Gregory Cary, Ph.D.

Bioinformatics Analyst III

Prioritizing candidate drug targets for diseases with complex etiologies

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Location

Bar Harbor, ME

Contact

207-288-6000

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Topics

Aging
Bioinformatics
Genetics and Genomics
Neurodegenerative and Neuromuscular Diseases

My research has focused on the logic of gene expression regulation, particularly in response to stress. In particular, I have utilized and integrated high-dimensional data to address complex questions about regeneration, neurodegeneration, development, and evolution. My role in the Open-AD consortium is to integrate genomic evidence in support of the prioritization and development of new therapeutic targets for the treatment of Alzheimer's disease.

Gregory Cary on ORCID

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Selected Publications

10 Cary GA, Wolff A, Zueva O, Pattinato J, Hinman VF. Analysis of sea star larval regeneration reveals conserved processes of whole-body regeneration across the metazoa. BMC Biol. 2019 Feb 22; 17(1):16
1 Cary GA, Cameron RA, Hinman VF. Genomic resources for the study of echinoderm development and evolution. Methods Cell Biol. 2019; 151:65-88
8 Cary GA, Cameron RA, Hinman VF. EchinoBase: Tools for Echinoderm Genome Analyses. Methods Mol Biol. 2018; 1757:349-369
18 Cary GA, Hinman VF. Echinoderm development and evolution in the post-genomic era. Dev Biol. 2017 Jul 15; 427(2):203-211
10 Cary GA, Cheatle Jarvela AM, Francolini RD, Hinman VF. Genome-wide use of high- and low-affinity Tbrain transcription factor binding sites during echinoderm development. Proc Natl Acad Sci U S A. 2017 Jun 6; 114(23):5854-5861
2 Hinman V, Cary G. The evolution of gene regulation. Elife. 2017 May 12; 6
8 Cary GA, Vinh DB, May P, Kuestner R, Dudley AM. Proteomic Analysis of Dhh1 Complexes Reveals a Role for Hsp40 Chaperone Ydj1 in Yeast P-Body Assembly. G3 (Bethesda). 2015 Sep 21; 5(11):2497-511
8 Garmendia-Torres C, Skupin A, Michael SA, Ruusuvuori P, Kuwada NJ, Falconnet D, Cary GA, Hansen C, Wiggins PA, Dudley AM. Unidirectional P-body transport during the yeast cell cycle. PLoS One. 2014; 9(6):e99428
5 Cary GA, Yoon SH, Torres CG, Wang K, Hays M, Ludlow C, Goodlett DR, Dudley AM. Identification and characterization of a drug-sensitive strain enables puromycin-based translational assays in Saccharomyces cerevisiae. Yeast. 2014 May; 31(5):167-78
5 Cary GA, Cuttler AS, Duda KA, Kusema ET, Myers JA, Tilden AR. Melatonin: neuritogenesis and neuroprotective effects in crustacean x-organ cells. Comp Biochem Physiol A Mol Integr Physiol. 2012 Apr; 161(4):355-60
13 Cary GA, La Spada AR. Androgen receptor function in motor neuron survival and degeneration. Phys Med Rehabil Clin N Am. 2008 Aug; 19(3):479-94, viii

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Education and experience

Education

Carnegie Mellon University
Postdoctoral fellow
Adv: Dr. Veronica Hinman
2014-2020

University of Washington
Ph.D., Molecular and Cellular Biology
Adv: Aimee Dudley
2006-2013

Colby College
B.A., Biology
2000-2004