

Rohit Tripathy

Associate Research Scientist

Anna Tyler, Ph.D.

Associate Professor

Duygu Ucar, Ph.D.

Lab Staff

Robert Valenzuela

Assistant Professor

Frederick Varn, Ph.D.

Software Engineer

Dave Walton, B.A.

Computational Scientist

Benjamin Walton, B.S.

Research Scientist

Julie Wells, Ph.D.

Postdoctoral Associate

Ann Wells, Ph.D.

Brian White, Ph.D.

Computational Scientist

Sam Widmayer, Ph.D.

Lydia Wooldridge, Ph.D.

Lab Staff

Ruoyu Yang, B.S.

Associate Research Scientist

Chun Yu, Ph.D.

Computational Scientist

Miao Yu, Ph.D.

Lab Staff

Marina Yurieva, Ph.D.

Alumni

Y. Ada Zhan, Ph.D.

Ji-Gang Zhang, Ph.D.

Associate Research Scientist

Lihong Zhao, Ph.D.

Alumni

Zi-Ming Zhao, Ph.D.

Computational Scientist

Yue Zhao

Computational Scientist

Wei Zhou, Ph.D.

Wulin Zuo, Ph.D.

Research Centers & Resources

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Research HighlightApril 23, 2024
Investigating age-related immune dysfunction in lung epithelial cells
With $13 million in renewed support, Karolina Palucka will further study how aging affects airway epithelial cells’ efficiency in combating viral infections.
Featured ArticleApril 23, 2024
Dan Cortes: gearing up for discovery
Dan Cortes multifaceted journey has led him to pioneering stem cell research within the Pera lab, where he explores the intricate genetic landscape underlying neurological diseases and disorders.
Featured ArticleMarch 26, 2024
Working to characterize the function of protein-coding genes in the mouse
Using KOMP2, JAX researchers have now generated and characterized more than 2,000 knockout mice, gaining important insights into mammalian genetics and potential health impacts.
- Model Development
- Genetics and Genomics
Featured ArticleMarch 14, 2024
2024 Paigen Fellowship recognizes postdoctoral talent
The Paigen Fellowship supports postdoctoral associate Abdulfatai Tijjani's humanistic approach to research.

Featured ArticleApril 23, 2024
Charles Lee receives honorary doctor of science degree from University of Alberta
Charles Lee awarded honorary doctor of science degree from the University of Alberta and will deliver the convocation address to Faculty of Science graduates.
Research HighlightApril 03, 2024
Making mice a more powerful research tool
A new protocol sets the stage for researchers to directly compare mouse and human cells, and readily incorporates genetic diversity into mouse-based research to more closely approximate human health conditions.
Press ReleaseMarch 21, 2024
Aubrey Watkins III appointed VP of Corporate Development
Industry leader and innovator will help advance JAX’s mission.
- Meet our donors
- Genetics and Genomics
Featured ArticleMarch 12, 2024
2024 JAX Scholars announced
JAX is proud to announce Takeshi Iwasaki, M.D., Ph.D., and Morgan Severn, Ph.D., as the 2024 JAX Scholars.
- Microbiome
- Genetics and Genomics

Upcoming Education

May 13 - 16

Workshop

Long-Read Sequencing Workshop

Precision medicine, Genetics and Genomics, Bioinformatics, Computational Biology

May 17 - 23

Workshop

Workshop on Techniques in Modeling Human Cancer in Mice

Endocrinology, Genetic Tools, Rare Diseases, Neurodegenerative Disease, Cancer/Tumors, Genetics and Genomics, Cancer

May 29 - 30

Short Course

The Whole Scientist Regional Short Course

Aging, Behavioral Disorders, Bioinformatics, Cancer, Computational Biology, Complex Traits, Developmental Disorders, Diabetes and Obesity, Eye Research, Genetics and Genomics, Immune Disorders, Skin Disease, Infectious Disease Research, Neurodegenerative and Neuromuscular Diseases, Reproductive Disorders, Resource Development and Dissemination

Jun10

Hybrid Event

Precision medicine, Ethics, Stem cells, Microbiome, Infectious Disease, Immunology, Model Development, Rare Diseases, Aging, Cardiovascular, Cancer/Tumors, Developmental Biology, Diabetes, Genetic Tools, Optogenetics and Pharmacogenetics, Autoimmunity, Inflammation, Lupus, Addiction, Dermatology, Autoimmune Diseases Information, Metabolic Diseases, Neurodegenerative Disease, Reproductive Biology, Down Syndrome, Fragile X, Rett Syndrome, Neurodevelopmental Defects, Metabolic Defects, Cystic Fibrosis, Genetics and Genomics, Reproductive Disorders, Complex Traits, Developmental Disorders, Diabetes and Obesity, Neurodegenerative and Neuromuscular Diseases, Immune Disorders, Bioinformatics, Computational Biology, Cancer

Online Courses and On-Demand Webinars

Online Courses