Immunology Inflammation and Rheumatology

The Jackson Laboratory is at the forefront of the new thinking about how the body’s immune response and inflammation contribute to a variety of diseases, including cancer and diabetes.

Systemic Immune Responses - Humanized Mice

Blog Post February 14, 2022 Learn More

Novel antibody tests reveal complexity of immune response to covid-19

Research Highlight February 01, 2021 Learn More

News and Insights

Blog Post February 14, 2022

Systemic Immune Responses - Humanized Mice

Research HighlightFebruary 01, 2021

Novel antibody tests reveal complexity of immune response to covid-19

Blog Post January 20, 2021

Advancing Humanized NSGTM Mice for Immuno-Oncology Testing

Blog Post April 21, 2020

CD34+ Hematopoietic Stem Cell Humanized Mice: The Basics

Press ReleaseJanuary 23, 2020

Small molecules mean big data for health and disease

eNewsOctober 30, 2019

Leveraging our immune systems for good

Press ReleaseAugust 01, 2019

Preventing anaphylaxis

Search MagazineApril 11, 2019

Tipping the balance in the fight against cancer

Related Services

Genome Scanning Service

Breeding Services

Immunology Services

data icon

Most Popular JAX Mice Strains

data icon

Imiquimod-Induced Psoriasis Efficacy Studies

Education Resources

Jul 17 - 28
Short Course

Human and Mammalian Genetics and Genomics: The 64th McKusick Short Course

Precision medicine, Ethics, Stem cells, Microbiome, Infectious Disease, Immunology, Model Development, Rare Diseases, Aging, Cardiovascular, Cancer/Tumors, Developmental Biology, Diabetes, Genetic Tools, Optogenetics and Pharmacogenetics, Autoimmunity, Inflammation, Lupus, Addiction, Dermatology, Autoimmune Diseases Information, Metabolic Diseases, Neurodegenerative Disease, Reproductive Biology, Down Syndrome, Fragile X, Rett Syndrome, Breast Cancer, Neurodevelopmental Defects, Metabolic Defects, Cystic Fibrosis, Genetics and Genomics, Reproductive Disorders, Complex Traits, Developmental Disorders, Diabetes and Obesity, Neurodegenerative and Neuromuscular Diseases, Immune Disorders, Bioinformatics, Computational Biology, Cancer
Aug 14 - 22
Short Course

32nd Annual Short Course on Experimental Models of Human Cancer

Sep 11 - 13
Workshop

Workshop on Vascular Catheterization in the Laboratory Mouse

Model Development, Genetic Tools, Genetics and Genomics, Resource Development and Dissemination
Sep 14 - 15
Workshop

Systems Immunology in Aging and Complex Diseases

Research & Faculty

Biology of Beta Cell Consortium

NOD-scid IL2rgnull (NSG) and NOD-Rag1null IL2rgnull (NRG) mice support heightened levels of engraftment with human cells and tissues. These engrafted mice allow research on human disease processes without putting individuals at risk.

Chun Yu, Ph.D.

Chun Yu, Ph.D.

Associate Research Scientist

Immune Disorders

Researching the basic biology of the immune response, autoimmunity, the role of the immune system in glaucoma, cancer and other diseases, and more.

Guangwen "Gary" Ren, Ph.D.

Guangwen "Gary" Ren, Ph.D.

Associate Professor

Mouse Genome Informatics

International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.

Jeffrey Harder, Ph.D.

Jeffrey Harder, Ph.D.

Associate Computational Scientist

The Howell Lab

Investigates the early stages of age-related neurodegenerative diseases.

The Ucar Lab

Develops computational methods to study the epigenetic regulation of gene expression and its implications in important human conditions including aging and common diseases.

The Stitzel Lab

Researches human pancreatic islet cells and the genetic and environmental bases of type 2 diabetes.

The Ringwald Lab

Captures gene expression data and disseminates it to the research community.

The Shultz Lab

Investigates human immunological diseases and malignancy through the development and leveraging of novel humanized mouse models

Michael Stitzel, Ph.D.

Michael Stitzel, Ph.D.

Associate Professor

Mouse Peroxisome Research Resource

The Mouse Peroxisome Research Resource (MPRR) at the Jackson Laboratory serves as a centralized resource for mouse models and monoclonal antibodies for basic and translational research relevant to peroxisome biology and disorders caused by peroxisome dysfunction.

Mouse Mutant Resource

Mice harboring spontaneous mutations have long been a major source for animal models of human genetic disorders, particularly mendelian diseases. The Mouse Mutant Resource maintains over 700 established mutant strains.