The Jackson Laboratory

Center for Biometric Analysis

What We Do

At the Center for Biometric Analysis (CBA), we empower JAX scientists with cutting-edge in vivo mouse phenotyping services. Our expertise spans a wide range of biological domains and disease states. Beyond data acquisition, we offer comprehensive support through experimental design consultation, staff training, and rigorous data quality control, statistical analysis, and interpretation.

Services and Technologies Offered

The CBA offers comprehensive in vivo mouse phenotyping services through four specialized cores:

  • Neurobehavioral Phenotyping (NBP core)
  • Physiology and Cardiac Phenotyping (PCP core)
  • Metabolic Phenotyping (MEP core)
  • Pre-clinical Imaging (PCI core)

Each core provides a range of services tailored to specific research needs. As our equipment and technologies evolve, the services we offer may also change to ensure we continue to meet the highest standards of scientific research.

Assays by Service Core

MEP Body Composition Analysis-EchoMRINBP Von Frey
MEP Glucose Tolerance Test with Insulin-OralPCI 2D Digital X-ray Skeletal Imaging
MEP Glucose Tolerance Test-IntraperitonealPCI Dual-Emission X-ray Absorptiometry
MEP Glucose Tolerance Test-OralPCI MRI Susceptibility Weighted Imaging
MEP Hyperglycemic Clamps (Glucose Clamps)PCI MRI-Anatomical
MEP Indirect CalorimetryPCI MRI-Angiography
MEP Insulin Tolerance TestPCI MRI-Diffusion Tensor Imaging
MEP Mixed Meal Tolerance TestPCI MRI-Diffusion Weighted Imaging, Isotropic
MEP Mixed Meal Tolerance Test with C-peptidePCI MRI-Neurite Orientation Dispersion and Density Imaging
MEP Subcutaneous Temperature MonitoringPCI MRI-Neuroanatomical
MEP Treadmill ActivityPCI MRI-Neuroanatomical, Isotropic
NBP Adhesive Tape RemovalPCI MRI-Resting State Functional (rsfMRI)
NBP Circadian Activity Monitoring (Wheels)PCI MRI-T2star Mapping, Isotropic
NBP Delayed Spatial Alternation (Y-Maze)PCI MRI-rsfMRI, Isotropic (imaging acquisition only)
NBP Elevated Zero MazePCI Ultrasonography
NBP Fear Conditioning, Contextual and CuedPCI uCT-ex vivo Imaging (Trabecular and Cortical Bone Quantification)
NBP Frailty ScreenPCI uCT-in vivo Imaging
NBP Gait Analysis (Treadscan)PCP Auditory Brainstem Response
NBP Grip StrengthPCP Blood Pressure, Non-Invasive
NBP Grooming, Induced and SpontaneousPCP DSI Telemetry Cardiovascular Blood Pressure
NBP Home Cage Monitoring (Phenotypers)PCP DSI Telemetry EEG/EMG-Deep Brain EEG
NBP Home Cage Wheel Running (Wheels)PCP DSI Telemetry EEG/EMG-Seizures
NBP Hot PlatePCP DSI Telemetry EEG/EMG-Sleep
NBP Light/Dark BoxPCP Direct & Indirect Ophthalmic Exam and Ocular Imaging
NBP Nest BuildingPCP Distortion Product Otoacoustic Emission
NBP Novel Object RecognitionPCP Echocardiography
NBP Object Place RecognitionPCP Electrocardiogram, Anesthetized
NBP Open FieldPCP Electroretinography
NBP Passive Avoidance (Shuttle Box)PCP Fundus Imaging/Florescence Angiography
NBP Pre-pulse Inhibition/Startle ReflexPCP Gross Morphology Photography
NBP RotarodPCP Intraocular Pressure Measurement, Non-Invasive
NBP Social Approach (3-Chamber)PCP Optical Coherence Tomography
NBP Spontaneous Alternation-Visual Cues (Y-Maze)PCP Piezoelectric Sleep Monitoring
NBP Stress Induced HypethermiaPCP Slit Lamp Ophthalmoscopy
NBP Tail SuspensionPCP Visual Acuity
NBP Two-Way Active Avoidance (Shuttle Box)PCP Visual Evoked Potential

 

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