Neurodegenerative Disease

The Jackson Laboratory addresses a wide range for research topics regarding neurological function and dysfunction, from developmental processes and sensory disorders to neuron degeneration.

Virtual forum: Finding resilience-based targets for Alzheimer's disease

Featured Article October 01, 2020 Learn More

How to address secondary findings from genomic testing

Blog Post June 22, 2020 Learn More

News and Insights

Featured ArticleOctober 01, 2020

Virtual forum: Finding resilience-based targets for Alzheimer's disease

Blog Post June 21, 2020

How to address secondary findings from genomic testing

Search MagazineDecember 01, 2019

Mighty Mice in the classroom

Blog Post May 31, 2019

The Versatile Mouse Model for Rare Disease Research

Research HighlightMarch 07, 2019

Long-range connectivity and gene regulation networks

Press ReleaseDecember 27, 2018

New Alzheimer's mouse models show how human diversity affects disease onset

Research HighlightDecember 14, 2018

Gene knockdown induces deficits reminiscent of aging and Alzheimer's

Blog Post December 11, 2018

600 trillion synapses and Alzheimers disease

Related Services

Most popular JAX Mice strains

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Breeding Services

Mouse Biospecimens

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Education Resources

Jan 25 - 27

(Postponed - Dates TBD) Workshop on Stereotaxic Surgery in the Laboratory Mouse

Apr 26 - 30
Workshop

Principles and Techniques for Improving Preclinical to Clinical Translation in Alzheimer's Disease Research

Jun 21 - 23
Workshop

Workshop on Stereotaxic Surgery in the Laboratory Mouse (in Paris, France)

Model Development, Neuroscience, Neurodevelopmental Defects, Neurodegenerative and Neuromuscular Diseases
Jul 18 - 28
Short Course

Human and Mammalian Genetics and Genomics: The 63rd McKusick Short Course

Precision medicine, Ethics, Stem cells, Microbiome, Infectious Disease, Immunology, Model Development, Rare Diseases, Aging, Cardiovascular, Cancer/Tumors, Developmental Biology, Diabetes, Genetic Tools, Optogenetics and Pharmacogenetics, Autoimmunity, Inflammation, Lupus, Addiction, Dermatology, Autoimmune Diseases Information, Metabolic Diseases, Neurodegenerative Disease, Reproductive Biology, Down Syndrome, Fragile X, Rett Syndrome, Breast Cancer, Neurodevelopmental Defects, Metabolic Defects, Cystic Fibrosis, Genetics and Genomics, Reproductive Disorders, Complex Traits, Developmental Disorders, Diabetes and Obesity, Neurodegenerative and Neuromuscular Diseases, Immune Disorders, Bioinformatics, Computational Biology, Cancer
Jul 18 - 28
Virtual Event or Webinar

Virtual Event - Human and Mammalian Genetics and Genomics: The 63rd McKusick Short Course

Precision medicine, Ethics, Stem cells, Microbiome, Infectious Disease, Immunology, Model Development, Rare Diseases, Aging, Cardiovascular, Cancer/Tumors, Developmental Biology, Diabetes, Genetic Tools, Optogenetics and Pharmacogenetics, Autoimmunity, Inflammation, Lupus, Addiction, Dermatology, Autoimmune Diseases Information, Metabolic Diseases, Neurodegenerative Disease, Reproductive Biology, Down Syndrome, Fragile X, Rett Syndrome, Breast Cancer, Neurodevelopmental Defects, Metabolic Defects, Cystic Fibrosis, Genetics and Genomics, Reproductive Disorders, Complex Traits, Developmental Disorders, Diabetes and Obesity, Neurodegenerative and Neuromuscular Diseases, Immune Disorders, Bioinformatics, Computational Biology, Cancer
Aug 16 - 18

Workshop on Stereotaxic Surgery in the Laboratory Mouse

Research & Faculty

The Cox Lab

Researches the molecular pathways of human degenerative muscle diseases.

Cynthia Smith, Ph.D.

Cynthia Smith, Ph.D.

Research Scientist

David Hill, Ph.D.

David Hill, Ph.D.

Research Scientist

Jacqui White, Ph.D.

Jacqui White, Ph.D.

Director, Center for Biometric Analysis

James Kadin, Ph.D.

James Kadin, Ph.D.

Senior Research Scientist

Jürgen Naggert, Ph.D.

Jürgen Naggert, Ph.D.

Professor

Kenneth Fasman, Ph.D.

Kenneth Fasman, Ph.D.

Senior Vice President for Research

Laurent Bogdanik, Ph.D., M.B.A.

Laurent Bogdanik, Ph.D., M.B.A.

Study Director

Michael Sasner, Ph.D.

Michael Sasner, Ph.D.

Senior Research Scientist

Molly Bogue, Ph.D.

Molly Bogue, Ph.D.

Research Scientist

Mouse Genome Informatics

International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.

Parkinson's Disease Mouse Model Resource

The Parkinson’s Disease Mouse Model Resource characterizes and distributes new mouse models of Parkinsonism and Parkinson’s disease.

Peripheral Neuropathy Resource

Serves as a centralized resource for mouse models and tools that have been validated for use in preclinical studies of peripheral neuropathy.

