The purpose of my research at the Ching Lau Lab is to examine genomic and epigenomic data from pediatric cancers in order to discover molecular phenotypes, prognostic biomarkers and candidate therapeutic targets. My work includes method and pipeline development for integration of multi-omic data in the analysis of pediatric brain, bone and blood tumors to develop a better molecular understanding of these often-lethal cancers, and to develop diagnostic classifiers utilizing liquid biopsies. Currently, my research focuses on osteosarcoma, myeloid leukemia of Down syndrome (ML-DS), and intracranial germ cell tumors.
