Currently manages the wet lab portion of a multi-PI proof-of-concept genetic and genomic study of predictive biology.
As an Associate Research Scientist & Program Manager for The Cube Initiative at the Jackson Laboratory, I oversee the wetlab portion of large-scale mouse projects. I am interested in the mechanisms of metabolic and cardiovascular diseases and how to use the mouse to model these diseases. The Cube Initiative is an ambitious project in a proof of concept phase currently studying Type 2 Diabetes. Here we are performing ATAC seq, RNA seq, Isoform seq, single cell RNA seq, single nucleus ATAC seq, metabolomics, proteomics, as well as in-depth metabolic phenotyping in mouse models predicted to display varied phenotypic manifestations of T2D.
I also have deep knowledge of CRISPR/Cas9 gene manipulations and mouse model generation. With my experience in Genetic Engineering Technologies, I worked with collaborators to design new mouse models. I have carried this knowledge into my personal research where I am creating new models for T2D as well as cardiovascular diseases. The new models will be used to test genetic drivers of disease predicted from multiple human data sets.
Weinstein Cardiovascular Conference Travel Award (2014)
Graduate Research Excellence Award (2013)
Graduate Travel Fellowship Recipient (2013)
First Place Graduate Research Forum (2012)
Graduate Provost Fellowship Recipient (2010-2011)
Graduate Travel Fellowship Recipient (2012)