Neurodegenerative Disease

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The Cox Lab

Researches the molecular pathways of human degenerative muscle diseases.

Cynthia Smith, Ph.D.

Research Scientist

David Hill, Ph.D.

Research Scientist

Jacqui White, Ph.D.

Director, Center for Biometric Analysis

James Kadin, Ph.D.

Senior Research Scientist

Jürgen Naggert, Ph.D.

Professor

The Ke Lab

Ke Lab studies RNA from birth to death during organism neurological development, and its malfunctions in diseases for effective therapies in clinics.

Kenneth Fasman, Ph.D.

Senior Vice President for Research

Laurent Bogdanik, Ph.D., M.B.A.

Study Director

Michael Sasner, Ph.D.

Research Scientist

Molly Bogue, Ph.D.

Research Scientist

Mouse Genome Informatics

International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.

Parkinson's Disease Mouse Model Resource

The Parkinson’s Disease Mouse Model Resource characterizes and distributes new mouse models of Parkinsonism and Parkinson’s disease.

Peripheral Neuropathy Resource

Serves as a centralized resource for mouse models and tools that have been validated for use in preclinical studies of peripheral neuropathy.

Jax Mice & Services

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Neurodegenerative Disease

News and Insights

Related Services

Education Resources

Research & Faculty

Jax Mice & Services

014631SWR/J-Clec16acurt/GrsrJ

017766(C57BL/6J x SWR/J-Clec16acurt/GrsrJ)F1

024854STOCK Tg(Camk2a-tTA)1Mmay Fgf14Tg(tetO-MAPT*P301L)4510Kha/J

008169B6;C3-Tg(Prnp-MAPT*P301S)PS19Vle/J

027410B6J.129S1-Htttm1Mfc/190ChdiJ

004938FVB-Tg(YAC128)53Hay/J

007051B6.Cg-Tg(tetO-APPSwInd)102Dbo/Mmjax

027421B6J.Cg-Tg(HDexon1)62Gpb/160ChdiJ

027426B6.Cg-Gt(ROSA)26Sortm51(HTT)Arte/ChdiJ

006823B6.Cg-2310039L15RikTg(Prnp-SNCA*A53T)23Mkle/J

027432B6.FVB-Tg(YAC128)53Hay/ChdiJ

012705B6;CBA-Tg(ATXN3*)84.2Cce/IbezJ

031671FVB/N-Tg(GFAP-tTA)6Hyms Tg(tetO-HMOX1)6Hyms/J

015815FVB-Fgf14Tg(tetO-MAPT*P301L)4510Kha/JlwsJ

007052B6.Cg-Tg(tetO-APPSwInd)107Dbo/Mmjax

027422D2.Cg-Tg(HDexon1)62Gpb/160ChdiJ

027411B6.129S1(Cg)-Htttm2Mem/20ChdiJ

005058FVB.Cg-Smn1tm1Hung Tg(SMN2)2Hung/J

027424D2.Cg-Tg(HDexon1)62Gpb/240ChdiJ

024841B6N.Cg-Tg(Prnp-MAPT*P301S)PS19Vle/J

370476B6J.129S1-Htttm1Mfc/190JChdi

027409B6J.129S1-Htttm1Mfc/140ChdiJ

027412B6.129S4-Htttm1.1Pfs/80ChdiJ

027425D2.Cg-Tg(HDexon1)62Gpb/280ChdiJ

027429B6.Cg-Gt(ROSA)26Sortm48(HTT)Arte/ChdiJ

027428B6.Cg-Gt(ROSA)26Sortm49(HTT)Arte/ChdiJ

027423B6J.Cg-Tg(HDexon1)62Gpb/240ChdiJ

005706C57BL/6-Tg(tetO-CDK5R1/GFP)337Lht/J

027419B6J.Cg-Tg(HDexon1)62Gpb/110ChdiJ

027427B6.Cg-Gt(ROSA)26Sortm50(HTT)Arte/ChdiJ

017483FVB-Tg(JPH3*)CXwy/J

