John P. Graham, Ph.D.

Though not obvious, the tissue microenvironment of tumors and visceral fat share many immunological similarities. Both visceral fat and tumors contain a remarkable diversity of immune cell types, and these cells play major roles in tissue homeostasis and malignancy, respectively. In general, we are interested in comparing and contrasting the cellular ecosystem of visceral fat and tumors to provide insights into processes driving the sequelae of obesity and cancer.