Recently developed outbred mouse populations, such as the diversity outbred (DO) mice at The Jackson Laboratory (JAX), have created research options that parallel or even exceed human genetic diversity. Research with DO mice offers a full range of genetic diversity, and therefore more generalizability of responses across populations.
Alzheimer’s disease is still poorly understood despite its huge costs and burden. Greg Carter is working at the intersection between patient and mouse research to develop accurate disease models and develop effective therapies.
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