I am originally trained as a molecular biologist. I studied HIV pathogenesis, Herpes viruses and pseudotyped viruses in the context of viral replication and cancers of lymphoid cells. This background led me to study B-cell development and DNA repair systems. I have explored various areas in DNA damage and homologous recombination, and immuno- and chemotherapy development using diverse mouse models. I also have experience in scientific services/core facility management.
With the discovery and widespread use of antiretroviral therapies, growing numbers of individuals with HIV are now able to live into advanced age. Nevertheless, growing evidence indicates that these dramatic gains in longevity have also resulted in increased prevalence among the survivors of non-AIDS morbidity and disability, together with acceleration of many underlying aging processes. As a result, individuals involved in HIV care, policy, and research have increasingly had to refocus their efforts from a traditional infectious disease emphasis toward conceptual models grounded in the management of common chronic diseases and geriatric syndromes.