Jackson Laboratory

Immunology Inflammation and Rheumatology

The Jackson Laboratory is at the forefront of the new thinking about how the body’s immune response and inflammation contribute to a variety of diseases, including cancer and diabetes.

News and Insights

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Research HighlightFebruary 01, 2021

Novel antibody tests reveal complexity of immune response to covid-19

Blog Post January 20, 2021

Advancing Humanized NSGTM Mice for Immuno-Oncology Testing

Blog Post April 21, 2020

CD34+ Hematopoietic Stem Cell Humanized Mice: The Basics

Press ReleaseJanuary 23, 2020

Small molecules mean big data for health and disease

eNewsOctober 29, 2019

Leveraging our immune systems for good

Press ReleaseAugust 01, 2019

Preventing anaphylaxis

Search MagazineApril 11, 2019

Tipping the balance in the fight against cancer

Blog Post March 27, 2019

Revealing antibody half-life and stability using FcRn mouse models from JAX

Immunology

Related Services

Imiquimod-Induced Psoriasis Efficacy Studies

Immunology Services

Most popular JAX Mice strains

Genome Scanning Service

Breeding Services

Education Resources

Nov30

Webinar Series

Humanized Mice Journal Club

Jul 18 - 28

Short Course

Human and Mammalian Genetics and Genomics: The 63rd McKusick Short Course

Precision medicine, Ethics, Stem cells, Microbiome, Infectious Disease, Immunology, Model Development, Rare Diseases, Aging, Cardiovascular, Cancer/Tumors, Developmental Biology, Diabetes, Genetic Tools, Optogenetics and Pharmacogenetics, Autoimmunity, Inflammation, Lupus, Addiction, Dermatology, Autoimmune Diseases Information, Metabolic Diseases, Neurodegenerative Disease, Reproductive Biology, Down Syndrome, Fragile X, Rett Syndrome, Breast Cancer, Neurodevelopmental Defects, Metabolic Defects, Cystic Fibrosis, Genetics and Genomics, Reproductive Disorders, Complex Traits, Developmental Disorders, Diabetes and Obesity, Neurodegenerative and Neuromuscular Diseases, Immune Disorders, Bioinformatics, Computational Biology, Cancer

Jul 18 - 28

Virtual Event or Webinar

Virtual Event - Human and Mammalian Genetics and Genomics: The 63rd McKusick Short Course

Precision medicine, Ethics, Stem cells, Microbiome, Infectious Disease, Immunology, Model Development, Rare Diseases, Aging, Cardiovascular, Cancer/Tumors, Developmental Biology, Diabetes, Genetic Tools, Optogenetics and Pharmacogenetics, Autoimmunity, Inflammation, Lupus, Addiction, Dermatology, Autoimmune Diseases Information, Metabolic Diseases, Neurodegenerative Disease, Reproductive Biology, Down Syndrome, Fragile X, Rett Syndrome, Breast Cancer, Neurodevelopmental Defects, Metabolic Defects, Cystic Fibrosis, Genetics and Genomics, Reproductive Disorders, Complex Traits, Developmental Disorders, Diabetes and Obesity, Neurodegenerative and Neuromuscular Diseases, Immune Disorders, Bioinformatics, Computational Biology, Cancer

Aug 15 - 26

Virtual Event or Webinar

Virtual Event - 31st Annual Short Course on Experimental Models of Human Cancer

Aug 15 - 26

Short Course

31st Annual Short Course on Experimental Models of Human Cancer

Sep Oct 24 - 01

Workshop

20th Annual Workshop on the Pathology of Mouse Models for Human Disease

Model Development, Stem cells, Aging, Autoimmune Diseases Information, Bones and Joints, Dermatology, Cancer/Tumors, Digestion, Resource Development and Dissemination, Aging

Research & Faculty

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Biology of Beta Cell Consortium

NOD-scid IL2rgnull (NSG) and NOD-Rag1null IL2rgnull (NRG) mice support heightened levels of engraftment with human cells and tissues. These engrafted mice allow research on human disease processes without putting individuals at risk.

The Cheng Lab

The Cheng lab develops technologies based on artificial DNA and RNA binding proteins and applies them to sense or induce sequence or epigenetic changes at target genomic loci or target transcripts.

Chun Yu, Ph.D.

Associate Research Scientist

Guangwen "Gary" Ren, Ph.D.

Guangwen "Gary" Ren, Ph.D.

Assistant Professor

The Howell Lab

Investigates the early stages of age-related neurodegenerative diseases.

Immune Disorders

Researching the basic biology of the immune response, autoimmunity, the role of the immune system in glaucoma, cancer and other diseases, and more.

Jeffrey Harder, Ph.D.

Jeffrey Harder, Ph.D.

Postdoctoral Fellow

Michael Stitzel, Ph.D.

Associate Professor

Mouse Genome Informatics

International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.

Mouse Mutant Resource

Mice harboring spontaneous mutations have long been a major source for animal models of human genetic disorders, particularly mendelian diseases. The Mouse Mutant Resource maintains over 700 established mutant strains.

The Ringwald Lab

Captures gene expression data and disseminates it to the research community.

The Shultz Lab

Investigates human immunological diseases and malignancy through the development and leveraging of novel humanized mouse models

The Stitzel Lab

Researches human pancreatic islet cells and the genetic and environmental bases of type 2 diabetes.

The Ucar Lab

Develops computational methods to study the epigenetic regulation of gene expression and its implications in important human conditions including aging and common diseases.