005934B6.129S4-Ucp2tm1Lowl/J

008843B6.129P2-Sncgtm1Vlb/J

028559B6(Cg)-Sncatm1.2Vlb/J

012769C57BL/6-Tg(Thy1-Sncg)HvP36Putt/J

017459B6.Cg-Mapttm1Hnd Tg(MAPT*)1Gds/Mmjax

027414B6N.Cg-Htttm2Xen/45ChdiJ

027418B6N.Cg-Htttm6Xen/105ChdiJ

015852B6.Cg-Mapttm1Hnd Tg(MAPT*S305S)4Gds/Mmjax

027435B6.Cg-Htttm1(HTT)Arte/ChdiJ

008601B6.Cg-7630403G23RikTg(Th-cre)1Tmd/J

017326B6.Cg-Mapttm1Hnd Tg(MAPT)1Gds/Mmjax

027416B6N.Cg-Htttm4Xen/80ChdiJ

012588B6.Cg-Tg(TH-ALPP)1Erav/J

017798B6.Cg-Mapttm1Hnd Tg(Thy1-MAPT*)3610Gds/Mmjax

017797B6.Cg-Mapttm1Hnd Tg(Thy1-MAPT*)3608Gds/Mmjax

025636B6(Cg)-Sncatm1.1Vlb/J

017545B6.Cg-Mapttm1Hnd Tg(MAPT*V337M)1Gds/Mmjax

014631
SWR/J-Clec16a^curt/GrsrJ

017766
(C57BL/6J x SWR/J-Clec16a^curt/GrsrJ)F1

024854
STOCK Tg(Camk2a-tTA)1Mmay Fgf14^{Tg(tetO-MAPTP301L)4510Kha}*/J

008169
B6;C3-Tg(Prnp-MAPT*P301S)PS19Vle/J

027410
B6J.129S1-Htt^tm1Mfc/190ChdiJ

004938
FVB-Tg(YAC128)53Hay/J

007051
B6.Cg-Tg(tetO-APPSwInd)102Dbo/Mmjax

027421
B6J.Cg-Tg(HDexon1)62Gpb/160ChdiJ

027426
B6.Cg-Gt(ROSA)26Sor^{tm51(HTT)Arte}/ChdiJ

006823
B6.Cg-2310039L15Rik^{Tg(Prnp-SNCAA53T)23Mkle}*/J

027432
B6.FVB-Tg(YAC128)53Hay/ChdiJ

012705
B6;CBA-Tg(ATXN3*)84.2Cce/IbezJ

031671
FVB/N-Tg(GFAP-tTA)6Hyms Tg(tetO-HMOX1)6Hyms/J

015815
FVB-Fgf14^{Tg(tetO-MAPTP301L)4510Kha}*/JlwsJ

007052
B6.Cg-Tg(tetO-APPSwInd)107Dbo/Mmjax

027422
D2.Cg-Tg(HDexon1)62Gpb/160ChdiJ

027411
B6.129S1(Cg)-Htt^tm2Mem/20ChdiJ

005058
FVB.Cg-Smn1^tm1Hung Tg(SMN2)2Hung/J

027424
D2.Cg-Tg(HDexon1)62Gpb/240ChdiJ

024841
B6N.Cg-Tg(Prnp-MAPT*P301S)PS19Vle/J

370476
B6J.129S1-Htt^tm1Mfc/190JChdi

027409
B6J.129S1-Htt^tm1Mfc/140ChdiJ

027412
B6.129S4-Htt^tm1.1Pfs/80ChdiJ

027425
D2.Cg-Tg(HDexon1)62Gpb/280ChdiJ

027429
B6.Cg-Gt(ROSA)26Sor^{tm48(HTT)Arte}/ChdiJ

027428
B6.Cg-Gt(ROSA)26Sor^{tm49(HTT)Arte}/ChdiJ

027423
B6J.Cg-Tg(HDexon1)62Gpb/240ChdiJ

005706
C57BL/6-Tg(tetO-CDK5R1/GFP)337Lht/J

027419
B6J.Cg-Tg(HDexon1)62Gpb/110ChdiJ

027427
B6.Cg-Gt(ROSA)26Sor^{tm50(HTT)Arte}/ChdiJ

017483
FVB-Tg(JPH3*)CXwy/J

005934
B6.129S4-Ucp2^tm1Lowl/J

008843
B6.129P2-Sncg^tm1Vlb/J

028559
B6(Cg)-Snca^tm1.2Vlb/J

012769
C57BL/6-Tg(Thy1-Sncg)HvP36Putt/J

017459
B6.Cg-Mapt^tm1Hnd Tg(MAPT*)1Gds/Mmjax

027414
B6N.Cg-Htt^tm2Xen/45ChdiJ

027418
B6N.Cg-Htt^tm6Xen/105ChdiJ

015852
B6.Cg-Mapt^tm1Hnd Tg(MAPT*S305S)4Gds/Mmjax

027435
B6.Cg-Htt^tm1(HTT)Arte/ChdiJ

008601
B6.Cg-7630403G23Rik^{Tg(Th-cre)1Tmd}/J

017326
B6.Cg-Mapt^tm1Hnd Tg(MAPT)1Gds/Mmjax

027416
B6N.Cg-Htt^tm4Xen/80ChdiJ

012588
B6.Cg-Tg(TH-ALPP)1Erav/J

017798
B6.Cg-Mapt^tm1Hnd Tg(Thy1-MAPT*)3610Gds/Mmjax

017797
B6.Cg-Mapt^tm1Hnd Tg(Thy1-MAPT*)3608Gds/Mmjax

025636
B6(Cg)-Snca^tm1.1Vlb/J

017545
B6.Cg-Mapt^tm1Hnd Tg(MAPT*V337M)1Gds/Mmjax