Debbie Krupke

Senior Scientific Curator

Senior Scientific Curator on the Mouse Models of Human Cancer Database (MMHCdb)

I work as a Senior Scientific Curator on the Mouse Models of Human Cancer Database (MMHCdb) (formerly known as the Mouse Tumor Biology (MTB) Database). The MMHCdb is part of the Mouse Genome Informatics (MGI) group here at The Jackson Laboratory.

Education

Johns Hopkins University - BA, Biology (1990)
University of Maine - MS, Microbiology (1994)

Selected Publications

18 Conte N, Mason JC, Halmagyi C, Neuhauser S, Mosaku A, Yordanova G, Chatzipli A, Begley DA, Krupke DM, Parkinson H, Meehan TF, Bult CC. PDX Finder: A portal for patient-derived tumor xenograft model discovery. Nucleic Acids Res. 2019 Jan 8; 47(D1):D1073-D1079
15 Krupke DM, Begley DA, Sundberg JP, Richardson JE, Neuhauser SB, Bult CJ. The Mouse Tumor Biology Database: A Comprehensive Resource for Mouse Models of Human Cancer. Cancer Res. 2017 Nov 1; 77(21):e67-e70
15 Meehan TF, Conte N, Goldstein T, Inghirami G, Murakami MA, Brabetz S, Gu Z, Wiser JA, Dunn P, Begley DA, Krupke DM, Bertotti A, Bruna A, Brush MH, Byrne AT, Caldas C, Christie AL, Clark DA, Dowst H, Dry JR, Doroshow JH, Duchamp O, Evrard YA, Ferretti S, Frese KK, Goodwin NC, Greenawalt D, Haendel MA, Hermans E, Houghton PJ, Jonkers J, Kemper K, Khor TO, Lewis MT, Lloyd KCK, Mason J, Medico E, Neuhauser SB, Olson JM, Peeper DS, Rueda OM, Seong JK, Trusolino L, Vinolo E, Wechsler-Reya RJ, Weinstock DM, Welm A, Weroha SJ, Amant F, Pfister SM, Kool M, Parkinson H, Butte AJ, Bult CJ. PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models. Cancer Res. 2017 Nov 1; 77(21):e62-e66
35 Begley DA, Sundberg JP, Krupke DM, Neuhauser SB, Bult CJ, Eppig JT, Morse HC 3rd, Ward JM. Finding mouse models of human lymphomas and leukemia's using the Jackson laboratory mouse tumor biology database. Exp Mol Pathol. 2015 Dec; 99(3):533-6
46 Bult CJ, Krupke DM, Begley DA, Richardson JE, Neuhauser SB, Sundberg JP, Eppig JT. Mouse Tumor Biology (MTB): a database of mouse models for human cancer. Nucleic Acids Res. 2015 Jan; 43(Database issue):D818-24
23 Begley DA, Krupke DM, Neuhauser SB, Richardson JE, Schofield PN, Bult CJ, Eppig JT, Sundberg JP. Identifying mouse models for skin cancer using the Mouse Tumor Biology Database. Exp Dermatol. 2014 Oct; 23(10):761-3
22 Begley DA, Krupke DM, Neuhauser SB, Richardson JE, Bult CJ, Eppig JT, Sundberg JP. The Mouse Tumor Biology Database (MTB): a central electronic resource for locating and integrating mouse tumor pathology data. Vet Pathol. 2012 Jan; 49(1):218-23
35 Krupke DM, Begley DA, Sundberg JP, Bult CJ, Eppig JT. The Mouse Tumor Biology database. Nat Rev Cancer. 2008 Jun; 8(6):459-65
11 Begley DA, Krupke DM, Vincent MJ, Sundberg JP, Bult CJ, Eppig JT. Mouse Tumor Biology Database (MTB): status update and future directions. Nucleic Acids Res. 2007 Jan; 35(Database issue):D638-42
2 Xu H, Krupke D, Blake J, Friedman C. A natural language processing (NLP) tool to assist in the curation of the laboratory Mouse Tumor Biology Database. AMIA Annu Symp Proc. 2006; 2006:1150
0 Krupke D, Näf D, Vincent M, Allio T, Mikaelian I, Sundberg J, Bult C, Eppig J. The Mouse Tumor Biology Database: integrated access to mouse cancer biology data. Exp Lung Res. 2005 Mar; 31(2):259-70
0 Mikaelian I, Nanney LB, Parman KS, Kusewitt DF, Ward JM, Näf D, Krupke DM, Eppig JT, Bult CJ, Seymour R, Ichiki T, Sundberg JP. Antibodies that label paraffin-embedded mouse tissues: a collaborative endeavor. Toxicol Pathol. 2004 Mar-Apr; 32(2):181-91

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Debbie Krupke

Senior Scientific Curator

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Selected Publications