Christine Beck, Ph.D.

Assistant Professor

Investigating the mechanisms and consequences of genomic rearrangements with a focus on repetitive elements.

Visit The Beck Lab

Location

Farmington, CT

Contact

207-288-6000

Connect

More by @christinerbeck

Recent Tweets

  • Christine R. Beck
    @RosenbergLabBCM @oberlincollege I'm so sorry you and Phil are going through this and have to deal with media on top of everything. My thoughts are with both of you.
  • Christine R. Beck
    Happy to be a part of a great team of scientists working on communicating ASHG-related programming! t.co/rWenIhA1yJ
  • Christine R. Beck
    RT @peteraudano: I am presenting today at #ASHG21 (10:45 ET). PAV: Long-read variant detection including SVs, small variants, and cryptic i…
  • Christine R. Beck
    #ASHG2021 is in full swing! The Beck lab has a talk and some great posters, including a poster talk! Stop by, and ask us questions! "See" you around at all of the great scientific presentations all week long.

The mechanisms governing non-recurrent human structural variation (SV) are diverse and often poorly understood. I am investigating how human DNA maintains fidelity in the context of a repetitive genome. For example, human Alu elements number over one million copies per human genome, and recent studies have found that these repeat sequences often mediate SVs in some loci. Through computational, molecular biological and genomic techniques, we will identify regions susceptible to this form of SV and investigate the enzymes that limit or promote Alu-mediated rearrangements. These lines of inquiry could find regions prone to instability in human cancers and lead to targets for therapy.

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Christine Beck on ORCID