The study of structural genomic variation in human biology, evolution and disease
The research laboratory of Dr. Charles Lee at The Jackson Laboratory for Genomic Medicine develops and applies state-of-the-art technologies to study structural genomic variation and its contribution to human diseases, and vertebrate genome evolution.
2014 - Thompson Reuters Citation Laureate in Physiology and Medicine
2012 - Fellow, AAAS American Association for the Advancement of Science
2012 - Chen Global Investigator Award, Human Genome Organization (HUGO)
2012 - Vandenberghe Chair Award, Katholic University of Leuven, Belgium
2010 - George W. Brumley, Jr., MD Memorial Award, Duke University, Durham, North Carolina, USA
2008 - C. Thomas Caskey Lectureship, University of South Carolina, Columbia, South Carolina, USA
2007 - American Association for Cancer Research Inaugural Team Award, American Association for Cancer Research
2002 - Stanley L. Robbins Research Award, Department of Pathology, Brigham and Women’s Hospital
1996-1998 - NSERC Postdoctoral Fellowship, Natural Sciences and Engineering Research Council of Canada
1996 - MRC Postdoctoral Fellowship, Medical Research Council of Canada
1994-1996 - AHFMR PhD Studentship, Alberta Heritage Foundation for Medical Research
1994 - 75th Anniversary Faculty of Medicine Scholarship, University of Alberta
Perry GH, Dominy NJ, Claw KG, Lee AS, Fiegler H, Redon R, Werner J, Villanea FA, Mountain JL, Misra R, Carter NP, Lee C*, Stone AC. Diet and the evolution of human amylase gene copy number variation. Nat Genet 39(10):1256-60, 2007. *co-senior author
Iafrate AJ, Feuk L, Rivera MN, Listewnik ML, Donahoe PK, Qi Y, Scherer SW, Lee C. Detection of large-scale variation in the human genome. Nat Genet 36(9):949-51, 2004.
Yang L, Luquette LJ, Gehlenborg N, Xi R, Haseley PS, Hsieh CH, Zhang C, Ren X, Protopopov A, Chin L, Kucherlapati R, Lee C*, Park PJ. Diverse mechanisms of somatic structural variations in human cancer genomes. Cell 153(4): 919-29, 2013. *Co-senior author
Brown KH, Dobrinski KP, Lee AS, Gokcumen O, Mills RE, Shi X, Chong WW, Chen JY, Yoo P, David S, Peterson SM, Raj T, Choy KW, Stranger BE, Williamson RE, Zon LI, Freeman JL, Lee C. Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis. Proc Natl Acad Sci U S A 109(2):529-34, 2012
HUGO President Charles Lee contemplates HUGO’s place in the global research and clinical communities and its value moving...
To celebrate the 60th Anniversary of the Human and Mammalian Genetics and Genomics: The McKusick Short Course, The Jackson...
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