Expert in the clinical characterization of genetically altered mice. Extensive experience establishing, troubleshooting, scaling up, and running at large scale and high throughput, a wide range of in vivo and ex vivo phenotypic platforms in the successful delivery of complex, multidisciplinary projects.
My early research interests in hereditary neurodegenerative disease led me to develop a specialty in the generation and characterization of genetically-engineered mouse models. Over the last 15 years I have applied my expertise to a variety of core phenotyping operations, with a results-oriented philosophy which has driven forward and supported the dissemination of research data.
Darwin College, University of Cambridge, Cambridge, England
Analysis of human NRAMP, IL8R and VIL1 genes (2q35) using yeast artificial chromosomes
1991 - 1994
University of Strathclyde, Glasgow, Scotland
Biochemistry & Immunology, Class I
1987 - 1991
1995-1998 Lieberman Fellow of Neurology, Harvard University, Massachusetts General Hospital, Molecular Neurogenetics Unit
1998 Project Leader in Transgenesis, Translocus Therapeutics, Babraham Institute, Cambridge, UK
1998-2004 Beit Memorial Research Fellow and Senior Research Associate, Cambridge Institute for Medical Research, Cambridge, UK
2004-2005 Senior Research Associate, Mouse Cancer Genetics, Wellcome Sanger Institute, Cambridge, UK
2006-2008 Senior Scientific Manager, Mouse Genetics Project, Wellcome Sanger Institute, Cambridge, UK
2008-2016 Principal Scientific Manager, Mouse Genetics Project, Wellcome Sanger Institute, Cambridge, UK
2016- Director, Center for Biometric Analysis, The Jackson Laboratory, Bar Harbor, Maine, USA