The Resource for Research on Peripheral Neuropathy (RRPN) at The Jackson Laboratory serves as a centralized resource for mouse models and tools that have been validated for use in preclinical studies of peripheral neuropathy. In addition to optimized animal models of disease, this resource will also assist and accelerate such studies by providing both baseline phenotypic data and the standardized protocols/assays needed to generate clinically relevant data.
The mouse strains below represent many of the best resources and models currently available, and all strains are relevant to peripheral neuropathy research. However, not all models listed develop a peripheral neuropathy phenotype. Part of our goal is to improve these models and to develop new models to overcome this limitation.