The ultimate goal of the JAX 4D Nucleome Center is to deliver a Nucleome Positioning System (NPS) for the generation of complex maps of chromatin interaction network in the...
NOD-scid IL2rgnull (NSG) and NOD-Rag1null IL2rgnull (NRG) mice support heightened levels of engraftment with human cells and tissues. These engrafted mice allow research on...
Supports computational approaches to complex problems; develops software applications and platforms that facilitate access, visualization and sharing of data and algorithms...
The Cre Portal contains curated data about all recombinase-containing transgenes and knock-ins developed in mice to provide a comprehensive resource delineating known...
Tools for automatic glomerulus identification and histological quantification from scanned PAS slides
Phenotype and RNAseq data from approx. 200 (B6-Col4a5 KO x DO)F1 mice
Resource lists and describes mouse models for ocular research at JAX.
FusorSV is a data mining-based framework that allows for comprehensive and robust detection of Structural Variations (SV) from next generation sequencing datasets. We built...
The Gene Ontology (GO) project is a collaborative effort to address the need for consistent descriptions of gene products across databases.
Genetic Resource Science initiates and develops resource-generating research. Our team: identifies and implements innovative technologies for genetic research; makes and...
This tool calculates the glomerular filtration rate in mice using the FITC-inulin method
Integrating multi-track Hi-C data for genome-scale reconstruction of 3D chromatin structure
ATAC-seq is a new protocol to capture open chromatin sites by performing adaptor ligation and fragmentation of open chromatin regions. Due to its efficiency in requirement of...
Scientists around the world are working to generate a targeted knockout mutation for every gene in the mouse genome through the Knockout Mouse...
MAV-seq (Management, Analysis, Visualization of Sequence data) is an interactive, user friendly, cross platform, secure, encrypted, automated, customized, centralized,...
International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.
The Mouse Models of Human Cancer Database (formerly, the Mouse Tumor Biology database) integrates data on the frequency, incidence, genetics, and pathology of neoplastic...
Mice harboring spontaneous mutations have long been a major source for animal models of human genetic disorders, particularly mendelian diseases. The Mouse Mutant Resource...
This resource is a collaborative standardized collection of measured data on laboratory mouse strains and populations. Includes baseline phenotype data sets as well as...
This resource provides mouse models for facial, dental, eye, ear and skull development research, as well as mouse models of human craniofacial...
OncoCL, an ontology to describe cancer cell types
The Parkinson’s Disease Mouse Model Resource characterizes and distributes new mouse models of Parkinsonism and Parkinson’s disease.
QuIN (Query tool for Interaction Networks, available at quin.jax.org) is a tool for visualizing, annotating, and querying chromatin interactions derived from technologies...
Random Forest Regression for Epigenetic Length prediction
SeqFold is a tool for RNA secondary structure prediction from experimental data.
The SMSR maintains mice that are important tools for genetic analysis of complex diseases, including consomic strains.
The WORM Human OrthoLogy Explorer is a meta-tool that uses machine learning to predict novel least diverged orthologs (LDOs) by integrating ortholog predictions from 17...
