In Vivo Pharmacology

We offer definitive solutions for basic research and therapeutic development to advance the fields of oncology, immunology, and neurobiology.  We provide the most robust and innovative humanized pre-clinical models and efficacy testing services to advance your research.

micetech@jax.org | 1.800.422.6423 (US) | 1.207.288.5845 (International)

Oncology

 

We specialize in the production of innovative oncology research models including PDX models and compound evaluation using PDX or cell line xenograft models, and efficacy testing of cancer immunotherapeutics.

 

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Immunology

 

Our preclinical testing facility specializes in the production of cutting-edge immunological research models including humanized CD34+and PBMC mice and compound evaluation of standardized preclinical models of autoimmune and inflammatory diseases.

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Neurobiology

 

We offer a diverse set of efficacy – testing capabilities and compound evaluation in the areas of muscular dystrophy and neurodegeneration.

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Patient-Derived Xenograft (PDX) Models


Over 300 patient-derived xenograft (PDX) tumors are available for engrafting into immunocompromised NSG™ mice for shipment to your facility or use in JAX-directed preclinical efficacy studies.

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Humanized Mice


Humanized mouse models are powerful tools for studying cancer, inflammatory and infectious disease, and hematopoiesis. We provide fast access to study-ready cohorts.

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Therapeutic Drug Evaluation Services


We evaluate the pharmacokinetics, bioavailability and efficacy of therapeutic monoclonal antibodies in vivo, using unique JAX-generated FcRn-humanized models.

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