The JAX Cre Repository's aim is to provide the scientific community with a centralized, comprehensive set of well-characterized Cre Driver lines and related information resources. Available strains include Cre expressing strains, inducible Cre strains, Cre reporter strains, and loxP-flanked (floxed) strains.
The Cre Repository is supported by the Office of Research Infrastructure Programs/Office of the Director grant number OD011190 of the National Institutes of Health (NIH). Please reference this grant in citations acknowledging use of the resource.
The JAX Cre Repository uses a lacZ Cre-reporter strain, B6.129S4-Gt(ROSA)26Sortm1Sor/J, to assess cre activity. β-Galactosidase staining of 10.5 dpc embryos is done in whole mount. Because of tissue size, 15.5 dpc embryos, postnatal day 7 pups, and 8 week old adult mice are cryo-sectioned prior to staining of frozen sections.