Xiurong Cai

Postdoctoral Associate

I am interested in dissecting the development of hematopoietic stem cells in aging and the underlying mechanism.

Visit The Trowbridge Lab

Location

Bar Harbor, ME

Contact

207-288-6000

xiurong.cai@jax.org

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Topics

Aging
Cancer

I have worked in the field of medical oncology and tumor immunology, focusing on the cellular interaction of the immune system with cancer cells and the therapeutic potential of bi-specific antibodies in lymphoma eradication. Now I continue my research journey as a Postdoctoral Associate in the Trowbridge lab to study the aging-associated hematopoietic stem cell expansion and the transition risk of clonal hematopoiesis to myeloid malignancies.

Xiurong Cai on Orcid

Selected Publications

225 Cai X, Tacke F, Guillot A, Liu H. Cholangiokines: undervalued modulators in the hepatic microenvironment. Front Immunol. 2023; 14:1192840
184 Cai X, Guillot A, Liu H. Cellular Senescence in Hepatocellular Carcinoma: The Passenger or the Driver?. Cells. 2022 Dec 29; 12(1)
44 Chen S, Cai X, Liu Y, Shen Y, Guillot A, Tacke F, Tang L, Liu H. The macrophage-associated microRNA-4715-3p / Gasdermin D axis potentially indicates fibrosis progression in nonalcoholic fatty liver disease: evidence from transcriptome and biological data. Bioengineered. 2022 May; 13(5):11740-11751
0 Reimann M, Schrezenmeier J, Richter-Pechanska P, Dolnik A, Hick TP, Schleich K, Cai X, Fan DNY, Lohneis P, Maßwig S, Denker S, Busse A, Knittel G, Flümann R, Childs D, Childs L, Gätjens-Sanchez AM, Bullinger L, Rosenwald A, Reinhardt HC, Schmitt CA. Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas. Blood. 2021 May 20; 137(20):2785-2799
0 Jia C, Yao Z, Lin Z, Zhao L, Cai X, Chen S, Deng M, Zhang Q. circNFATC3 sponges miR-548I acts as a ceRNA to protect NFATC3 itself and suppressed hepatocellular carcinoma progression. J Cell Physiol. 2021 Feb; 236(2):1252-1269
33 Jia CC, Chen YH, Cai XR, Li Y, Zheng XF, Yao ZC, Zhao LY, Qiu DB, Xie SJ, Chen WJ, Liu C, Liu QL, Wu XY, Wang TT, Zhang Q. Efficacy of cytokine-induced killer cell-based immunotherapy for hepatocellular carcinoma. Am J Cancer Res. 2019; 9(6):1254-1265
27 Chen ZH, Zhang XP, Cai XR, Xie SD, Liu MM, Lin JX, Ma XK, Chen J, Lin Q, Dong M, Wu XY, Wen JY, Xu RH. The Predictive Value of Albumin-to-Alkaline Phosphatase Ratio for Overall Survival of Hepatocellular Carcinoma Patients Treated with Trans-Catheter Arterial Chemoembolization Therapy. J Cancer. 2018; 9(19):3467-3478
23 Cai XR, Chen ZH, Liu MM, Lin JX, Zhang XP, Chen J, Lin Q, Ma XK, Wen JY, Xie SD, Wu XY, Dong M. Modified CLIP score with the albumin-bilirubin grade retains prognostic value in HBV-related hepatocellular carcinoma patients treated with trans-catheter arterial chemoembolization therapy. J Cancer. 2018; 9(13):2380-2388
18 Nan J, Xing YF, Hu B, Tang JX, Dong HM, He YM, Ruan DY, Ye QJ, Cai JR, Ma XK, Chen J, Cai XR, Lin ZX, Wu XY, Li X. Endoplasmic reticulum stress induced LOX-1(+ ) CD15(+) polymorphonuclear myeloid-derived suppressor cells in hepatocellular carcinoma. Immunology. 2018 May; 154(1):144-155
31 Cai X, Chen Z, Chen J, Ma X, Bai M, Wang T, Chen X, Wu D, Wei L, Li X, Lin Q, Wen J, Ruan D, Lin Z, Dong M, Wu X. Albumin-to-Alkaline Phosphatase Ratio as an Independent Prognostic Factor for Overall Survival of Advanced Hepatocellular Carcinoma Patients without Receiving Standard Anti-Cancer Therapies. J Cancer. 2018; 9(1):189-197
0 Jiang WH, Deng L, Ye QJ, Cai JR, Cai XR, Li X. Timing of regular egg intake for prevention of egg allergy. J Allergy Clin Immunol. 2018 Jan; 141(1):459-460
56 Hong YF, Chen ZH, Wei L, Ma XK, Li X, Wen JY, Wang TT, Cai XR, Wu DH, Chen J, Ruan DY, Lin ZX, Lin Q, Dong M, Wu XY. Identification of the prognostic value of lymphocyte-to-monocyte ratio in patients with HBV-associated advanced hepatocellular carcinoma. Oncol Lett. 2017 Aug; 14(2):2089-2096

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