Immunology Inflammation and Rheumatology

The Jackson Laboratory is at the forefront of the new thinking about how the body’s immune response and inflammation contribute to a variety of diseases, including cancer and diabetes.

CD34+ Hematopoietic Stem Cell Humanized Mice: The Basics

Blog Post April 21, 2020 Learn More

Small molecules big data for health and disease

Press Release January 23, 2020 Learn More

News and Insights

Blog Post April 21, 2020

CD34+ Hematopoietic Stem Cell Humanized Mice: The Basics

Press ReleaseJanuary 23, 2020

Small molecules big data for health and disease

eNewsOctober 29, 2019

Leveraging our immune systems for good

Press ReleaseAugust 01, 2019

Preventing anaphylaxis

Search MagazineApril 11, 2019

Tipping the balance in the fight against cancer

Blog Post March 27, 2019

Revealing antibody half-life and stability using FcRn mouse models from JAX

Press ReleaseMarch 05, 2019

JAX receives grant to learn why flu vaccines are less effective in the elderly

Blog Post February 17, 2019

Investigating immunomodulation: Examining GvHD using Humanized NSG™ mice from JAX

Related Services

Imiquimod-Induced Psoriasis Efficacy Studies

Sponsored Strain Distribution

Immunology Services

Most popular JAX Mice strains

Genome Scanning Service

Breeding Services

Education Resources

Aug 17 - 28
Virtual Event or Webinar

29th Annual Short Course on Experimental Models of Human Cancer (Virtual Event)

Oct 04 - 10
Workshop

19th Annual Workshop on the Pathology of Mouse Models for Human Disease - Canceled

Model Development, Stem cells, Aging, Autoimmune Diseases, Bones and Joints, Dermatology, Cancer/Tumors, Digestion, Resource Development and Dissemination, Aging
Jul 19 - 30
Short Course

Human and Mammalian Genetics and Genomics: The 62nd McKusick Short Course

Precision medicine, Ethics, Stem cells, Microbiome, Infectious Disease, Immunology, Model Development, Rare Diseases, Aging, Cardiovascular, Cancer/Tumors, Developmental Biology, Diabetes, Genetic Tools, Optogenetics and Pharmacogenetics, Autoimmunity, Inflammation, Lupus, Addiction, Dermatology, Autoimmune Diseases, Metabolic Diseases, Neurodegenerative Disease, Reproductive Biology, Down Syndrome, Fragile X, Rett Syndrome, Breast Cancer, Neurodevelopmental Defects, Metabolic Defects, Cystic Fibrosis, Genetics and Genomics, Reproductive Disorders, Complex Traits, Developmental Disorders, Diabetes and Obesity, Neurodegenerative and Neuromuscular Diseases, Immune Disorders, Bioinformatics, Computational Biology, Cancer
Aug 19 - 28
Short Course

30th Annual Short Course on Experimental Models of Human Cancer

Research & Faculty

Biology of Beta Cell Consortium

NOD-scid IL2rgnull (NSG) and NOD-Rag1null IL2rgnull (NRG) mice support heightened levels of engraftment with human cells and tissues. These engrafted mice allow research on human disease processes without putting individuals at risk.

The Cheng Lab

The Cheng lab develops technologies based on artificial DNA and RNA binding proteins and applies them to sense or induce sequence or epigenetic changes at target genomic loci or target transcripts.

Chun Yu, Ph.D.

Associate Research Scientist

Guangwen "Gary" Ren, Ph.D.

Assistant Professor

The Howell Lab

Investigates the early stages of age-related neurodegenerative diseases.

Immune Disorders

Researching the basic biology of the immune response, autoimmunity, the role of the immune system in glaucoma, cancer and other diseases, and more.

Jeffrey Harder, Ph.D.

Postdoctoral Fellow

Michael Stitzel, Ph.D.

Associate Professor

Mouse Genome Informatics

International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.

Mouse Mutant Resource

Mice harboring spontaneous mutations have long been a major source for animal models of human genetic disorders, particularly mendelian diseases. The Mouse Mutant Resource maintains over 700 established mutant strains.

The Ringwald Lab

Captures gene expression data and disseminates it to the research community.

The Shultz Lab

Investigates human immunological diseases and malignancy through the development and leveraging of novel humanized mouse models

The Stitzel Lab

Researches human pancreatic islet cells and the genetic and environmental bases of type 2 diabetes.

The Ucar Lab

Develops computational methods to study the epigenetic regulation of gene expression and its implications in important human conditions including aging and common diseases.