Jackson Laboratory

Neurodegenerative Disease

The Jackson Laboratory addresses a wide range for research topics regarding neurological function and dysfunction, from developmental processes and sensory disorders to neuron degeneration.

News and Insights

Press ReleaseSeptember 18, 2017

New $5.4M grant funds JAX studies of ‘cognitive resilience’ to Alzheimer’s disease

Press ReleaseMarch 30, 2017

JAX researchers identify mutations in Charcot-Marie-Tooth disease that worsen peripheral nerve damage

The Search Magazine ArticleFebruary 28, 2017

Our mouse model paved the way for a new SMA drug

Press ReleaseAugust 17, 2016

NIH grant will fund new JAX resource for peripheral neuropathy research

eNewsAugust 17, 2016

MicroRNAs and Parkinson's Disease

Press ReleaseMay 09, 2016

New insight in sphingolipid formation reveals neurodegenerative process

eNewsMay 08, 2016

Memory loss reversed in mouse models of early Alzheimer’s Disease

eNewsApril 12, 2016

Reduced MeCP2 signaling leads to hypoalgesia in a mouse model of Rett syndrome

Related Services

Neurobiology

Most popular JAX Mice strains

Breeding Services

Mouse Biospecimens

Education Resources

Oct 22 - 28

Workshop

Principles and Techniques in Mouse Behavioral Phenotyping and Pharmacology

Model Development, Neurodegenerative Disease, Neuroscience, Behavioral and Cognitive Impairment, Optogenetics and Pharmacogenetics, Ataxia Movement Defects, Neuromuscular Defects, Autism, Learning deficits, Rett Syndrome, Neurodevelopmental Defects, Behavioral Disorders, Complex Traits, Developmental Disorders, Neurodegenerative and Neuromuscular Diseases, Resource Development and Dissemination

Oct Nov 30 - 03

Short Course

21st Century Mouse Genetics

Genetic Tools, Model Development, Neurodegenerative Disease, Rare Diseases, Reproductive Biology, Aging, Developmental Biology, Cancer/Tumors, Diabetes, Bioinformatics, Complex Traits, Cancer, Computational Biology, Genetics and Genomics

Aug 24 - 31

Workshop

Workshop on Techniques in Modeling Human Cancer in Mice

Endocrinology, Genetic Tools, Rare Diseases, Neurodegenerative Disease, Cancer/Tumors, Genetics and Genomics, Cancer

Sep 17 - 21

Workshop

Principles and Techniques in Mouse Behavioral Phenotyping and Pharmacology

Model Development, Neurodegenerative Disease, Neuroscience, Behavioral and Cognitive Impairment, Optogenetics and Pharmacogenetics, Ataxia Movement Defects, Neuromuscular Defects, Autism, Learning deficits, Rett Syndrome, Neurodevelopmental Defects, Behavioral Disorders, Complex Traits, Developmental Disorders, Neurodegenerative and Neuromuscular Diseases, Resource Development and Dissemination

Oct Nov 29 - 02

Short Course

21st Century Mouse Genetics

Genetic Tools, Model Development, Neurodegenerative Disease, Rare Diseases, Reproductive Biology, Aging, Developmental Biology, Cancer/Tumors, Diabetes, Bioinformatics, Complex Traits, Cancer, Computational Biology, Genetics and Genomics

Research & Faculty

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Amy N. Hicks, Ph.D.

Postdoctoral Associate

The Cox Lab

Researches the molecular pathways of human degenerative muscle diseases.

Cynthia Smith, Ph.D.

Research Scientist

David Hill, Ph.D.

Research Scientist

Jacqui White, Ph.D.

Director, Center for Biometric Analysis

James Kadin, Ph.D.

Senior Research Scientist

Jurgen Naggert, Ph.D.

Professor

Kenneth Johnson, Ph.D.

Associate Professor

Kevin Seburn, Ph.D.

Research Scientist

Laurent Bogdanik, Ph.D., M.B.A.

Study Director

Michael Sasner, Ph.D.

Research Scientist

Molly Bogue, Ph.D.

Research Scientist

Mouse Genome Informatics

International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.

Mouse Genome Informatics

International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.

The Ouyang Lab

Models genome regulation using computational and statistical methods.

Parkinson's Disease Mouse Model Resource

The Parkinson’s Disease Mouse Model Resource characterizes and distributes new mouse models of Parkinsonism and Parkinson’s disease.

Peripheral Neuropathy Resource

Serves as a centralized resource for mouse models and tools that have been validated for use in preclinical studies of peripheral neuropathy.

Simon John, Ph.D.

Professor and Howard Hughes Medical Investigator

Yair Dorsett, Ph.D.

Associate Research Scientist

Zhengqing Ouyang, Ph.D.

Assistant Professor