Christine Beck, Ph.D.

Assistant Professor

Investigating the mechanisms and consequences of genomic rearrangements with a focus on repetitive elements.

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Farmington, CT


More by @christinerbeck

Recent Tweets

  • Christine R. Beck
    RT @todd_macfarlan: I am looking for a staff scientist to join my group at the NIH in Bethesda, Maryland. Competitive salary and benefits,…
  • Christine R. Beck
    @sebatlab Right after you bring in more cookies, right? I mean, you know what's best for lab productivity, and it's carbs and mentorship, right? Am I doing this all wrong?

The mechanisms governing non-recurrent human structural variation (SV) are diverse and often poorly understood. I am investigating how human DNA maintains fidelity in the context of a repetitive genome. For example, human Alu elements number over one million copies per human genome, and recent studies have found that these repeat sequences often mediate SVs in some loci. Through computational, molecular biological and genomic techniques, we will identify regions susceptible to this form of SV and investigate the enzymes that limit or promote Alu-mediated rearrangements. These lines of inquiry could find regions prone to instability in human cancers and lead to targets for therapy.

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Christine Beck on ORCID