I joined the Simon John lab in the spring of 2013, excited by the opportunity of working with Dr. John and using a multidisciplinary approach in my research. Using DBA/2J mice as a model of glaucoma, my current research focuses on axon degeneration, the role of innate immunity in the central nervous system, and the role of diet in neurodegeneration. This includes studying the role of JNKs in glaucomatous injury and working to identify early signaling events that may initiate injury. For another project, I am collaborating with faculty from Dalhousie University, working on defining human genes responsible for exfoliation syndrome glaucoma. I also work closely with fellow postdoc Pete Williams and help direct two research assistants in the lab. This opportunity to collaborate and manage while working through complex projects is broadening my conceptual thinking abilities both scientifically and managerially, and improving the array of skill sets necessary for running a lab.
2014 The Barbara and Joseph Cohen Endowmen
2013 Immunology Training Fellowship, The Jackson Laboratory
2011 National Eye Institute Travel Grant, ARVO
2011 Pathology Research Day Poster Award, University of Rochester Medical School.
2008 Vision Training Fellowship, University of Rochester.
2007 Pathology Graduate Program Award, University of Rochester Medical School.
2001 Awarded Scholars Medal by Schreyers Honor College, Pennsylvania State University, University Park, PA.
I'm interested in using computational biology to understand how genetic variation influences diseases and aging.
Model disease through aligning human-mouse phenotype data : case study in Alzheimer disease (AD)
The importance of understanding the role of vaccinations and the ways in which they can be improved.
Researches human pancreatic islet cells and the genetic and environmental bases of type 2 diabetes.
Investigates the early stages of age-related neurodegenerative diseases.
Captures gene expression data and disseminates it to the research community.
Understanding the complex genetic architecture of human disease traits.
Studying genetic variation and its effects on cellular phenotypes and observable traits. Developing statistical models to...
My research interests are in developing computational and statistical methods for analyzing high-throughput genomic data and utilize to...
Leverages advanced technologies to investigate infectious diseases, human and other mammalian microbiomes, and their...
Genetic component dissection for complex human diseases via integrative analysis of diverse genetic and genomic data; method development...
Conducting research that strives to correlate microbial changes to specific effects on human health.
If movies were true to real life, matryoshka dolls would provide a good analogy for genomics research.
Develops computational methods to study the epigenetic regulation of gene expression and its implications in important human conditions...
My research mainly lies in developing and applying statistical and system computational approaches to discover complex disease mechanisms,...
Bridges the digital biology divide, by integrating computation and informatics with biomedical research.