Jax Mice & Services

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JAX Mice Stock Number 017766

017766
(C57BL/6J x SWR/J-Clec16acurt/GrsrJ)F1

JAX Mice Stock Number 014631

014631
SWR/J-Clec16acurt/GrsrJ

JAX Mice Stock Number 008169

008169
B6;C3-Tg(Prnp-MAPT*P301S)PS19Vle/J

JAX Mice Stock Number 024854

024854
STOCK Tg(Camk2a-tTA)1Mmay Fgf14Tg(tetO-MAPT*P301L)4510Kha/J

JAX Mice Stock Number 027410

027410
B6J.129S1-Htttm1Mfc/190ChdiJ

JAX Mice Stock Number 004938

004938
FVB-Tg(YAC128)53Hay/J

JAX Mice Stock Number 007051

007051
B6.Cg-Tg(tetO-APPSwInd)102Dbo/Mmjax

JAX Mice Stock Number 027421

027421
B6J.Cg-Tg(HDexon1)62Gpb/160ChdiJ

JAX Mice Stock Number 027426

027426
B6.Cg-Gt(ROSA)26Sortm51(HTT)Arte/ChdiJ

JAX Mice Stock Number 027432

027432
B6.FVB-Tg(YAC128)53Hay/ChdiJ

JAX Mice Stock Number 006823

006823
B6.Cg-2310039L15RikTg(Prnp-SNCA*A53T)23Mkle/J

JAX Mice Stock Number 015815

015815
FVB-Fgf14Tg(tetO-MAPT*P301L)4510Kha/JlwsJ

JAX Mice Stock Number 005058

005058
FVB.Cg-Smn1tm1Hung Tg(SMN2)2Hung/J

JAX Mice Stock Number 007052

007052
B6.Cg-Tg(tetO-APPSwInd)107Dbo/Mmjax

JAX Mice Stock Number 027422

027422
D2.Cg-Tg(HDexon1)62Gpb/160ChdiJ

JAX Mice Stock Number 012705

012705
B6;CBA-Tg(ATXN3*)84.2Cce/IbezJ

JAX Mice Stock Number 027409

027409
B6J.129S1-Htttm1Mfc/140ChdiJ

JAX Mice Stock Number 005706

005706
C57BL/6-Tg(tetO-CDK5R1/GFP)337Lht/J

JAX Mice Stock Number 027419

027419
B6J.Cg-Tg(HDexon1)62Gpb/110ChdiJ

JAX Mice Stock Number 027412

027412
B6.129S4-Htttm1.1Pfs/80ChdiJ

JAX Mice Stock Number 027428

027428
B6.Cg-Gt(ROSA)26Sortm49(HTT)Arte/ChdiJ

JAX Mice Stock Number 027429

027429
B6.Cg-Gt(ROSA)26Sortm48(HTT)Arte/ChdiJ

JAX Mice Stock Number 031671

031671
FVB/N-Tg(GFAP-tTA)6Hyms Tg(tetO-HMOX1)6Hyms/J

JAX Mice Stock Number 027424

027424
D2.Cg-Tg(HDexon1)62Gpb/240ChdiJ

JAX Mice Stock Number 024841

024841
B6N.Cg-Tg(Prnp-MAPT*P301S)PS19Vle/J

JAX Mice Stock Number 027427

027427
B6.Cg-Gt(ROSA)26Sortm50(HTT)Arte/ChdiJ

JAX Mice Stock Number 027425

027425
D2.Cg-Tg(HDexon1)62Gpb/280ChdiJ

JAX Mice Stock Number 027411

027411
B6.129S1(Cg)-Htttm2Mem/20ChdiJ

JAX Mice Stock Number 027423

027423
B6J.Cg-Tg(HDexon1)62Gpb/240ChdiJ

JAX Mice Stock Number 370476

370476
B6J.129S1-Htttm1Mfc/190JChdi

JAX Mice Stock Number 017483

017483
FVB-Tg(JPH3*)CXwy/J

JAX Mice Stock Number 005934

005934
B6.129S4-Ucp2tm1Lowl/J

JAX Mice Stock Number 008843

008843
B6.129P2-Sncgtm1Vlb/J

JAX Mice Stock Number 028559

028559
B6(Cg)-Sncatm1.2Vlb/J

JAX Mice Stock Number 012769

012769
C57BL/6-Tg(Thy1-Sncg)HvP36Putt/J

JAX Mice Stock Number 017459

017459
B6.Cg-Mapttm1Hnd Tg(MAPT*)1Gds/Mmjax

JAX Mice Stock Number 015852

015852
B6.Cg-Mapttm1Hnd Tg(MAPT*S305S)4Gds/Mmjax

JAX Mice Stock Number 012588

012588
B6.Cg-Tg(TH-ALPP)1Erav/J

JAX Mice Stock Number 017326

017326
B6.Cg-Mapttm1Hnd Tg(MAPT)1Gds/Mmjax

JAX Mice Stock Number 017797

017797
B6.Cg-Mapttm1Hnd Tg(Thy1-MAPT*)3608Gds/Mmjax

JAX Mice Stock Number 017798

017798
B6.Cg-Mapttm1Hnd Tg(Thy1-MAPT*)3610Gds/Mmjax

JAX Mice Stock Number 008601

008601
B6.Cg-7630403G23RikTg(Th-cre)1Tmd/J

JAX Mice Stock Number 025636

025636
B6(Cg)-Sncatm1.1Vlb/J

JAX Mice Stock Number 017545

017545
B6.Cg-Mapttm1Hnd Tg(MAPT*V337M)1Gds/Mmjax

JAX Mice Stock Number 008333

008333
B6;129P2-Dldtm1Ptl/J

JAX Mice Stock Number 029855

029855
STOCK Sncatm1.1Vlb Gt(ROSA)26Sortm1Sho/J

JAX Mice Stock Number 028560

028560
STOCK Sncatm1.2Vlb Gt(ROSA)26Sortm1Sho/J

JAX Mice Stock Number 007004

007004
B6.Cg-Tg(Camk2a-tTA)1Mmay/DboJ