Ron Korstanje at JAX is searching for genetic clues to slowing the progress of end-stage renal disease in patients with Alport syndrome and other kidney diseases.
Researchers in Australia and North America have recently identified a novel parvovirus in laboratory mice: the Mouse Kidney Parvovirus (MKPV; Roediger B et al., 2018). Though it has only recently been identified, this virus is suspected to be responsible for a chronic progressive kidney disease in immunodeficient mice that has been described for over 40 years.
Learn how Diversity Outbred mice allow Assistant Professor Ron Korstanje, Ph.D., to zero in on the genetic factors of chronic kidney disease—a disease that costs Americans $42 billion a year.