Stem cells may hold the key to breakthroughs in many of the Laboratory’s research areas, with particular emphasis focused on their role in cancer and aging.
The Cheng lab develops technologies based on artificial DNA and RNA binding proteins and applies them to sense or induce sequence or epigenetic changes at target genomic loci or target transcripts.
International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.
Scientific Director and Professor, The Jackson Laboratory for Mammalian Genetics
Human pluripotent stem cells and the human embryo: Human pluripotent stem cells (hPSC) have opened up a previously inaccessible phase of the human life cycle to experimental study.
Global leader in the use of targeted mutagenesis in mice to investigate muscle development, disease and repair.