The Pera Lab
Principal Investigator
Location
Our laboratory has two main areas of research. We use human pluripotent stem cells to study extrinsic factors that regulate self-renewal, pluripotency and lineage specification during early human development. We also carry out functional genomic analyses in human and mouse pluripotent stem cells to identify genetic factors that influence regeneration and repair in the central nervous system. We are very pleased to be collaborating with the Nishina laboratory on a study of the genetics of macular degeneration, a common cause of blindness in the aging population.
The International Society for Stem Cell Research (ISSCR) is looking to fill a contract position for an Editorial Assistant for Stem Cell Reports, the official journal of the ISSCR. This position will provide administrative assistance to the Editor in Chief Professor Martin Pera and work closely with the Managing Editor.
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Featured ArticleApril 23, 2024Dan Cortes: gearing up for discovery
Dan Cortes multifaceted journey has led him to pioneering stem cell research within the Pera lab, where he explores the intricate genetic landscape underlying neurological diseases and disorders. -
Research HighlightApril 03, 2024Making mice a more powerful research tool
A new protocol sets the stage for researchers to directly compare mouse and human cells, and readily incorporates genetic diversity into mouse-based research to more closely approximate human health conditions. -
Press ReleaseFebruary 14, 2023JAX scientists aim to regenerate light-sensing cells as treatment for eye disease
A generous gift from Ray Sproats will support research into using human stem cells to treat age-related eye disease. -
Research HighlightOctober 20, 2020From one cell to trillions: Exploring early development
JAX researchers are probing the mysteries of pluripotent stem cells; the earliest stages of life.
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Featured ArticleApril 16, 2024Incorporating diverse background genetics to better model human disease
JAX scientists are working to make it more feasible for researchers to incorporate diverse background genetics to better model human disease in mice. -
Featured ArticleNovember 07, 2023The state of biomedicine presented at the Biomedical Innovation and Technology Conference
The current state of biomedicine and its potential for the future in Maine and beyond as presented in the inaugural Biomedical Innovation and Technology (BIT) Conference. -
Search MagazineOctober 26, 2021Reshaping brain cells for Alzheimer's study
By isolating and reprogramming brain cells with dementia-causing genetic mutations, a team at JAX offers a powerful new research tool. -
Search MagazineSeptember 07, 2020Mighty Mice stay mighty in space
In a paper published in the Proceedings of the National Academy of Sciences, researchers show that JAX Mighty Mice stayed relatively mighty during their time in microgravity, while the normal control mice lost considerable muscle mass and bone density.