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Research HighlightMarch 18, 2020Raising the bar for PDX model cancer research
The results of a new PDXNet consortium study provide a key validation toward translating xenograft findings into clinical treatments for cancer patients. -
Press ReleaseMarch 11, 2020The gene lexicologist
ISCB honors JAX Professor Judith Blake for outstanding contributions to biology -
Blog PostMarch 04, 2020Building in silico research models to accelerate discovery
Machine learning and deep learning in particular have a growing influence on everything from how we shop to how we drive—or are driven by self-driving cars. Anshul Kundaje, Ph.D., assistant professor of genetics and computer science at Stanford University, is using similar tools to study large-scale computational regulatory genomics. -
Research HighlightFebruary 24, 2020Gene silencers and their vital roles in development
New research shows that silencers modify 3D chromatin organizations to suppress the expression of certain genes at certain time points during development. Disruption of the process can lead to developmental disorders and has also been implicated in certain cancers.
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Press ReleaseMarch 17, 2020NSF CAREER award to Beth Dumont of JAX
Prestigious five-year grant funds evolutionary genomics research, educational outreach. -
Press ReleaseMarch 10, 2020Sheng Li named an AACR NextGen Star
Jackson Laboratory (JAX) Assistant Professor Sheng Li, Ph.D., was chosen as a 2020 NextGen Star by the American Association for Cancer Research (AACR). She is one of 12 early-career cancer researchers recognized for their outstanding work and future potential. -
Research HighlightMarch 03, 2020Unfolding the 3D genome
Three-dimensional genomic compartments and sub-compartments help regulate gene expression across the genome. As more data comes out about 3D genomic structures, there is an increasing need to efficiently identify and characterize sub-compartments and their roles in genome function. Sheng Li and her team developed a new computational tool, SCI, that outperforms previously developed algorithms for this purpose. -
Press ReleaseJanuary 30, 2020Advancing genomics for pediatric orthopedic diseases
Shriners Hospitals for Children and The Jackson Laboratory announce research affiliation for genomic studies of pediatric patients.