Sergii Domanskyi, Ph.D.

Associate Computational Scientist

Development of novel computational, statistical and mathematical approaches for the analysis of Next Generation Sequencing (NGS) data.

I have a strong background in the physical and computational sciences, large-scale computational techniques, and software design, allowing me to model biological systems in multidisciplinary projects. In my post-doctoral research at Michigan State University, I have developed novel statistical and mathematical approaches in open-source packages PyIOmica, DigitalCellSorter, and DECNEO for time-series data analysis and discovery of the combinations of receptors from an extensive collection of single-cell RNA sequencing datasets. Currently, I am developing advanced computational approaches for quality control and downstream analysis of spatially resolved transcriptomics data. I am interested in algorithms exploring tumor growth, development dynamics, and gene expression regulation. I enjoy researching complex processes in the tumor microenvironment to help understand cancer biology questions through the analysis of Next Generation Sequencing data. I help automate and standardize data analysis workflows by creating Nextflow-based computational pipelines using state-of-the-art computational biology methods. My objective is to continue biostatistics analysis, develop bioinformatics algorithms and encapsulate these novel methods in reliable software for personal and HPC systems..

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Sergii Domanskyi on ORCID

Education and experience


Clarkson University, Potsdam, NY
Ph.D., Physics
Adv: Prof. Vladimir Privman

National Technical University of Ukraine, Kyiv, Ukraine
Master of Science, Physics
Adv: Prof. Vyacheslav Gorshkov

National Technical University of Ukraine, Kyiv, Ukraine
Bachelor of Science, Physics


Assistant Computational Scientist
The Jackson Laboratory, Bar Harbor, ME

Post-Doctoral Research Associate
Michigan State University, East Lansing, MI

Visiting Graduate Student Researcher
Los Alamos National Laboratory, Los Alamos, NM
2015, 2016

Research and Teaching Assistant
Clarkson University, Potsdam, NY

Software Designer
Consulting and Information Technology, LLC, Kyiv, Ukraine