A vibrant and engaged membership drives the success of the JAXCC. The Office of JAXCC Administration connects the center’s members to resources within JAX in order to enhance and expand their research and collaborations.
If you have questions, please contact the Office of JAXCC Administration at jaxccadmin@jax.org.
Upcoming Events
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July 17 – 28, 2023
Human and Mammalian Genetics and Genomics: The 64th McKusick Short Course
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August 14 – 22, 2023
32nd Annual Short Course on Experimental Models of Human Cancer
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August 29 – 31, 2023
Workshop on Stereotaxic Surgery in the Laboratory Mouse
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September 11 – 13, 2023
Workshop on Vascular Catheterization in the Laboratory Mouse
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March 19 – 21, 2024
Workshop on Stereotaxic Surgery in the Laboratory Mouse
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May 17 – 23, 2024
Workshop on Techniques in Modeling Human Cancer in Mice
Recent Tweets
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RT @jacksonlab: With T cells as troops in our immune system army, and MAIT cells acting as a special forces unit, Professor Derya Unutmaz w… -
RT @jacksonlab: 📚 The @JAX_Education #CancerShortCourse includes seminars from leaders in cancer genetics, cancer #cellbiology, emerging an…
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RT @jacksonlab: #Postdoc job of the week: Join the Shultz Lab to develop humanized mouse models and apply these models to the study of hema…
News
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5/23 Two JAX researchers win Outstanding Paper Prize
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5/4 Advancing cancer research with the latest therapies
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3/14 How does inflammation and aging tie to the AP-1 Complex?
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2/23 Investigating the roles of mesenchymal cells in lung metastasis of breast cancer
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2/22 Examining hematopoietic stem cells decline with age
Genetics. 2023 May 4; 224(1)
The Gene Ontology knowledgebase in 2023
Gene Ontology Consortium, Aleksander SA, Balhoff J, Carbon S, Cherry JM, Drabkin HJ, et al.
View publicationGenetics. 2023 May 4; 224(1)
2022 updates to the Rat Genome Database: a Findable, Accessible, Interoperable, and Reusable (FAIR) resource
Vedi M, Smith JR, Thomas Hayman G, Tutaj M, Brodie KC, De Pons JL, et al.
The Rat Genome Database (RGD, https://rgd.mcw.edu) has evolved from simply a resource for rat genetic markers, maps, and genes, by adding multiple genomic data types and extensive disease and phenotype annotations and developing tools to effectively mine, analyze, and visualize the available data, to empower investigators in their…
© The Author(s) 2023. Published by Oxford University Press on behalf of the Genetics Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.J Steroid Biochem Mol Biol. 2023 Apr 11; 231:106308
The impact of vitamin D on cancer: A mini review
Seraphin G, Rieger S, Hewison M, Capobianco E, Lisse TS
In this review, we summarize the most recent advances in vitamin D cancer research to provide molecular clarity, as well as its translational trajectory across the cancer landscape. Vitamin D is well known for its role in regulating mineral homeostasis; however, vitamin D deficiency has also been linked to the development and progression of a number of cancer types. Recent epigenomic, transcriptomic, and proteomic studies have revealed novel vitamin D-mediated biological mechanisms that regulate cancer cell…
Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.Cancer Cell. 2023 Apr 10; 41(4):641-645
Challenges and opportunities for modeling aging and cancer
Anczuków O, Airhart S, Chuang JH, Coussens LM, Kuchel GA, Korstanje R, et al.
Age is among the main risk factors for cancer, and any cancer study in adults is faced with an aging tissue and organism. Yet, pre-clinical studies are carried out using young mice and are not able to address the impact of aging and associated comorbidities on disease biology and treatment outcomes. Here, we discuss the limitations of current mouse cancer models and suggest…
Copyright © 2023 Elsevier Inc. All rights reserved.Cancer Epidemiol Biomarkers Prev. 2023 Apr 3; 32(4):487-495
Priorities to Promote Participant Engagement in the Participant Engagement and Cancer Genome Sequencing (PE-CGS) Network
Schuster AL, Crossnohere NL, Bachini M, Blair CK, Carpten JD, Claus EB, et al.
Engaging diverse populations in cancer genomics research is of critical importance and is a fundamental goal of the NCI Participant Engagement and …
©2023 The Authors; Published by the American Association for Cancer Research.Nat Rev Genet. 2022 Dec; 23(12):760-771
Extrachromosomal DNA amplifications in cancer
Yi E, Chamorro González R, Henssen AG, Verhaak RGW
Extrachromosomal DNA (ecDNA) amplification is an important driver alteration in cancer. It has been observed in most cancer types and is associated with worse patient outcome. The functional impact of ecDNA has been linked to its unique properties, such as its circular structure that is associated with altered chromatinization and epigenetic regulatory landscape, as well as its ability to randomly segregate during cell division, which fuels intercellular copy number heterogeneity. Recent investigations suggest that ecDNA is…
© 2022. Springer Nature Limited.