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Blog PostJanuary 15, 2020Want to know what to feed mice?
"Mice need to eat a well-balanced diet” is a simple and accepted fact of research. But what type of options are available, and which is right for the mice in your facility? Here is an overview of the types of diets, formulations, sterilization techniques, and potential research variables involved in mouse diets. -
Blog PostDecember 23, 2019Nude Mice - More than What Meets the Naked Eye
The mouse is arguably the most widely used mammalian model in biomedical research. Among the various mouse models, nude mice were the first immunocompromised strain to be used in research. Despite advances in the field, nude mice remain an essential player in various studies. Here’s a little background on nude mice and how to handle them. -
Research HighlightSeptember 20, 2019An epigenetic eraser
The genome editing tool, Casilio, can be used to efficiently remove methyl groups from DNA and activate expression of methylation-silenced genes in experimental systems. Casilio was created by Jackson Laboratory Assistant Professor Albert Cheng. -
Press ReleaseJuly 15, 2019Research team creates new research models for Snyder-Robinson Syndrome
Two new mouse models created to study neurological developments in Snyder-Robinson Syndrome to advance global understanding of this rare disease.
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Blog PostDecember 23, 2019Genetic testing can decrease but not rule out cancer risk
Breast cancer risk assessment is increasingly included in primary care. As a rule of thumb, approximately 5-10% of individuals with a breast cancer diagnosis will be found to carry a pathogenic variant (mutation). -
Research HighlightOctober 31, 2019Improving transgene research with split selectable markers
JAX Assistant Professor Albert Cheng led a team to develop split selectable markers, a method that can indicate the successful integration of multiple transgenes. -
Tech CornerJuly 17, 2019Improved methods, expanded capabilities: Analyzing cells one at a time
Researchers are able to do many things today that were impossible five, three, even one year ago. Some of the new options are science-fiction-level impressive. -
Tech CornerJune 17, 2019The genome of Eve (the mouse)
C57BL/6—aka Black 6—is the most widely used mouse strain in research. Its reference genome was published in 2003 and has been carefully curated over the years since.