Sergii Domanskyi, Ph.D.

Associate Computational Scientist

Development of novel computational, statistical and mathematical approaches for the analysis of Next Generation Sequencing (NGS) data.

I have a strong background in the physical and computational sciences, large-scale computational techniques, and software design, allowing me to model biological systems in multidisciplinary projects. In my post-doctoral research at Michigan State University, I have developed novel statistical and mathematical approaches in open-source packages PyIOmica, DigitalCellSorter, and DECNEO for time-series data analysis and discovery of the combinations of receptors from an extensive collection of single-cell RNA sequencing datasets. Currently, I am developing advanced computational approaches for quality control and downstream analysis of spatially resolved transcriptomics data. I am interested in algorithms exploring tumor growth, development dynamics, and gene expression regulation. I enjoy researching complex processes in the tumor microenvironment to help understand cancer biology questions through the analysis of Next Generation Sequencing data. I help automate and standardize data analysis workflows by creating Nextflow-based computational pipelines using state-of-the-art computational biology methods. My objective is to continue biostatistics analysis, develop bioinformatics algorithms and encapsulate these novel methods in reliable software for personal and HPC systems..

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Sergii Domanskyi on ORCID

Education and experience

Education

Clarkson University, Potsdam, NY
Ph.D., Physics
Adv: Prof. Vladimir Privman
2012-2018

National Technical University of Ukraine, Kyiv, Ukraine
Master of Science, Physics
Adv: Prof. Vyacheslav Gorshkov
2010-2012

National Technical University of Ukraine, Kyiv, Ukraine
Bachelor of Science, Physics
2006-2010

Experience:

Assistant Computational Scientist
The Jackson Laboratory, Bar Harbor, ME
2021-present

Post-Doctoral Research Associate
Michigan State University, East Lansing, MI
2018-2021

Visiting Graduate Student Researcher
Los Alamos National Laboratory, Los Alamos, NM
2015, 2016

Research and Teaching Assistant
Clarkson University, Potsdam, NY
2012-2018

Software Designer
Consulting and Information Technology, LLC, Kyiv, Ukraine
2011-2012