The Bolcun-Filas Lab
Researching the mechanisms of DNA damage detection and repair and their implications for cancer patients.
Researching the mechanisms of DNA damage detection and repair and their implications for cancer patients.
Press Release
May 17, 2016
Female cancer patients may be able to retain their fertility during radiation and chemotherapy through treatments that target the DNA damage response in oocytes.
Profile Story
August 21, 2015
Profile of Ewelina Bolcun-Filas, whose research aims to understand the molecular mechanisms controlling the development of healthy gametes and how misregulation of these mechanisms can lead to reproductive disorders.
The Search Magazine Article
October 01, 2012
The Jackson Laboratory's research program into the earliest stages of life has a proud history and a bright future.
This brief article reviews the technique and considerations for superovulating female mice.
Research Highlight
June 09, 2017
JAX researcher Ewelina Bolcun-Filas, Ph.D., contributed to a study that could advance development of drugs to prevent infertility caused by cancer-treating radiation.
The Search Magazine Article
December 01, 2015
Targeted therapies will yield huge gains, with fewer severe side effects, compared to the sledgehammer chemotherapeutic and radiation approaches—which kill all quickly dividing cells—currently serving as the standard of care.
The Search Magazine Article
August 26, 2015
Ewelina Bolcun-Filas, Ph.D., is researching how to protect female fertility despite radiation-induced DNA damage, so female cancer patients retain the option of having children later in life.
Review these guidelines for determining the estrus state of female mice and setting up timed pregnancies.