Research Tools: Cre-lox and More
Additional Cre-Lox resources listed below in the Cre-Lox Resources Section
No, generally one copy of cre is sufficient to recombine loxp sites.
iCre is an alternate version of cre designed for improved expression and reduced chances of epigenetic silencing in mammals. Click here for more information.
For this information:
- Read the Detailed Description on the strain datasheet
- Look in the “Genetics” section for “Site of Expression” data
- Read the primary reference
- See if the Cre Repository has characterized this strain
See if the strain datasheet makes a specific recommendation in the Technical Support Section’s “Breeding Considerations”. Generally we recommend that the male be used as the cre carrier unless otherwise indicated on the Strain Datasheet. Please see item 1 in this article for a specific example of a strain where this matters.