Down Syndrome

Down syndromeis a genetic disorder caused by the presence of an extra chromosome.

A rare disease calls for a unique mouse model

Personal Story November 18, 2016 Learn More

Drug normalizes learning in Down syndrome mice

eNews July 01, 2010 Learn More

News and Insights

Personal StoryNovember 18, 2016

A rare disease calls for a unique mouse model

eNewsJuly 01, 2010

Drug normalizes learning in Down syndrome mice

JAX NotesApril 06, 2010

Down syndrome is caused partly by gene under-expression, not just over-expression

eNewsSeptember 01, 2009

Genetic Linkage between Down syndrome and reduced cancer incidence revealed

Education Resources

Jul Aug 22 - 02
Short Course

Human and Mammalian Genetics and Genomics: The 65th McKusick Short Course

Precision medicine, Ethics, Stem cells, Microbiome, Infectious Disease, Immunology, Model Development, Rare Diseases, Aging, Cardiovascular, Cancer/Tumors, Developmental Biology, Diabetes, Genetic Tools, Optogenetics and Pharmacogenetics, Autoimmunity, Inflammation, Lupus, Addiction, Dermatology, Autoimmune Diseases Information, Metabolic Diseases, Neurodegenerative Disease, Reproductive Biology, Down Syndrome, Fragile X, Rett Syndrome, Breast Cancer, Neurodevelopmental Defects, Metabolic Defects, Cystic Fibrosis, Genetics and Genomics, Reproductive Disorders, Complex Traits, Developmental Disorders, Diabetes and Obesity, Neurodegenerative and Neuromuscular Diseases, Immune Disorders, Bioinformatics, Computational Biology, Cancer

Research & Faculty

Cytogenetic and Down Syndrome Models Resource

The Jackson Laboratory maintains and distributes chromosome-aberration stocks that provide mouse models for Down syndrome, as well as the study of chromosomal aneuploidy.