Jackson Laboratory

Roux Family Center for Genomics and Computational Biology

Enabling scientists to harness the full power of genomic technologies and computational strategies to analyze the human genome.

The Roux Family Center for Genomics and Computational Biology is a virtual center—spanning JAX’s Bar Harbor and Farmington campuses—that serves as a catalyst for collaborative genomics and computational research. This center includes three endowed faculty chair positions and a permanent fund for recruiting expert staff and driving research and discovery at the Laboratory. The center enables scientists to harness the full power of innovative genomic technologies and computational strategies, using them to analyze the human genome and discover new and better ways of preventing and treating disease.

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Faculty & Staff

Professor

Gary Churchill, Ph.D.

Professor

Peter Robinson, M.D., MSc.

Roel Verhaak, Ph.D.

Upcoming Education

Sep 26 - 29

Workshop

Surgical Techniques in the Laboratory Mouse

Model Development, Genetic Tools, Genetics and Genomics, Resource Development and Dissemination

Sep 26 - 29

Short Course

The Whole Scientist

Aging, Behavioral Disorders, Bioinformatics, Cancer, Computational Biology, Complex Traits, Developmental Disorders, Diabetes and Obesity, Eye Research, Genetics and Genomics, Immune Disorders, Skin Disease, Infectious Disease Research, Neurodegenerative and Neuromuscular Diseases, Reproductive Disorders, Resource Development and Dissemination

Oct 08 - 12

Short Course

The Short Course on the Application of Machine Learning for Automated Quantification of Behavior

Lungs Respiratory, Model Development, Resource Development and Dissemination

Oct 16 - 19

Workshop

Workshop on Colony Management & Biomethods

Oct 23 - 26

Hybrid Event

Short Course on the Genetics of Addiction

Mar 25 - 28

Workshop

Workshop on Surgical Techniques in the Laboratory Mouse

Model Development, Genetic Tools, Genetics and Genomics, Resource Development and Dissemination

Online Courses and On-Demand Webinars

Online Courses

Categorizing Cancer Risk

Cancer/Tumors, Precision medicine, Cancer, Genetics and Genomics

Online Courses

Pre-test Decisions and Counseling

Cancer/Tumors, Precision medicine, Cancer, Genetics and Genomics

Online Courses

Interpreting Genetic Test Results

Cancer/Tumors, Precision medicine, Cancer, Genetics and Genomics

Online Courses

Precision Medicine for Your Practice: Somatic Cancer Panel Testing

Precision medicine, Cancer, Genetics and Genomics, Reproductive Disorders

Short Course

Teaching the Genome Generation - New England

S.T.E.M., Ethics, Precision medicine, Genetic Tools, Bioinformatics, Genetics and Genomics

Webinar

Genetics of Addiction

Research Centers & Resources

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4D Nucleome Center

The ultimate goal of the JAX 4D Nucleome Center is to deliver a Nucleome Positioning System (NPS) for the generation of complex maps of chromatin interaction network in the...

DO-AS cohort data

Phenotype and RNAseq data from approx. 200 (B6-Col4a5 KO x DO)F1 mice

I-ATAC

ATAC-seq is a new protocol to capture open chromatin sites by performing adaptor ligation and fragmentation of open chromatin regions. Due to its efficiency in requirement of...

Biology of Beta Cell Consortium

NOD-scid IL2rgnull (NSG) and NOD-Rag1null IL2rgnull (NRG) mice support heightened levels of engraftment with human cells and tissues. These engrafted mice allow research on...

GFR Calculator

This tool calculates the glomerular filtration rate in mice using the FITC-inulin method

Mouse Models of Human Cancer Database (MMHCdb)

The Mouse Models of Human Cancer Database (formerly, the Mouse Tumor Biology database) integrates data on the frequency, incidence, genetics, and pathology of neoplastic...

Computational Sciences

Computational Sciences supports computational approaches to complex problems; develops software applications and platforms that facilitate access, visualization and sharing...

Gene Ontology Consortium

The Gene Ontology (GO) project is a collaborative effort to address the need for consistent descriptions of gene products across databases.

Mouse Resource for Craniofacial Research

This resource provides mouse models for facial, dental, eye, ear and skull development research, as well as mouse models of human craniofacial...

Cre Portal

The Cre Portal contains curated data about all recombinase-containing transgenes and knock-ins developed in mice to provide a comprehensive resource delineating known...

Mouse Phenome Database

This resource is a collaborative standardized collection of measured data on laboratory mouse strains and populations. Includes baseline phenotype data sets as well as...

Digital Pathology Pipeline

Tools for automatic glomerulus identification and histological quantification from scanned PAS slides

Parkinson's Disease Mouse Model Resource

The Parkinson’s Disease Mouse Model Resource characterizes and distributes new mouse models of Parkinsonism and Parkinson’s disease.

Eye Mutant Resource

Describes mouse models for ocular research available at The Jackson Laboratory and provides a list of known mouse mutations that affect vision.

FusorSV

FusorSV is a data mining-based framework that allows for comprehensive and robust detection of Structural Variations (SV) from next generation sequencing datasets. We built...

Genetic Resource Science

Genetic Resource Science initiates and develops resource-generating research. Our team: identifies and implements innovative technologies for genetic research; makes and...

Mouse Genome Informatics

International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.

Voluntary Workplace Genomic Testing

Knockout Mouse Project (KOMP)

Scientists around the world are working to generate a targeted knockout mutation for every gene in the mouse genome through the Knockout Mouse...

Special Mouse Strains Resource

The SMSR maintains mice that are important tools for genetic analysis of complex diseases, including consomic strains.

Mouse Peroxisome Research Resource

The Mouse Peroxisome Research Resource (MPRR) at the Jackson Laboratory serves as a centralized resource for mouse models and monoclonal antibodies for basic and...

Mouse Mutant Resource

Mice harboring spontaneous mutations have long been a major source for animal models of human genetic disorders, particularly mendelian diseases. The Mouse Mutant Resource...

RFR-PEL

Random Forest Regression for Epigenetic Length prediction

QuIN

QuIN (Query tool for Interaction Networks, available at quin.jax.org) is a tool for visualizing, annotating, and querying chromatin interactions derived from technologies...

WORMHOLE

The WORM Human OrthoLogy Explorer is a meta-tool that uses machine learning to predict novel least diverged orthologs (LDOs) by integrating ortholog predictions from 17...